J Vet Sci.  2007 Mar;8(1):99-101. 10.4142/jvs.2007.8.1.99.

Primary chondrosarcoma in the skull of a dog

• Kim H
• Nakaichi M
• Itamoto K
• Taura Y

• KMID: 1104243
• DOI: http://doi.org/10.4142/jvs.2007.8.1.99

Abstract

Chondrosarcoma of the skull is a rare primary malignant tumor that is slow-growing, but locally aggressive. A 5-year-old, golden retriever was presented to our hospital with a swelling in the left side of her head, and the swelling had slowly enlarged over the previous month. There were no significant changes on the neurological examination. A computed tomography scan revealed a large mass involving bone destruction and prominent matrix mineralization. T1-weighted magnetic resonance imaging showed a slightly low-signal intensity area and a T2-weighted image revealed marked, high-signal intensity. There was compression of the adjacent brain parenchyma. Histopathological examination confirmed the lesion to be a chondrosarcoma.

Keyword

chondrosarcoma; computed tomography; dog; magnetic resonance imaging; skull

MeSH Terms

Animals
Chondrosarcoma/pathology/*veterinary
Dog Diseases/*pathology
Dogs
Magnetic Resonance Imaging/veterinary
Skull/*radiography
Tomography, X-Ray Computed/veterinary

Figure

• 

  Fig. 1 Radiograph of the head revealed lytic lesion with endosteal scalloping (A, arrow) and calcification within the soft tissue (B, arrow).

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  Fig. 2 CT scan showed bone destruction of the skull (A) and matrix calcification (A, B).

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  Fig. 3 Transverse T1-weighted MRI (A) and its contrastenhanced image (C) showed a slightly low-signal intensity area and mild marginal enhancement around the mass, respectively. T2-weighted image revealed the marked high-signal intensity (B, D) and some compression of the adjacent brain parenchyma (D).

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  Fig. 4 Histopathological finding revealed proliferation of the atypical chondrocytes (arrows) and cartilaginous component (C). H&E stain, ×400.

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