Tuberc Respir Dis.  2011 Feb;70(2):160-164. 10.4046/trd.2011.70.2.160.

A Case of Cranial Nerve Palsy as a Paraneoplastic Syndrome in Non-Small Cell Lung Cancer

Affiliations
  • 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. khj57@yuhs.ac
  • 2Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
  • 3Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.

Abstract

Paraneoplastic neurologic syndrome is a group of assorted disorders resulting from damage to the nervous system in cancer, remote from primary site, and not related to metastasis, infection, or metabolic disorder associated with cancer. Patient with small cell lung cancer sometimes shows various neurological syndromes, but patient with non-small cell lung cancer rarely shows neurologic syndromes and few antineuronal antibodies have been found. Here, we report a case of 53-year-old male patient who developed ptosis and extraocular muscular limitation of left eye due to third and forth cranial nerve palsy in non-small cell lung cancer without brain metastasis. These neurologic symptoms improved after lobectomy without any other treatment immunotherapy.

Keyword

Paraneoplastic Syndromes, Nervous System; Carcinoma, Non-Small-Cell Lung; Paralysis, Cranial Nerves

MeSH Terms

Antibodies
Brain
Carcinoma, Non-Small-Cell Lung
Cranial Nerve Diseases
Cranial Nerves
Eye
Humans
Immunotherapy
Male
Middle Aged
Neoplasm Metastasis
Nervous System
Neurologic Manifestations
Paraneoplastic Syndromes
Paraneoplastic Syndromes, Nervous System
Small Cell Lung Carcinoma
Antibodies
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