J Korean Acad Nurs.  2012 Apr;42(2):190-198. 10.4040/jkan.2012.42.2.190.

Effects of a Smoking Cessation Education on Smoking Cessation, Endothelial Function, and Serum Carboxyhemoglobin in Male Patients with Variant Angina

• Cho SH

• KMID: 1376060
• DOI: http://doi.org/10.4040/jkan.2012.42.2.190

Abstract

PURPOSE
The aim of this study was to evaluate the effects of a smoking cessation education on endothelial function and carboxyhemoglobin levels in smokers with variant angina.
METHODS
A nonequivalent control group pretest-posttest design was used. Participants were 60 male smokers with variant angina admitted to one hospital: the control group (30) between September and December, 2009, and the experimental group (30) between February and May, 2010. Endothelial function, as defined by flow-mediated vasodilation (FMD) of the brachial artery, and serum carboxyhemoglobin (COHb) were determined at baseline and at 3 months after the initiation of education in both groups.
RESULTS
Three months after the program, smoking cessation was successful in 22 of the 30 smokers in the experimental group, but only in 4 of 30 smokers in the control group (p<.001). After the education, the experimental group showed a significant increase in FMD, and a significant decreased in serum COHb compared with the control group.
CONCLUSION
The findings indicate that this smoking cessation education program is effective for hospitalized smokers with variant angina.

Keyword

Angina pectoris; Smoking cessation; Endothelium

MeSH Terms

Adult
Angina Pectoris, Variant/blood/*physiopathology
Brachial Artery/physiology
Carboxyhemoglobin/*analysis
Endothelium, Vascular/*physiology
Humans
Male
Middle Aged
*Program Evaluation
Smoking/psychology
*Smoking Cessation
Vasodilation

Figure

• 

  Figure 1 Research design of this study.

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