Korean J Ophthalmol.  2011 Dec;25(6):451-454. 10.3341/kjo.2011.25.6.451.

Presumed Necrotizing Viral Retinitis after Intravitreal Triamcinolone Injection: Case Report

• Han JM
• Ahn J
• Park KH
• Woo SJ

• KMID: 1031195
• DOI: http://doi.org/10.3341/kjo.2011.25.6.451

Abstract

A 56-year-old man presented with anterior chamber inflammation, increased intraocular pressure, peripheral retinal infiltration, and generalized retinal arterial obstruction suggesting acute retinal necrosis five months after intravitreal triamcinolone acetonide injection (IVTA). He was treated with intravenous antiviral agents and aspirin. Shortly after treatment, retinal infiltrations were resolved, and partial recanalization of the obstructed vessel was observed. Viral retinitis may occur as an opportunistic infection following IVTA due to the local immune modulatory effect of the steroid; hence, close observation following IVTA is necessary.

Keyword

Acute retinal necrosis; Herpetic retinitis; Intravitreal injections; Intravitreal triamcinolone acetonide injection

MeSH Terms

Antiviral Agents/therapeutic use
Aspirin/therapeutic use
Drug Therapy, Combination
Humans
Intravitreal Injections
Male
Middle Aged
Opportunistic Infections/*chemically induced/virology
Retinal Necrosis Syndrome, Acute/*chemically induced/virology
Triamcinolone Acetonide/administration & dosage/*adverse effects