Korean J Ophthalmol.  2007 Jun;21(2):85-89. 10.3341/kjo.2007.21.2.85.

Effect of Base Curve Radius of Therapeutic Lenses on Epithelial Healing after Laser-Assisted Subepithelial Keratectomy

• Seo JH
• Wee WR
• Lee JH
• Kim MK

• KMID: 1101909
• DOI: http://doi.org/10.3341/kjo.2007.21.2.85

Abstract

PURPOSE: To determine the effect of the base curve radius (BCR) of therapeutic soft contact lens (T-lens) on epithelial healing after laser-assisted subepithelial keratectomy (LASEK). METHODS: Ninety-two eyes in 47 patients with myopia were prospectively evaluated after LASEK. All the patients wore T-lenses with the BCR (R1) randomly chosen after LASEK. The T-lenses were removed after complete healing of the epithelial wounds. We calculated an estimated BCR (R2) from postoperative topography using a diopter conversion table. The patients were divided into two groups according to the differences between the BCR (R1) and the estimated BCR (R2). The flat fitting group was R1 > R2 (Group A), and the steep fitting group was R1R2) had 53 eyes, and Group B (R1

Keyword

Base curve radius (BCR); LASEK; Therapeutic contact lens

MeSH Terms

Adult
Contact Lenses, Hydrophilic/*standards
Epithelium, Corneal/*pathology
Equipment Design
Female
Follow-Up Studies
Humans
Keratectomy, Subepithelial, Laser-Assisted/*methods
Male
Postoperative Period
Prospective Studies
Refraction, Ocular
Refractive Errors/pathology/*therapy
Surface Properties
Treatment Outcome
Visual Acuity
*Wound Healing

Figure

• 

  Fig. 1 Estimated mean and standard errors for number of days wearing therapeutic contract lens in Group A and Group B. Group A showed a shorter epithelial healing time than Group B (5.8±1.7 days vs. 6.7±2.1 days, p=0.04). This implies selecting a flat fitting BCR lens is more beneficial on wound healing than a steep fitting lens after LASEK. Group A=Patients with flat fitting (R1>R2), Group B=Patients with steep fitting (R1

Reference

1. Dastjerdi MH, Soong HK. LASEK (laser-assisted subepithelial keratomileusis). Curr Opin Ophthalmol. 2002. 13:261–263.

2. Litwak S, Zadok D, Garcia-de Quevedo V, et al. Laser-assisted subepithelial keratectomy versus photorefractive comparative study. J Cataract Refract Surg. 2002. 28:1330–1333.

3. Szerenyi KD, Wang X, Gabrielian K, et al. Keratocyte loss and repopulation of anterior corneal stroma after deepithelialization. Arch Ophthalmol. 1994. 112:973–976.

4. Christie CL. Therapeutic contract lens. Contract Lens Anterior Eye. 1999. 22:Suppl 1. S20–S25.

5. Mannis MJ. Smolin G, Thoft RA, editors. Therapeutic contact lenses. The cornea. 1994. v. 1:3rd ed. Boston: Little Brown and company;chap. 26.

6. Smiddy WE, Hamburg TR, Kracher GP, et al. Therapeutic contact lenses. Ophthalomology. 1990. 97:291–295.

7. Kaufman H, Gasset AR. Therapeutic soft bandage lenses. Int Ophthalmol Clin. 1970. 10:379–385.

8. Lee JB, Seong GJ, Lee JH, et al. Comparision of laser epithelial keratomileusis and photorefractive keratectomy for low to moderate myopia. J Cataract Refract Surg. 2001. 27:565–570.

9. Nakamura K, Kurosaka D, Bissen-Miyajima H, et al. Intact corneal epithelium is essential for the prevention of stromal haze after laser assisted in situ keratomileusis. Br J Ophthalmol. 2001. 85:209–213.

10. Li Q, Ashraf MF, Bekoe NA, et al. The role of apoptosis in the early corneal wound healing after excimer laser keratectomy in the rat. Graefes Arch Clin Exp Ophthalmol. 2000. 238:853–860.

11. Wilson SE, Li Q, Weng J, et al. The Fas/Fas ligand system and other modulations of apoptosis in the cornea. Invest Ophthalmol Vis Sci. 1996. 37:1582–1592.

12. Helena MC, Baerveldt F, Kim WJ, et al. Keratocyte apoptosis after corneal surgery. Invest Ophthalmol Vis Sci. 1998. 39:276–283.

13. Moller-Pedersen T, Cavanagh HD, petrol WM, et al. Corneal haze development after PRK is regulated by volume of stromal tissue removal. Cornea. 1998. 17:627–639.

14. Sohn JH, Choi SK, Lee JH. The effect of disposable bandage contact lenses on time and velocity of corneal epithelial healing after myopic epikeratoplasty. J Korean Ophthalmol Soc. 1995. 36:1422–1428.

15. Choi JY, Joo CK. The effect of topical prostaglandin synthesis inhibitor and therapeutic contact lens on the pain and corneal reepithelization after excimer laser PRK. J Korean Ophthalmol Soc. 1997. 38:936–941.

16. Yeom HY, Park SB, Lee HK, et al. Effects of amniotic membrane after LASEK on epithelial healing clinical and refractive outcomes. J Korean Ophthalmol Soc. 2004. 45:195–202.

17. Gemoules G. Therapeutic effects of contact lenses after refractive surgery. Eye contact Lens. 2005. 31:12–22.