Korean J Radiol.  2009 Oct;10(5):508-510. 10.3348/kjr.2009.10.5.508.

Acute Lymphoblastic Leukemia Presented as Multiple Breast Masses

• Bayrak IK
• Yalin T
• Ozmen Z
• Aksoz T
• Doughanji

• KMID: 1093966
• DOI: http://doi.org/10.3348/kjr.2009.10.5.508

Abstract

Breast metastases in cases leukemia are very rare and occur primarily in patients with acute myeloid leukemia. We report the involvement of breast metastases in a 30-year-old woman with acute T cell lymphoblastic leukemia. The patient's mammograms revealed an extremely dense pattern with ill-defined, denser mass-like lesions in both breasts. A bilateral breast ultrasonographic evaluation revealed lobular-shaped and partly ill-defined hypoechoic masses with a multi-septated nodular (mottled) appearance.

Keyword

Acute lymphoblastic leukemia; Breast metastasis; Mammography; Ultrasonography

MeSH Terms

Adult
Breast Neoplasms/drug therapy/radiography/*secondary/ultrasonography
Diagnosis, Differential
Female
Humans
Mammography
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*pathology
Ultrasonography, Mammary

Figure

• 

  Fig. 1 Acute lymphoblastic leukemia presenting as multiple breast masses in 30-year-old woman. A, B. Mediolateral mammograms show extremely dense pattern with illdefined, denser mass-like lesions located in upper right (A) and left (B) breasts (arrows). C, D. Ultrasonographic images of both breasts show lobular-shaped and partly ill-defined hypoechoic masses with multi-septated nodular (mottled) appearance and no acoustic changes (C: right, D: left). E-H. Following chemotherapy, mammographic densities disappeared (E: right, F: left). Ultrasonographic results concur with no abnormal echoic lesions in both breasts (G: right, H: left).

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