Korean J Gastrointest Endosc.  2011 Jul;43(1):25-29.

A Case of Gastric Low-grade MALT Lymphoma Induced by a Helicobacter heilmannii-like Organism

• Oh DH
• Kim NH
• Cho YJ
• Song TJ
• Bae WK
• Kim KA
• Lee JS
• Joo M

Abstract

Helicobacter heilmannii is a Gram negative, long spiral-shaped organism associated with zoonotic infections acquired from primates including cats and dogs. Infection with H. heilmannii leads to gastritis, peptic ulcer disease, gastric adenocarcinoma, and gastric mucosa-associated lymphoid tissue (MALT) lymphoma. We experienced a 54-year-old man with dyspepsia who was diagnosed with primary gastric MALT lymphoma (stage IE1) associated with a H. heilmannii-like organism. Upper gastrointestinal endoscopy revealed only microvascular dilatation and mucosal granularity without elevated or ulcerative lesions at the stomach angle. He was probably infected by a pet dog. The man was treated with eradication therapy for 2 weeks including lansoprazole, amoxicillin, and clarithromycin. Four weeks after eradication of the H. heilmannii-like organism, follow-up endoscopy and pathological biopsy findings showed complete remission of the gastric MALT lymphoma.

Keyword

Helicobacter heilmannii; Helicobacter pylori; Gastric MALT lymphoma

MeSH Terms

2-Pyridinylmethylsulfinylbenzimidazoles
Adenocarcinoma
Amoxicillin
Animals
Biopsy
Cats
Clarithromycin
Dilatation
Dogs
Dyspepsia
Endoscopy
Endoscopy, Gastrointestinal
Follow-Up Studies
Gastritis
Helicobacter
Helicobacter heilmannii
Helicobacter pylori
Humans
Lymphoid Tissue
Lymphoma
Lymphoma, B-Cell, Marginal Zone
Middle Aged
Peptic Ulcer
Primates
Stomach
Stomach Diseases
Ulcer
2-Pyridinylmethylsulfinylbenzimidazoles
Amoxicillin
Clarithromycin