J Vet Sci.  2006 Mar;7(1):89-90. 10.4142/jvs.2006.7.1.89.

Malignant ocular melanoma in a dog

Affiliations
  • 1College of Veterinary Medicine, Seoul National University, Seoul 151-742, Korea. kmseo@snu.ac.kr

Abstract

A mongrel male dog of three years old was referred to the Seoul National University Veterinary Teaching Hospital following a one month history of glaucoma. On ophthalmic examination, hyphema, glaucoma, uveitis, iridal mass, and loss of vision were noted in the right eye. Ultrasonography and computed tomography revealed a mass with involvement of the entire uvea. Radiographic evaluation did not reveal any evidence of distant metastasis. The right eye was surgically removed because of the high likelihood of neoplasia. A histologic diagnosis of malignant uveal melanoma was made.

Keyword

melanoma; uvea; dog

MeSH Terms

Animals
Dog Diseases/*pathology/surgery
Dogs
Eye Enucleation/veterinary
Histocytochemistry/veterinary
Male
Melanoma/pathology/surgery/*veterinary
Uveal Neoplasms/pathology/surgery/*veterinary

Figure

  • Fig. 1 Clinical photography of the right eye. The episcleral and conjunctival vessels were severely congested and there was a raised mass in the episcleral region (a); Pigmented mass from the iris to the choroid and partially non-pigmented region in dorsal part of the iris mass (arrow) were shown in the cut surface of the globe (b); Sonographic image of dorsal scanning showed the anterior uveal mass (arrowhead) and the choroidal mass (arrow) (c); Reformatted CT image through the eyeballs showed uveal mass extended from the iris to the choroid in the right eye (arrow) and revealed no evidence of extraocular tumor extension (d).

  • Fig. 2 Neoplastic cells of the intraocular mass (A) are infiltrated into adjacent anterior uveal tract (B) and sclera (C). H&E stain, ×12.5.

  • Fig. 3 There are bundles of the lightly pigmented spindle shaped cells with variably distinct cell borders in the intraocular mass. H&E stain, ×200.


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