Korean J Ophthalmol.  2006 Jun;20(2):109-112. 10.3341/kjo.2006.20.2.109.

Recurrent Intraocular Pressure Elevation during Hemodialysis in a Patient with Neovascular Glaucoma

Affiliations
  • 1The Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine Hospital, Seoul, Korea. sjha@yumc.yonsei.ac.kr

Abstract

PURPOSE: To report a patient with symptomatic intraocular pressure (IOP) elevation in an eye with neovascular glaucoma (NVG) during hemodialysis. METHODS: Case report. RESULTS: Recurrent episodes of severe ocular pain and elevated IOP in the NVG eye were noted during hemodialysis in a 29-year-old man. The patient was recently diagnosed at our ophthalmology clinic with NVG due to central retinal vein occlusion. IOP was temporarily controlled after the Ahmed valve implantation. However, after the fibrous membrane developed and occluded the tip of the Ahmed valve, IOP elevation during hemodialysis recurred. Further treatments with intravenous mannitol, oral carbonic anhydrase inhibitor, topical antiglaumatic agents and subconjunctival 5-fluorouracil (5-FU) injections all failed to control relapsing pain and IOP elevation. Eventually, evisceration and hydroxyappatite implantation were performed. CONCLUSIONS: Physicians must be alert to the possibility of IOP elevation in glaucomatous eyes during hemodialysis.

Keyword

Ahmed valve; Hemodialysis; Intraocular pressure (IOP); Neovascular glaucoma (NVG)

MeSH Terms

Renal Dialysis/*adverse effects
Recurrence
Male
Kidney Failure, Chronic/complications/*therapy
Intraocular Pressure/*physiology
Humans
Glaucoma, Neovascular/complications/*physiopathology/surgery
Glaucoma Drainage Implants
Follow-Up Studies
Filtering Surgery/instrumentation
Adult

Figure

  • Fig. 1 Intraocular pressure shifts according to dates and events. Intraocular pressures were checked by Goldmann applanation tonometry (mmHg). *ACP=anterior chamber paracentesis; †HD =hemodialysis; ‡5-FU=subconjuctival 5-fluorouracil injection; §man 400=intravenous mannitolization 400 cc; OD=right eye; OS =left eye. Intraocular pressure of the NVG eye (right eye) of the patient showed a marked increase after hemodialysis (p=0.028). The intraocular pressure of the left eye remained within the normal range without statistical change regarding hemodialysis (p=0.066).


Reference

1. Ramsell JT, Ellis PP, Paterson CA. Intraocular pressure changes during hemodialysis. Am J Ophthalmol. 1971. 72:926–930.
2. Burn RA. Intraocular pressure during haemodialysis. Br J Ophthalmol. 1973. 57:511–513.
3. Gafter U, Pinkas M, Hirsch J, et al. Intraocular pressure in uremic patients on chronic hemodialysis. Nephron. 1985. 40:74–75.
4. Leiba H, Oliver M, Shimshoni M, Bar-Khayim Y. Intraocular pressure fluctuations during regular hemodialysis and ultrafiltration. Acta Ophthalmol. 1990. 68:320–322.
5. Jung SK, Lee SK, Kim JH. Intraocular pressure change by the hemodialysis. J Korean Ophthalmol Soc. 1995. 36:2195–2201.
6. Choong YF, Menage MJ. Symptomatic acute raised IOP following hemodialysis in a patient with end stage renal failure. Br J Ophthalmol. 1998. 82:1342–1350.
7. Masuda H, Shibuya Y, Ohira A. Markedly increased unilateral intraocular pressure during hemodialysis in a patient with ipsilateral exfoliative glaucoma. Am J Ophthalmol. 2000. 129:534–536.
8. Ikeda N, Saito T, Hayasaka S, Hayasaka Y. Unilateral symptomatic elevation of intraocular pressure and prevention using a hyperosmotic agent during hemodialysis. Jpn J Ophthalmol. 2001. 45:659–661.
9. Sitprija V, Holmes JH. Preliminary observations on the change in intracranial pressure and intraocular pressure during hemodialysis. Trans Am Soc Artif Intern Organs. 1962. 8:300–308.
10. Sitprija V, Holmes JH, Ellis PP. Changes in intraocular pressure during hemodialysis. Invest Ophthalmol. 1964. 3:273–284.
11. Sitprija V, Holmes JH, Ellis PP. Intraocular pressure change during artificial kidney therapy. Arch Ophthalmol. 1964. 72:626–631.
12. Hojs R, Pahor D. Intraocular pressure in chronic renal failure patients treated with maintenance hemodialysis. Ophthalmologica. 1997. 211:325–326.
13. Tokuyama T, Ikeda T, Sato K. Effect of plasma colloid osmotic pressure on intraocular pressure during hemodialysis. Br J Ophthalmol. 1998. 82:751–753.
14. Jaeger P, Morisod L, Wauters JP, Faggioni R. Prevention of glaucoma during hemodialysis by mannitol and acetazolamide. N Engl J Med. 1980. 303:702.
15. De Marchi S, Cecchin E, Tesio F. Intraocular pressure changes during hemodialysis: prevention of excessive dialytic rise and development of severe metabolic acidosis following acetazolamide therapy. Ren Fail. 1989. 11:117–124.
16. Cecchin E, De Marchi S, Tesio F. Intraocular pressure and hemodialysis. Nephron. 1986. 43:73–74.
17. Tawara A, Kobata H, Fujisawa K, et al. Mechanism of intraocular pressure elevation during hemodialysis. Curr Eye Res. 1998. 17:339–347.
18. Seo SG, Kim YI, Kim YW, Yun IH. A Study of intraocular pressure during hemodialysis in CRF patients. J Korean Ophthalmol Soc. 2002. 43:1222–1229.
19. Levy J, Tovbin D, Lifshitz T, et al. Intraocular pressure during haemodialysis: a review. Eye. 2005. 19:1249–1256.
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