Korean J Radiol.  2002 Dec;3(4):264-266. 10.3348/kjr.2002.3.4.264.

Retroperitoneal Malignant Mesenchymoma: A Case of Mesenchymal Mixed Tumor with Osteosarcoma, Leiomyosarcoma, Liposarcoma and Fibrosarcoma

• Choi JE
• Chung HJ
• Yoo WJ
• Chung MH
• Sung MS
• Lee HG
• Park IY
• Kim J

• KMID: 1118795
• DOI: http://doi.org/10.3348/kjr.2002.3.4.264

Abstract

Malignant mesenchymoma is an interesting but very rare tumor in which malignant differentiation has occurred twice or more. We report a case of retroperitoneal malignant mesenchymoma consisting of osteosarcoma, leiomyosarcoma, liposarcoma and fibrosarcoma. Abdominal CT showed a large retroperitoneal mass with two separate and distinct parts, namely an area of prominent calcification and one of clearly enhancing solid components. The mass contained histologically distinct tumorous components with no histologic admixure at the interfaces. The densely calcified nodule corresponded to osteosarcoma, and the noncalcified clearly enhancing nodules to leiomyosarcoma, liposarcoma and fibrosarcoma.

Keyword

Malignant mesenchymoma; Retroperitoneum, CT; Sarcoma

MeSH Terms

Case Report
Fibrosarcoma/*radiography
Human
Leiomyosarcoma/*radiography
Liposarcoma/*radiography
Male
Mesenchymoma/*radiography
Middle Age
Osteosarcoma/*radiography
Retroperitoneal Neoplasms/*radiography
Tomography, X-Ray Computed

Figure

• 

  Fig. 1 A 47-year-old man with retroperitoneal malignant mesenchymoma. A. Plain abdominal radiograph demonstrates a large mass with multiple, dense, large, stippled calcifications in the left-side abdomen. B. Contrast-enhanced abdominal CT scan at the renal level depicts a large conglomerate mass with densely calcified nodules, shown at histopathologic correlation to be consistent with osteosarcoma, in the left-side reteroperitoneum. The mass invades the left kidney (arrows). C. Contrast-enhanced abdominal CT scan, caudal to that seen in (B), depicts lobulated non-calcified soft tissue nodules (arrows) with strong peripheral enhancement and, in some areas, central low attenuation. The nodules correspond to leiomyosarcoma, liposarcoma, and fibrosarcoma. D. Microscopically, the osteosarcomatous component consists of a central malignant osteoid within a background of malignant spindle cells (original magnification, ×100; hematoxylin-eosin staining). E. Microscopically, the leiomyosarcomatous component contains typical blunt-ended nuclei with mitotic configuration (original magnification, ×100; hematoxylin-eosin staining). F. Microscopically, the liposarcomatous component contains occasional scattered lipoblasts between fat cells (original magnification, ×100; hematoxylin-eosin staining).

Reference

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