Korean J Gastrointest Endosc.  2011 Jun;42(6):428-432.

Two Cases of Xanthogranulomatous Cholecystitis and Gallbladder Cancer with Hemobilia

  • 1Department of Internal Medicine, Daegu Fatima Hospital, Daegu, Korea. cognex@dreamwiz.com
  • 2Department of Surgery, Daegu Fatima Hospital, Daegu, Korea.
  • 3Department of Pathology, Daegu Fatima Hospital, Daegu, Korea.


Hemobilia is a rare upper gastrointestinal (GI) bleeding phenomenon usually caused by trauma but may occur due to various liver and pancreatobiliary diseases. Causes related to gallbladder disease include vascular disorders, malignancy, polyps, heterotopic GI mucosa, acalculous inflammation, and most commonly gallstones. Most cases are treated with a cholecystectomy. If hemobilia is detected, efforts must be made to exclude malignancy because hemobilia develops from both benign and malignant disease. Particularly in gallbladder disease with hemobilia, the possibility of gallbladder carcinoma should be considered. We report two cases of hemoblia by endoscopic retrograde cholangiopancreatography and duodenoscopy, with a review of the literature. The first case was xanthoglanulomatous cholesystitis and the second case was gallbladder cancer disclosed by cholecystectomy.


Hemobilia; Cholecystitis; Gallbladder neoplasm
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