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Determinant of Quality of Life in Patients with Chronic Cerebral Infarct

Lee Y, Kim JS, Hong BY, Park JG, Yoo JW, Lee KB, Kim TW, Lim SH

This study investigated how physical and cognitive function and psychological factors affected the health-related quality of life (HRQoL, hereafter HQ) of stroke patients in South Korea. The study enrolled 32...
Treadmill Exercise Ameliorates Chemotherapy-Induced Muscle Weakness and Central Fatigue by Enhancing Mitochondrial Function and Inhibiting Apoptosis

Park SS, Park HS, Jeong H, Kwak HB, No MH, Heo JW, Yoo SZ, Kim TW

PURPOSE: Chemotherapy is associated with the side effects including damage to the mitochondrial DNA. Doxorubicin (DOX) serves as a chemotherapeutic agent for the patients with breast cancer or prostate cancer....
Discontinuation Rate of Doxepin in Insomnia Patients

Lee JH, Kim SM, Hong SC, Seo HJ, Kim TW, Um YH, Jeong JH

OBJECTIVES: We aimed to investigate the discontinuation rate and reasons of doxepin base prescription pattern in insomnia outpatients of psychiatry department of a university hospital. METHODS: 534 patients prescribed doxepin were...
Subtalar Arthroscopy and Posterior Endoscopy

Yoo TW, Ahn JH, Kim J

The application of arthroscopy is becoming increasingly widespread due to the development of surgical instruments and techniques. Subtalar pathology can cause chronic pain in the hindfoot, but it is often...
Multicenter Phase II Study of Oxaliplatin, Irinotecan, and S-1 as First-line Treatment for Patients with Recurrent or Metastatic Biliary Tract Cancer

Yoo C, Han B, Kim HS, Kim KP, Kim D, Jeong JH, Lee JL, Kim TW, Kim JH, Choi DR, Ha HI, Seo J, Chang HM, Ryoo BY, Zang DY

PURPOSE: Although gemcitabine plus cisplatin has been established as the standard first-line chemotherapy for patients with advanced biliary tract cancer (BTC), overall prognosis remains poor. We investigated the efficacy of...
Decreased Expression of Sphingosine-1-Phosphate Receptor 1 in the Blood Leukocyte of Rheumatoid Arthritis Patients

Choi HS, Kim KH, Jin S, Kim J, Yoo I, Pack SP, Ha UH, Park TW, Choi SA, Yuk SH, Kang SW, Jung YW

Sphingosine-1-phosphate (S1P) plays an important role in trafficking leukocytes and developing immune disorders including autoimmunity. In the synovium of rheumatoid arthritis (RA) patients, increased expression of S1P was reported, and...
Body Mass Index as a Predictor of Acute Kidney Injury in Critically Ill Patients: A Retrospective Single-Center Study

Ju S, Lee TW, Yoo JW, Lee SJ, Cho YJ, Jeong YY, Lee JD, Kim JY, Lee GD, Kim HC

BACKGROUND: The aim of this study was to examine the influence of body mass index (BMI) on the development of acute kidney injury (AKI) in critically ill patients in intensive...
Prediction of Treatment Response to Donepezil using Automated Hippocampal Subfields Volumes Segmentation in Patients with Mild Alzheimer's Disease

Um YH, Kim TW, Jeong JH, Seo HJ, Han JH, Hong SC, Lee CU, Lim HK

Previous studies reported some relationships between donepezil treatment and hippocampus in Alzheimer's disease (AD). However, due to methodological limitations, their close relationships remain unclear. The aim of this study is...
Efficacy of Chemotherapy in Patients with Unresectable or Metastatic Pancreatic Acinar Cell Carcinoma: Potentially Improved Efficacy with Oxaliplatin-Containing Regimen

Yoo C, Kim BJ, Kim KP, Lee JL, Kim TW, Ryoo BY, Chang HM

PURPOSE: Pancreatic acinar cell carcinoma (ACC) is a rare cancer of the exocrine pancreas. Because of its rare incidence, the efficacy of chemotherapy in this patient population has been largely...
Outcomes of very elderly (≥ 80 years) critical-ill patients in a medical intensive care unit of a tertiary hospital in Korea

Lee SH, Lee TW, Ju S, Yoo JW, Lee SJ, Cho YJ, Jeong YY, Lee JD, Kim HC

BACKGROUND/AIMS: This study evaluated clinical characteristics and outcomes in very elderly (≥ 80 years of age) critical-ill patients admitted to a medical intensive care unit (MICU) in a regional single...
Erratum to “Prediction of Treatment Response to Donepezil using Automated Hippocampal Subfields Volumes Segmentation in Patients with Mild Alzheimer's Disease”

Um YH, Kim TW, Jeong JH, Seo HJ, Han JH, Hong SC, Lee CU, Lim HK

Unfortunately, the corresponding author's affiliation was incorrect in the original publication of this article..
Sinomenine, an Alkaloid Derived from Sinomenium acutum Potentiates Pentobarbital-Induced Sleep Behaviors and Non-Rapid Eye Movement (NREM) Sleep in Rodents

Yoo JH, Ha TW, Hong JT, Oh KW

Sinomenium acutum has been long used in the preparations of traditional medicine in Japan, China and Korea for the treatment of various disorders including rheumatism, fever, pulmonary diseases and mood...
Medical rehabilitation system for patients in acute rehabilitation units

Yoo SD, Jeong YS, Kim TW

Acute-phase rehabilitation hospitals focus on managing disabilities, reducing sequelae and symptoms, and enhancing social reintegration, to provide patients with the highest possible independence and the best quality of life. In...
Clinical Practice Guideline for Stroke Rehabilitation in Korea 2016

Kim DY, Kim YH, Lee J, Chang WH, Kim MW, Pyun SB, Yoo WK, Ohn SH, Park KD, Oh BM, Lim SH, Jung KJ, Ryu BJ, Im S, Jee SJ, Seo HG, Rah UW, Park JH, Sohn MK, Chun MH, Shin HS, Lee SJ, Lee YS, Park SW, Park YG, Paik NJ, Lee SG, Lee JK, Koh SE, Kim DK, Park GY, Shin YI, Ko MH, Kim YW, Yoo SD, Kim EJ, Oh MK, Chang JH, Jung SH, Kim TW, Kim WS, Kim DH, Park TH, Lee KS, Hwang BY, Song YJ

“Clinical Practice Guideline for Stroke Rehabilitation in Korea 2016” is the 3rd edition of clinical practice guideline (CPG) for stroke rehabilitation in Korea, which updates the 2nd edition published in...
Elevated serum immunoglobulin E level as a marker for progression of immunoglobulin A nephropathy

Lee JH, Lee SY, Kim JS, Kim DR, Jung SW, Jeong KH, Lee TW, Lee YH, Kim YG, Moon JY, Lee SH, Ihm CG

BACKGROUND: Immunoglobulin E (IgE) has traditionally been associated with anaphylaxis and atopic disease. Previous studies reported that serum IgE levels are elevated in nephrotic syndrome and suggested IgE levels as...
A Study of Core Humanistic Competency for Developing Humanism Education for Medical Students

Jung HY, Kim JW, Lee S, Yoo SH, Jeon JH, Kim TW, Park JS, Jeong SY, Oh SJ, Kim EJ, Shin MS

The authors conducted a survey on essential humanistic competency that medical students should have, and on teaching methods that will effectively develop such attributes. The participants consisted of 154 medical...
Knowledge and Perception about Clinical Research Shapes Behavior: Face to Face Survey in Korean General Public

Choi YJ, Beck SH, Kang WY, Yoo S, Kim SY, Lee JS, Burt T, Kim TW

Considering general public as potential patients, identifying factors that hinder public participation poses great importance, especially in a research environment where demands for clinical trial participants outpace the supply. Hence,...
Visual Hallucinations and Amyloid Deposition in Parkinson's Disease Dementia: A Case Report

Um YH, Kim TW, Jeong JH, Seo HJ, Han JH, Hong SC, Jung WS, Choi WH, Lee CU, Lim HK

Parkinson's disease dementia (PDD) is notorious for its debilitating clinical course and high mortality rates. Consequently, various attempts to investigate predictors of cognitive decline in Parkinson's disease (PD) have been...
Rhynchophylline, One of Major Constituents of Uncariae Ramulus et Uncus Enhances Pentobarbital-induced Sleep Behaviors and Rapid Eye Movement Sleep in Rodents

Yoo JH, Ha TW, Hong JT, Oh KW

Rhynchophylline (RP) is a major tetracyclic oxindole alkaloid of Uncariae Ramulus et Uncus which has been used to treat hypertension, seizures, pain and anxiety in the oriental countries. A recent...
Pyrrole-Derivative of Chalcone, (E)-3-Phenyl-1-(2-Pyrrolyl)-2-Propenone, Inhibits Inflammatory Responses via Inhibition of Src, Syk, and TAK1 Kinase Activities

Yang S, Kim Y, Jeong D, Kim JH, Kim S, Son YJ, Yoo BC, Jeong EJ, Kim TW, Han Lee IS, Cho JY

(E)-3-Phenyl-1-(2-pyrrolyl)-2-propenone (PPP) is a pyrrole derivative of chalcone, in which the B-ring of chalcone linked to β-carbon is replaced by pyrrole group. While pyrrole has been studied for possible Src...

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