Yonsei Med J.  1964 Dec;5(1):1-5. 10.3349/ymj.1964.5.1.1.

Some Variations between Normal and Leukemic Leukocytes

Affiliations
  • 1Faculty of Medicine, University of Ottawa, Ottawa, Canada.

Abstract


Methods
, data, and discussions of experiments concerning agglutination of human leukemic leukocytes with guinea pig serum and the alkaline phosphatase staining technique by the Azo-dye method are given. An important fact evident from studies of alkaline phosphatase is that there can be chemical differences between cells whose morphology is identical. Even though the results obtained here in the small group of leukemic cases studied by the guinea pig serum agglutination method are not very reproducible, the idea that an antigen-antibody reaction for the determination of leukemia exists, very appealing.

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