J Vet Sci.  2012 Sep;13(3):327-330. 10.4142/jvs.2012.13.3.327.

Use of canine small intestinal submucosa allograft for treating perineal hernias in two dogs

Affiliations
  • 1Department of Veterinary Surgery, College of Veterinary Medicine, Konkuk University, Seoul 143-701, Korea. hykim@konkuk.ac.kr
  • 2Department of Veterinary Clinical Pathology, College of Veterinary Medicine, Konkuk University, Seoul 143-701, Korea.
  • 3Department of Veterinary Radiology, College of Veterinary Medicine, Konkuk University, Seoul 143-701, Korea.

Abstract

Here, we describe two dogs in which canine small intestinal submucosa (SIS) was implanted as a biomaterial scaffold during perineal herniorrhaphy. Both dogs had developed severe muscle weakness, unilaterally herniated rectal protrusions, and heart problems with potential anesthetic risks. Areas affected by the perineal hernia (PH) located between the internal obturator and external anal sphincter muscles were reconstructed with naive canine SIS sheets. In 12 months, post-operative complications such as wound infections, sciatic paralysis, rectal prolapse, or recurrence of the hernia were not observed. Symptoms of defecatory tenesmus also improved. Neither case showed any signs of rejection or specific immune responses as determined by complete and differential cell counts. Our findings demonstrate that canine SIS can be used as a biomaterial scaffold for PH repair in dogs.

Keyword

biomaterial scaffold; canine small intestinal submucosa (canine SIS); perineal hernia

MeSH Terms

Animals
Biocompatible Materials
Dog Diseases/*surgery
Dogs
Hernia, Abdominal/surgery/*veterinary
Herniorrhaphy/veterinary
Intestinal Mucosa/*transplantation
Intestine, Small/*transplantation
Male
Perineum/surgery
Postoperative Complications/veterinary
Transplantation, Homologous/veterinary

Figure

  • Fig. 1 In Case 1, Positive contrast radiograph and magnetic resonance imaging scans. (A) Lateral view showed that the rectum protruded into the hernia sac by barium enema. (B) The levator ani, coccygeal, and obturator muscles appeared around the dilated rectum, and the canine prostate was found to be hyperplastic on the T1-weighted image.

  • Fig. 2 Intraoperative photographs of perineal herniorrhaphy using canine small intestinal submucosa (SIS) in Case 1. (A) The four-layered canine SIS sheet was prepared. After placing the deviated rectum in its original location, the levator ani, coccygeus, and internal obturator muscles were identified. (B) The canine SIS sheet was placed between the perineal muscles.

  • Fig. 3 (A) In Case 2, calculi were identified near the os penis by radiography, and a PH was observed with displacement by the feces-filled rectum. (B) The canine SIS sheet was placed between the perineal muscle structures during perineal herniorrhaphy.


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