J Vet Sci.  2006 Sep;7(3):297-298. 10.4142/jvs.2006.7.3.297.

Multilobular tumor of the mandible in a Pekingese dog

Affiliations
  • 1Department of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, Seoul 151-742, Korea. daeyong@snu.ac.kr

Abstract

Multilobular tumor of bone detected in a 2.5-year-old male Pekingese dog is reported. Grossly, the neoplasm consisted of multiple, variably sized, gritty, grayish-white to yellow nodules separated by thick collagenous septa. Histologically, these nodules contained multiple lobules of irregularly shaped and sized islands of well-differentiated osteoid and cartilage, separated by anastomosing fibrovascular septa. Chondrocytes and osteocytes were observed in the lacunae and in more osseous islands in the lobule, respectively. These lobules were surrounded by mesenchymal spindle cells. Mitotic figures were not evident. The neoplastic pattern was consistent with that of a multilobular bone tumor. Diagnosis was based on gross and light microscopic findings. The cause of this neoplasm was not determined.

Keyword

dog; mandible; multilobular bone tumor; tumor

MeSH Terms

Animals
Bone Neoplasms/pathology/surgery/*veterinary
Dog Diseases/*pathology/surgery
Dogs
Histocytochemistry/veterinary
Male
Mandible/*pathology/surgery
Osteosarcoma/pathology/surgery/*veterinary

Figure

  • Fig. 1 Note multiple, variably sized, gritty, grayish-white to yellow nodules on cut section of the mandibular mass.

  • Fig. 2 Note multilobular pattern of irregularly shaped and sized cartilaginous or osseous islands separated by mesenchymal cells. H&E stain, bar = 200 µm.

  • Fig. 3 Higher magnification of one of the lobules showing an osseous island with a few osteocytes, H&E stain, bar = 100 µm.


Cited by  1 articles

Multilobular tumour of the caudal cranium causing severe cerebral and cerebellar compression in a dog
Vassilios Psychas, Panayiotis Loukopoulos, Zoe S. Polizopoulou, Georgios Sofianidis
J Vet Sci. 2009;10(1):81-83.    doi: 10.4142/jvs.2009.10.1.81.


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