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Global Regulators to Activate Silent Biosynthetic Gene Clusters

Shim SH

Genome mining has recently emerged as a powerful strategy to discover novel microbial secondary metabolites. However, more than 50% of biosynthetic gene clusters are not transcribed under standardized laboratory culture...
Advantages of New Endoscopic Unilateral Laminectomy for Bilateral Decompression (ULBD) over Conventional Microscopic ULBD

Kim HS, Choi SH, Shim DM, Lee IS, Oh oK, Woo YH

Background: Biportal endoscopic unilateral laminectomy for bilateral decompression (ULBD) is an emerging minimally invasive procedure for spinal stenosis. However, reports of the results associated with this surgical method are still...
Microsurgical treatment for the recurrent cerebral aneurysm initially treated using coil embolization

Lee J, Kim ST, Shim YW, Back JW, Ko JH, Lee WH, Paeng SH, Pyo SY, Heo YJ, Jeong HW, Jeong YG

Objective: Microsurgical treatment could be a good alternative for the treatment of recurrent cerebral aneurysm after coil embolization. The purpose of this study was to present our experience of microsurgical...
Efficacy and Safety of Rituximab in Korean Patients with Refractory Inflammatory Myopathies

Ahn GY, Suh CH, Kim YG, Park YB, Shim SC, Lee SH, Lee SS, Bae SC, Yoo DH

Background: Rituximab (RTX), a monoclonal antibody that selectively binds to CD20+ B cells, showed favorable outcomes in patients with idiopathic inflammatory myopathies (IIM) in small case series, but the evidence...
Clinical Practice Guideline for Care in the Last Days of Life

Shin J, Chang YJ, Park SJ, Choi JY, Kim SH, Choi YS, Kim NH, Yum HK, Nam EM, Park MH, Moon N, Moon JY, Kang HT, Kang JH, Park JM, Lee CW, Kim SY, Lee EJ, Koh SJ, Kim Y, Agnes Cho M, Song Y, Shim JY

A clinical practice guideline for patients in the dying process in general wards and their families, developed through an evidence-based process, is presented herein. The purpose of this guideline is...
A Case of Successful MitraClip for Severe Mitral Regurgitation with Left Ventricular Dysfunction in Korea

Cha JJ, Hong SJ, Kim JS, Seo J, Lee SH, Lee S, Shim CY, Hong GR

KSNM/KSID/KOSHIC Guidance for Nuclear Medicine Department Against the Coronavirus Disease 2019 (COVID-19) Pandemic

Bang JI, Lee HY, Cho YS, Choi H, Chong A, Eo JS, Kim JY, Kim TS, Kwon HW, Lee EJ, Lee ES, Park HL, Park SB, Shim Hk, Song BI, Yoo ID, Lee KJ, Lee HJ, Han SH, Lee JS, Park JM, Kim SH

The dramatic spread of Coronavirus Disease 2019 (COVID-19) has profound impacts on every continent and life. Due to humanto-human transmission of COVID-19, nuclear medicine staffs also cannot escape the risk...
Efficacy of Buspirone Augmentation of Escitalopram in Patients with Major Depressive Disorder with and without Atypical Features: A Randomized, 8 Week, Multicenter, Open-Label Clinical Trial

Shin C, Ko YH, Shim SH, Kim JS, Na KS, Hahn SW, Lee SH

Objective This study investigated the treatment response and cognitive enhancement effects of buspirone augmentation of escitalopram in patients with major depressive disorder (MDD), according to atypical feature subtypes of MDD. Methods...
Organizing pneumonia as the initial presentation of systemic lupus erythematosus in a Korean adolescent

Kang SY, Kim SY, Choi SH, Sol IS, Kim YH, Shim HS, Lee MJ, Kim KW, Sohn MH

Organizing pneumonia is characterized histologically by the formation of granulation-tissue plugs within the lumens of small airways. It was reported in association with various disorders including infection, drug reactions and...
Correction of the name of author: Pre-implantation genetic diagnosis and pre-implantation genetic screening: two years experience at a single center

Won S, Kim H, Lee WS, Kim JW, Shim SH

Clinical Spectrum of Myelin Oligodendrocyte Glycoprotein-Immunoglobulin G-Associated Disease in Korean Children

Yoo IH, Kim W, Shim Y, Choi SA, Kim SY, Kim H, Lim BC, Hwang H, Choi J, Kim KJ, Kim Y, Hyun JW, Kim SH, Choi K, Kim HJ, Chae JH

Background and Purpose: The myelin oligodendrocyte glycoprotein (MOG) antibody is detected at a high rate in childhood acquired demyelinating syndrome (ADS). This study aimed to determine the diagnostic value of...
Diagnosis and Operation Results for Chronic Lateral Ankle Instability with Subtle Cavovarus Deformity and a Peek-A-Boo Heel Sign

Shim DW, Suh JW, Park KH, Lee JW, Byun J, Han SH

Cavovarus deformity is considered an anatomical risk factor for chronic lateral ankle instability (CLAI). However, subtle deformity can be difficult to detect, and its correction is controversial. The current study...
Panel-Reactive and Donor-Specific Antibodies before Lung Transplantation can Affect Outcomes in Korean Patients Receiving Lung Transplantation

Moon SW, Park MS, Lee JG, Paik HC, Kim YT, Lee HJ, Park S, Choi SM, Kim DH, Cho WH, Yeo HJ, Park Si, Choi SH, Hong SB, Shim TS, Jo KW, Jeon K, Jeong BH, Kim SY, the Korean Organ Transplantation Registry Study Group

Purpose: Data on the distribution and impact of panel reactive antibodies (PRA) and donor specific antibodies (DSA) before lung transplantation in Asia, especially multi-center-based data, are limited. This study evaluated...
Normal Reference Values for Left Atrial Strain and Its Determinants from a Large Korean Multicenter Registry

Sun BJ, Park JH, Lee M, Choi JO, Lee JH, Shin MS, Kim MJ, Jung HO, Park JR, Sohn IS, Kim H, Kim HK, Cho GY, Park JS, Shim CY, Shin SH, Kim KH, Kim WS, Park SW

BACKGROUND: Left atrial (LA) strain is a novel parameter of LA function. However, its reference value has not been established, and the determining factors for LA strain remain elusive. We...
Diagnostic Accuracy and Value of Magnetic Resonance Imaging–Ultrasound Fusion Transperineal Targeted and Template Systematic Prostate Biopsy Based on Bi-parametric Magnetic Resonance Imaging

Noh TI, Tae JH, Kim HK, Shim JS, Kang SG, Sung DJ, Cheon J, Lee JG, Kang SH

Purpose The purpose of this study was to investigate the diagnostic value of magnetic resonance imaging (MRI)–ultrasound (US) fusion transperineal targeted biopsy (FTB) and fusion template systematic biopsy (FSB) for...
Changes in performance of small bowel capsule endoscopy based on nationwide data from a Korean Capsule Endoscopy Registry

Kim SH, Lim YJ, Park J, Shim KN, Yang DH, Chun J, Kim JS, Lee HS, Chun HJ, Research Group for Capsule Endoscopy/Small Bowel Endoscopy

Background/Aims: Capsule endoscopy (CE) is widely used for the diagnosis of small bowel diseases. The clinical performance and complications of small bowel CE, including completion rate, capsule retention rate, and...
Experiences and efficacy of noninvasive prenatal test using maternal plasma in single center: 1,591 cases

Hong SY, Shim SH, Park HJ, Shim SS, Kim JY, Cho YK, Kim SH, Cha DH

Purpose: The objective of this study was to analyze the results of several noninvasive prenatal tests (NIPTs) from a single center and confirm their efficacy and reliability. In addition, we...
The Protective Effect of Ganoderma lucidum Extract in Ultraviolet B-Induced Human Dermal Fibroblasts and Skin Equivalent Models

Lee SH, Lee ES, Bae IH, Kim SH, Park NH, Shim JS, Lee CS, Lee J

Anesthesia-Related Neurally Mediated Syncope in the Perioperative Period: Two Case Reports

Shim JH, Park HJ, Lee CW, Park SH, Hwang YH, Shin WJ, Jeon WJ

The following report describes the occurrence of severe hypotension and bradycardia in a healthy 50-year-old man following placement from supine to the beach chair position during general anesthesia for injured...
Efficacy of Preliminary Magnetic Resonance Imaging Measurement in Ultrasonography-Guided L4 Selective Nerve Root Block

Shim DM, Kweon SH, Cho HG, Yu HK, Lim KH

Purpose: This study examined the utility of preliminary magnetic resonance imaging (MRI) measurements in the ultrasound-guided L4 selective nerve root block. Materials and Methods: As a retrospective study, 71 patients, who...

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