J Vet Sci.
2005 Jun;6(2):87-96.
Human embryonic stem cells and therapeutic cloning
- Affiliations
-
- 1Department of Theriogenology and Biotechnology, College of Veterinary Medicine, Seoul National University, Seoul 151-742, Korea. hwangws@snu.ac.kr
- 2The Xenotransplantation Research Center, Seoul National University Hospital, Seoul 110-744, Korea.
- 3School of Agricultural Biotechnology, Seoul National University, Seoul 151-742, Korea. hwangws@snu.ac.kr
Abstract
- The remarkable potential of embryonic stem (ES) cells is their ability to develop into many different cell types. ES cells make it possible to treat patients by transplanting specialized healthy cells derived from them to repair damaged and diseased cells or tissues, known as "stem cell therapy". However, the issue of immunocompatibility is one of considerable significance in ES cell transplantation. One approach to overcome transplant rejection of human ES (hES) cells is to derive hES cells from nuclear transfer of the patient's own cells. This concept is known as "therapeutic cloning". In this review, we describe the derivations of ES cells and cloned ES cells by somatic cell nuclear transfer, and their potential applications in transplantation medicine.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Ethical Issues on Embryonic Stem Cell Research
- Current Concepts of Stem Cell Therapy
- Current status and concepts of stem cell therapy
- Problems Associated with Establishment of Human Embryonic Stem Cell
- The Use of Canine Bone-Marrow Stromal Cell Line, DO64, as Feeder Cells for The Efficient Cloning of Human B Lymphoblastoid Cell Lines ( B-LCLs )
