J Korean Acad Nurs.  2011 Jun;41(3):344-353. 10.4040/jkan.2011.41.3.344.

Quality of Sleep and Serum Lipid Profile in Patients with Restless Legs Syndrome

• Bak YG
• Park HS

• KMID: 1015484
• DOI: http://doi.org/10.4040/jkan.2011.41.3.344

Abstract

PURPOSE
The purpose of this study was to compare the quality of sleep with the serum lipid profile in patients who have restless legs syndrome (RLS).
METHODS
The data were obtained from 116 patients with RLS through questionnaires and blood sampling.
RESULTS
The results of this study showed correlations between lower quality of sleep and serum lipid profile (LDL Cholesterol) in patients with RLS (r=.19, p=.040). There were correlations for scores of quality of sleep from the, Pittsburgh Sleep Quality Index (PSQI) sub-region between lower subjective sleep quality and serum lipid profile (LDL Cholesterol) (r=.20, p=.026), between fewer hours of sleep duration and serum lipid profile (Total Cholesterol) (r=-.21, p=.024), and, between higher daytime dysfunction and serum lipid profile (LDL Cholesterol) (r=.42, p<.001) of patients with RLS.
CONCLUSION
Patients with RLS have sleep disorders with lower quality of sleep and changes in the serum lipid profile for total cholesterol and LDL cholesterol. That is, patients with RLS have lower quality of sleep and dyslipidemia compared to persons without RLS. Further research is needed to monitor serum the lipid profile in early stage symptoms of midlife adult patients with RLS and especially older women.

Keyword

Restless legs syndrome; Sleep disorders; Dyslipidemia

MeSH Terms

Adult
Aged
Cholesterol, HDL/blood
Cholesterol, LDL/blood
Female
Humans
Lipids/*blood
Male
Middle Aged
Questionnaires
Restless Legs Syndrome/blood/*psychology
*Sleep
Triglycerides/blood

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