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Inhibition of cell growth and induction of apoptosis by acacetin in FaDu human pharyngeal carcinoma cells

Kang KR, Kim JS, Kim TH, Seo JY, Park JH, Lim JW, Yu SK, Kim HJ, Shin SH, Park BR, Kim CS, Kim DK

Acacetin, which is present in damiana (Turnera diffusa) and black locust (Robinia pseudoacacia), has several pharmacologic activities such as antioxidant, anti-inflammatory, and anti-proliferative effects on cancer cells. However, the effect...
The effect of general health status, oral health behavior and status on quality of life in Korea adults

Jeong HJ, Kim YH, Yun JW, Oh SH, Yoon HS, Lee MK, Lee JH

Objectives: The purpose of this study was to analyze the relations between general health status, oral health behavior, oral health status, and quality of life, as well as the mediating...
Organizing an in-class hackathon to correct PDF-to-text conversion errors of Genomics & Informatics 1.0

Kim S, Kim R, Kim RG, Ko E, Kim HS, Shin J, Cho D, Jin Y, Bae S, Jo YW, Jeong SA, Kim Y, Ahn S, Jang B, Seong J, Lee Y, Seo SE, Kim Y, Kim HJ, Kim H, Sung HL, Lho H, Koo J, Chu J, Lim J, Kim Y, Lee K, Lim Y, Kim M, Hwang S, Han S, Bae S, Kim S, Yoo S, Seo Y, Shin Y, Kim Y, Ko YJ, Baek J, Hyun H, Choi H, Oh JH, Kim DY, Nam HJ, Park HS

This paper describes a community effort to improve earlier versions of the full-text corpus of Genomics & Informatics by semi-automatically detecting and correcting PDF-to-text conversion errors and optical character recognition...
New Paradigm of Pediatric Clinical Clerkship during the Epidemic of COVID-19

Lee YM, Park KD, Seo JH

KR-39038, a Novel GRK5 Inhibitor, Attenuates Cardiac Hypertrophy and Improves Cardiac Function in Heart Failure

Lee JH, Seo HW, Ryu JY, Lim CJ, Yi KY, Oh KS, Lee BH

G protein-coupled receptor kinase 5 (GRK5) has been considered as a potential target for the treatment of heart failure as it has been reported to be an important regulator of...
Risk Factors and Effects of Severe LateOnset Hyponatremia on Long-Term Growth of Prematurely Born Infants

Park JS, Jeong SA, Cho JY, Seo JH, Lim JY, Woo HO, Youn HS, Park CH

Purpose: Sodium is an essential nutritional electrolyte that affects growth. A low serum sodium concentration in healthy premature infants beyond 2 weeks of life is called lateonset hyponatremia (LOH). Here,...
High fat diet accelerates and exacerbates microgliosis and neuronal damage/death in the somatosensory cortex after transient forebrain ischemia in gerbils

Seo WJ, Ahn JH, Lee TK, Kim B, Lee JC, Park JH, Yoo YH, Shin MC, Cho JH, Won MH, Park Y

Obesity has been known as an independent risk factor for stroke. Effects of high-fat diet (HFD)-induced obesity on neuronal damage in the somatosensory cortex of animal models of cerebral ischemia...
Late Onset Nephrogenic Systemic Fibrosis in a Patient with Stage 3 Chronic Kidney Disease: a Case Report

Lim YJ, Bang J, Ko Y, Seo HM, Jung WY, Yi JH, Han SW, Yu My

Nephrogenic systemic fibrosis (NSF) is a progressive systemic fibrosing disease that may occur after gadolinium contrast exposure. It can lead to severe complications and even death. NSF is highly prevalent among...
Recovery of Tenofovir-induced Nephrotoxicity following Switch from Tenofovir Disoproxil Fumarate to Tenofovir Alafenamide in Human Immunodeficiency Virus-Positive Patients

Seo JW, Kim K, Jun KI, Kang CK, Moon SM, Song KH, Bang JH, Kim ES, Kim HB, Park SW, Kim NJ, Choe PG, Park WB, Oh Md

Background: Tenofovir disoproxil fumarate (TDF)-induced nephrotoxicity is related to high plasma tenofovir concentrations. Tenofovir alafenamide (TAF) is a tenofovir prodrug with 90% lower plasma tenofovir concentrations. The aim of this...
A retrospective cytohistological correlation of fine-needle aspiration cytology with classification by the Milan System for Reporting Salivary Gland Cytopathology

Park JH, Cha YJ, Seo JY, Lim JY, Hong SW

Background: Before publication of the new classification system named the Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) in 2018, there was no standard classification for salivary gland lesions obtained...
The clinical usefulness of radiologic report monitoring system of CT and MRI in emergency department: analysis of missed and incidental findings

Lee JH, Seo JS, Lee SC, Lee JH, Do HH, Lee S, Kim YW, Kim JS

  • KMID: 2506066
  • J Korean Soc Emerg Med.
  • 2020 Aug;31(4):391-400.
Objective: This study was undertaken to establish a radiologic report monitoring system (RRMS) for missed and incidental findings (MIFs) in computed tomography (CT) and magnetic resonance imaging (MRI) reports, to...
Effects of alcohol intake on the severity of injuries during riding a bicycle

Seo MJ, Cho JS, Lim YS, Yang HJ, Woo JH, Choi WS

  • KMID: 2506062
  • J Korean Soc Emerg Med.
  • 2020 Aug;31(4):355-361.
Objective: When bike riding under the influence of alcohol, incidence of injury increases, although reports of highly severe injuries is rare. Therefore, this study aimed to determine how drinking alcohol...
Changes in Seroprevalence of Helicobacter pylori Infection over 20 Years in Jinju, Korea, from Newborns to the Elderly

Park JS, Jun JS, Ryu EY, Yeom JS, Park ES, Seo JH, Lim JY, Park CH, Woo HO, Baik SC, Lee WK, Cho MJ, Rhee KH, Youn HS

Background: The objective of this study was to examine changes in the prevalence of cytotoxic-associated gene A (CagA) positive Helicobacter pylori infection in Jinju, Korea, over the last 20 years. Methods:...
Clinical Course and Outcomes of 3,060 Patients with Coronavirus Disease 2019 in Korea, January–May 2020

Sung HK, Kim JY, Heo J, Seo H, Jang Ys, Kim H, Koh BR, Jo N, Oh HS, Baek YM, Park KH, Shon JA, Kim MC, Kim JH, Chang HH, Park Y, Kang YM, Lee DH, Oh DH, Park HJ, Song KH, Lee EK, Jeong H, Lee JY, Ko JY, Choi J, Ryu EH, Chung Kh, Oh Md, The Korea National Committee for Clinical Management of COVID-19

Background: The fatality rate of patients with coronavirus disease 2019 (COVID-19) varies among countries owing to demographics, patient comorbidities, surge capacity of healthcare systems, and the quality of medical care....
Current state of total knee arthroplasty

Seo JH, Lee SH

Total knee arthroplasty (TKA) is a successful and cost-effective treatment for end-stage degenerative arthritis. The aging of society and an increase in the prevalence of obesity has led to increases...
Community-Based Pre-HospitalElectrocardiogram TransmissionProgram for Reducing Systemic TimeDelay in Acute ST-Segment ElevationMyocardial Infarction

Park K, Park JS, Cho YR, Park TH, Kim MH, Yang TH, Kim DI, Kim JH, Lee YH, Lee DW, Seo J, Lee GY, Kim YD

Background and Objectives: In acute ST-segment elevation myocardial infarction (STEMI),on-site transmission of electrocardiogram (ECG) has been shown to reduce systemic timedelay to reperfusion and improve outcomes. However, it has not...
Novel Anti-Inflammatory Effects of Brimonidine on Propionibacterium acnes-Induced Inflammatory Reaction

Choi SR, Yoo JG, Kim SJ, Choi CW, Lee Y, Kim C, Seo YJ, Lee JH, Im M, Park KD

Driving-Related Adverse Events in the Elderly Men: A Population-Based Prospective Cohort Study

Kim JS, Bae JB, Han K, Hong JW, Han JH, Kim TH, Kwak KP, Kim K, Kim BJ, Kim SG, Kim JL, Kim TH, Moon SW, Park JY, Park JH, Byun S, Suh SW, Seo JY, So Y, Ryu SH, Youn JC, Lee KH, Lee DY, Lee DW, Lee SB, Lee JJ, Lee JR, Jeong H, Jeong HG, Jhoo JH, Han JW, Kim KW

Objective This study estimated the incidence of driving-related adverse events and examined the association of cognitive function with the risk of future driving-related adverse events in the elderly Korean male...
Autoimmune encephalitis and epilepsy: evolving definition and clinical spectrum

Seo JH, Lee YJ, Lee KH, Gireesh E, Skinner H, Westerveld M

Advances in autoimmune encephalitis studies in the past 10 years have led to the identification of new syndromes and biomarkers that have transformed the diagnostic approach to the disorder. The...
KSNR Clinical Consensus Statements: Rehabilitation of Patients with Parkinson's Disease

KSNR PD Writing Group, Kim DY, Oh HM, Bok SK, Chang WH, Choi Y, Chun MH, Han SJ, Han TR, Jee S, Jung SH, Jung HY, Jung TD, Kim MW, Kim EJ, Kim HS, Kim YH, Kim Y, Kim DY, Kim DY, Kim DK, Ko SH, Ko MH, Lee JK, Lee J, Lee SJ, Lee SG, Lim SH, Oh BM, Paik NJ, Park KD, Park SW, Park GY, Park JH, Park YG, Pyun SB, Ryu B, Seo HG, Shin YI, Sohn MK, Yang SN, Yoo SD, Yoo WK

Clinical consensus statements (CCSs) aim to improve care for patients with Parkinson's disease (PD) and reduce the variability of rehabilitation methods in clinical practice. A literature search was conducted to...

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