Korean J Hepatol.  2010 Dec;16(4):401-404. 10.3350/kjhep.2010.16.4.401.

Hepatogastric fistula caused by direct invasion of hepatocellular carcinoma after transarterial chemoembolization and radiotherapy

Affiliations
  • 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. dyk1025@yuhs.ac
  • 2Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea.
  • 3Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
  • 4Liver Cancer Special Clinic, Yonsei University College of Medicine, Seoul, Korea.
  • 5Liver Cirrhosis Clinical Research Center, Seoul, Korea.

Abstract

A 63-year-old man with a history of hepatitis-B-related hepatocellular carcinoma (HCC) in the left lateral portion of the liver received repeated transcatheter arterial chemoembolization (TACE) and salvage radiotherapy. Two months after completing radiotherapy, he presented with dysphagia, epigastric pain, and a protruding abdominal mass. Computed tomography showed that the bulging mass was directly invading the adjacent stomach. Endoscopy revealed a fistula from the HCC invading the stomach. Although the size of the mass had decreased with the drainage through the fistula, and his symptoms had gradually improved, he died of cancer-related bleeding and hepatic failure. This represents a case in which an HCC invaded the stomach and caused a hepatogastric fistula after repeated TACE and salvage radiotherapy.

Keyword

Hepatocellular carcinoma; Invasion; Hepatogastric fistula; Stomach

MeSH Terms

Carcinoma, Hepatocellular/complications/radiography/*therapy
*Chemoembolization, Therapeutic
Drainage
Gastric Fistula/*etiology
Gastroscopy
Hepatitis B/diagnosis
Humans
Liver Diseases/*etiology
Liver Neoplasms/complications/radiography/*therapy
Male
Middle Aged
Neoplasm Invasiveness
Stomach/pathology
Tomography, X-Ray Computed
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