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A decade of liver organoids: Advances in disease modeling

Liu Y, Sheng JY, Yang CF, Ding J, Chan YS

Liver organoids are three-dimensional cellular tissue models in which cells interact to form unique structures in culture. During the past 10 years, liver organoids with various cellular compositions, structural features,...
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Hospital Utilization and Medication Prescriptions among Patients with Atopic Dermatitis in South Korea: A Real-World Data Analysis

Lee JH, Noh Y, Choi A, Oh IS, Jeon JY, Yoo HJ, Shin JY, Son SW

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ABO Blood Group Antigen Changes in Acute Myeloid Leukemia and No Significant Association With RUNX1 and GATA2 Somatic Variants

Jeong IH, Seo JY, Choi S, Kim HY, Cho D

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Allelic Enhancement of BEL.02 With the Single Nucleotide Variant, c.669G>T

Bae GE, Kim TY, Yu H, Seo JY, Suh JS, Chang SH, Cho D

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Corrigendum to “The Association of Body Mass Index and Waist Circumference with the Risk of Achilles Tendon Problems: A Nationwide Population-Based Longitudinal Cohort Study”

Ahn HS, Kim HJ, Suh JS, Kazmi SZ, Kang TU, Choi JY

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COVID-19 Vaccination Alters NK Cell Dynamics and Transiently Reduces HBsAg Titers Among Patients With Chronic Hepatitis B

Shin H, Lee HS, Noh JY, Koh JY, Kim SY, Park J, Chung SW, Hur MH, Park MK, Lee YB, Kim YJ, Yoon JH, Ko JH, Peck KR, Song JY, Shin EC, Lee JH

Coronavirus disease 2019 (COVID-19) vaccination may non-specifically alter the host immune system. This study aimed to evaluate the effect of COVID-19 vaccination on hepatitis B surface Ag (HBsAg) titer and...
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Major clinical research advances in gynecologic cancer in 2022: highlight on late-line PARP inhibitor withdrawal in ovarian cancer, the impact of ARIEL-4, and SOLO-3

Lee JY, Lee YY, Park JY, Shim SH, Kim SI, Kong TW, Lim CK, Cho HW, Suh DH

In the 2022 series, we summarized the major clinical research advances in gynecologic oncology based on communications at the conference of Asian Society of Gynecologic Oncology Review Course. The review...
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Effectiveness and Safety of COVID-19 Vaccination During Preconceptional and Preclinical Pregnancy Period: A National Population Study

Gwak E, Kim T, Shin JY, Choi NK, Han S, Lee JY, Choe YJ, Choe SA

Background: We aimed to assess the risk of maternal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and early abortive outcomes after the association between coronavirus disease 2019 (COVID-19) vaccination...
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Anti-cancer effect of fenbendazole-incorporated PLGA nanoparticles in ovarian cancer

Chang CS, Ryu JY, Choi JK, Cho YJ, Choi JJ, Hwang JR, Choi JY, Noh JJ, Lee CM, Won JE, Han HD, Lee JW

Objective Fenbendazole (FZ) has potential anti-cancer effects, but its poor water solubility limits its use for cancer therapy. In this study, we investigated the anti-cancer effect of FZ with different drug...
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JAK2 Loss Arising From Tumor-SpreadThrough-Air-Spaces (STAS) Promotes Tumor Progression by Suppressing CD8+ T Cells in Lung Adenocarcinoma: A Machine Learning Approach

Choi S, Kim HS, Min KW, Noh YK, Lee JY, Moon JY, Jung US, Kwon MJ, Kim DH, Son BK, Pyo JS, Ro SK

Background: Tumor spread through air spaces (STAS) is a recently discovered risk factor for lung adenocarcinoma (LUAD). The aim of this study was to investigate specific genetic alterations and anticancer...
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Treatment of Invasive Candida Osteomyelitis of the Mandible: A Case Report

Choi HI, Oh JS, You JS, Moon SY, Choi JY, Park HJ

Osteomyelitis in the oral and maxillofacial area is a relatively uncommon inflammatory disease that occurs due to odontogenic causes such as endodontic infection, facial trauma, insufficient blood supply caused by...
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Spontaneous Uterine Rupture at 22 Weeks’ Gestation in a Woman Who Underwent Abdominal Adenomyomectomy: A Case Report

Lee YR, Chung YE, Hong Jy, Jeong SY, Sung JH, Oh SY, Choi SJ, Roh CR

Uterine rupture during pregnancy, while quite rare, can have devastating consequences for both mother and fetus if it does occur. Uterine surgery is recognized risk factor for uterine rupture during...
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Case of Chronic Active Epstein-Barr Virus Infection Developed Hemophagocytic Lymphohistiocytosis after COVID-19 Infection

Jo S, Jung HL, Lim S, Kim ES, Yang A, Kwak JH, Kim DS, Shim JY, Shim JW

In children, prolonged primary Epstein-Barr virus (EBV) infection or reactivation may lead to the development of T or natural killer cell lymphoproliferative disorders, classified as chronic active EBV infection (CAEBV)....
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Corrigendum to: External Validation of the eCura System for Undifferentiated-Type Early Gastric Cancer with Noncurative Endoscopic Resection

Yang HJ, Kim YI, Ahn JY, Choi KD, Kim SG, Jeon SW, Kim JH, Shin SK, Lee H, Lee WS, Kim GH, Park JM, Shin WG, Choi IJ

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Optical Coherence Tomography Angiography Features of Idiopathic Epiretinal Membrane

Chae, SH, Choi J, Kim JY, Jeon HM, Yoon HS

Purpose: To investigate optical coherence tomography angiography (OCTA) findings in idiopathic epiretinal membrane (ERM) compared with normal controls and analyze postoperative changes. Methods: This retrospective and observational study included 54 eyes...
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Kennedy’s Disease with Chronic Low Back Pain and Muscle Weakness

Kim JY, Park YS, Chang HJ, Park JG, Cho ES, Kim DH, Lee JH, Kim SJ

Kennedy’s disease (KD) or bulbospinal muscular atrophy is an uncommon x-linked recessive genetic disorder. Its diagnosis is challenging due to its wide array of clinical manifestations and difficulty distinguishing it...
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Empiric Anti-Pseudomonal β-Lactam Monotherapy Versus Fluoroquinolone Combination Therapy in Patients With Hospital-Acquired Pneumonia: A Multicenter Cohort Study With Propensity Score Matching

Baek MS, Baek AR, Hong SB, Bae S, Park HK, Kim C, Lee HK, Cho WH, Kim JH, Chang Y, Lee HB, Gil HI, Shin B, Yoo KH, Moon JY, Oh JY, Min KH, Jeon K, on behalf of the Korean HAP/VAP Study Group

Background: There is insufficient data on the benefits of empiric antibiotic combinations for hospital-acquired pneumonia (HAP). We aimed to investigate whether empiric antipseudomonal combination therapy with fluoroquinolones decreases mortality in...
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Treatment Results of Reamed Exchange Nailing in Aseptic Nonunion of Tibial Shaft Fracture

Cho Y, Lee JY, Ryu J, Kim HT, Moon JJ

Purpose: Intramedullary nailing is used widely for treating tibial diaphysis fractures because of its relatively rigid internal fixation, which allows weight bearing, resulting in rapid bone healing and functional recovery....
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Apoptotic effects of hyperoside on FaDu human pharyngeal carcinoma cells

Kang KR, Seo JY, Lim H, Kim JS, Kim DK

Hyperoside (quercetin 3-o-β-d-galactopyranoside) is a flavonoid glycoside with antidepressant, anti-inflammatory, and anti-cancer effects. However, it is not known whether it is effective for oral cancer. This study aimed to investigate...
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Updates of Evidence-Based Nursing Practice Guidelines for Pressure Injury

Kim JY, Park KH, Park OK, Park JH, Lee YJ, Hwang JH

Purpose: This study was conducted to update the previous evidence-based nursing clinical practice guidelines for pressure injury. Methods: The guideline was revised in 22 steps based on the international standards. Results:...
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