J Korean Med Sci.  1992 Jun;7(2):184-188. 10.3346/jkms.1992.7.2.184.

Pancreatoblastoma: histopathological and ultrastructural analysis of two cases

Affiliations
  • 1Department of Pathology Seoul National University College of Medicine, Korea.

Abstract

Pancreatoblastoma has been described in children and characterized by unique histologic features and excellent clinical course. Ultrastructural and immunohistochemical studies of pancreatoblastoma reveal either exocrine alone or both endocrine and exocrine differentiation. We present two cases of pancreatoblastoma in children in which immunohistochemical and ultrastructural examination failed to demonstrate features of either enzyme or hormone production and which became worse in clinical course. We assume that pancreatoblastomas are tumors which differentiate more toward acinar or ductal elements than toward islet cell.

Keyword

Pancreatoblastoma; Exocrine differentiation; Pancreas; Childhood

MeSH Terms

Carcinoma/*pathology/ultrastructure
Child, Preschool
Female
Humans
Pancreatic Neoplasms/*pathology/ultrastructure
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