J Korean Med Sci.  2012 May;27(5):489-494. 10.3346/jkms.2012.27.5.489.

Completeness of Cancer Case Ascertainment in Korea Radiation Effect and Epidemiology Cohort Study

  • 1Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea. yoahn@plaza.snu.ac.kr
  • 2Institute of Radiation Effect & Epidemiology, Seoul National University Medical Research Centre, Seoul, Korea.


The aim of this study was to evaluate whether the completeness of case ascertainment during the follow-up of a cohort differed between the exposed and the nonexposed groups in Korea Radiation Effect and Epidemiology Cohort (KREEC). The completeness was defined as the proportion of the number of detected cases to the number of estimated cases, in which the estimation was performed by capture-recapture method. Data were obtained from the cancer registries, death certificates, and medical records during years 2004-2007. Among 11,367 subjects in the exposed group and 24,809 subjects in the unexposed group, the completeness of cancer case ascertainment were 88.2% vs 87.2% in cancer registry, 38.2% vs 41.1% in death certificate and 57.9% vs 62.0% in medical records data, 96.9% vs 97.1% for all combined sources and were not statistically different between the two groups. In conclusion, the method of ascertaining the cases in the KREEC was not biased depending on the exposure status, and thus adds credibility to the outcomes of the KREEC study as well as confirming the incident cases in the two groups.


Cohort Studies; Data Collection; Neoplasms; Validity

MeSH Terms

Cohort Studies
Data Interpretation, Statistical
Death Certificates
Disease Notification/statistics & numerical data
Follow-Up Studies
Medical Records/statistics & numerical data
Registries/statistics & numerical data
Republic of Korea/epidemiology
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