Korean J Gastroenterol.  2011 Nov;58(5):288-292. 10.4166/kjg.2011.58.5.288.

Multiple Colonic Metastases from Hepatocellular Carcinoma

Affiliations
  • 1Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. bdye@amc.seoul.kr

Abstract

No abstract available.


MeSH Terms

Carcinoma, Hepatocellular/*pathology/surgery
Catheter Ablation
Colonic Neoplasms/*diagnosis/pathology/*secondary
Colonoscopy
Humans
Liver Neoplasms/*pathology/surgery
Male
Middle Aged
Positron-Emission Tomography
Tomography, X-Ray Computed
Whole Body Imaging

Figure

  • Fig. 1. CT virtual colonoscopy. (A) A 24.5 mm-sized ulcerofungating mass was observed in the proximal descending colon. (B) A 6 mm-sized sessile polyp was also noted in the descending colon. (C) A 15 mm-sized low attenuated nodule suggesting metastatic tumor was noted in the left adrenal gland (arrow). Ulcerofungating mass in the proximal descending colon was also noted (arrowhead).

  • Fig. 2. Colonoscopic findings. (A) An about 25 mm-sized ovoid mass with central ulceration was noted in the proximal descending colon. The mucosa around ulceration showed similar feature compared with normal surrounding colonic mucosa. (B, C) Smaller tumors with similar morphologies with (A) were noted in the hepatic flexure and the descending colon.

  • Fig. 3. Histologic findings of metastatic sarcoid hepatocellular carcinoma. (A) The colonic crypts were normal and tumor cells infiltrating lamina propria were noted (H&E, ×100). (B) The tumor cells which had large, irregular and pale nuclei and spindle shaped cytoplasm were loosely infiltrating the lamina propria (H&E, ×400).(C) The tumor cells infiltrating the lamina propria were positive for vimentin (×100).

  • Fig. 4. The whole body PET showed multifocal hypermetabolic activities on the bones, left adrenal gland, pancreas, mesentery, lymph nodes, left lung, heart, right thigh muscle, and back muscle. This feature was compatible with disseminated metastatic tumors.


Reference

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