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KR-39038, a Novel GRK5 Inhibitor, Attenuates Cardiac Hypertrophy and Improves Cardiac Function in Heart Failure

Lee JH, Seo HW, Ryu JY, Lim CJ, Yi KY, Oh KS, Lee BH

G protein-coupled receptor kinase 5 (GRK5) has been considered as a potential target for the treatment of heart failure as it has been reported to be an important regulator of...
Characteristics and Trends of Suicide Attempt or Non-suicidal Self-injury in Children and Adolescents Visiting Emergency Department

Kim H, Ryu JM, Kim HW

Background: Non-suicidal self-injury (NSSI) and suicidality are common reasons for child and adolescent psychiatric emergencies. We aimed to investigate the incidence of pediatric emergency department (PED) utilization for psychiatric problems...
Short Course and Early Switch of Vigabatrin for Infantile spasms

Ryu HW, Kim H, Lim BC, Hwang H, Chae JH, Choi JE, Kim KJ

Purpose: Vigabatrin has proven efficacy in the treatment of infantile spasms, but it carries the risk of irreversible visual field constriction. The incidence of vigabatrin-induced visual field constriction seems to...
Effect of Sarcopenia and Body Shape on Cardiovascular Disease According to Obesity Phenotypes

Cho HW, Chung W, Moon S, Ryu OH, Kim MK, Kang JG

Background: This study aimed to assess the effects of sarcopenia and A Body Shape Index (ABSI) on cardiovascular disease (CVD) risk according to obesity phenotypes. Methods: We used data from the...
Prognostic Value of Restaging F-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography to Predict 3-Year Post-Recurrence Survival in Patients with Recurrent Gastric Cancer after Curative Resection

Kim SH, Song BI, Kim HW, Won KS, Son YG, Ryu SW

Objective: The aim of this study was to investigate the prognostic value of the maximum standardized uptake value (SUVmax) measured while restaging with F-18 fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography...
Factors affecting the ability of abdominal ultrasonography to detect focal pancreatic lesions identified using endoscopic ultrasonography

Choi SY, Kim JH, Eun HW, Ryu H

Purpose: This study was conducted to determine which factors influence the ability of abdominal ultrasonography (US) to detect focal pancreatic lesions identified using endoscopic ultrasonography (EUS). Methods: In this study, 338...
Usefulness and Complications of Needle Knife Fistulotomy as a Rescue Procedure in Patients with Pancreaticobiliary Disease

Lee YJ, Kang DH, Kim HW, Park SB, Kim SJ, Nam HS, Ryu DG

Background/Aims: Needle knife fistulotomy (NKF) is a technique to facilitate pancreatic and biliary duct access during ERCP. The double-guidewire technique (DGT) is also used in cases of difficult cannulation, but...
Operative hysteroscopy-assisted pregnancy termination after failed surgical abortion in missed abortion of woman with complete septate uterus

Ryu S, Baek HW, Lee I, Won YB, Kim H, Lee JH, Yun BH, Park JH, Seo SK, Cho S, Choi YS, Lee BS

First trimester surgical abortion is an effective and safe procedure. Although its failure is uncommon, congenital uterine anomaly may be considered as one of the etiologic factors in such cases....
Effect of Renal Denervation on Suppression of PVC and QT Prolongation in a Porcine Model of Acute Myocardial Infarction

Kim SS, Kim HK, Park HW, Jeong MH, Lim KS, Kee HJ, Ryu YH, Kim HB, Na JY, Ki YJ, Park KH, Choi DH, Lee KH, Yoon NS, Cho JG

BACKGROUND AND OBJECTIVES: Antiarrhythmic effect of renal denervation (RDN) after acute myocardial infarction (AMI) remains unclear. The goal of this study was to evaluate the effect of RDN on ventricular...
Methylation Signature for Prediction of Progression Free Survival in Surgically Treated Clear Cell Renal Cell Carcinoma

Kang HW, Park H, Seo SP, Byun YJ, Piao XM, Kim SM, Kim WT, Yun SJ, Jang W, Shon HS, Ryu KH, Lee SC, Kim WJ, Kim YJ

BACKGROUND: Little is known about epigenetic silencing of genes by promoter hypermethylation in renal cell carcinoma (RCC). The aim of this study was to identify prognostic methylation markers in surgically...
Review of National Diagnostic Reference Levels for Interventional Procedures

Lee MY, Kwon J, Ryu GW, Kim KH, Nam HW, Kim KP

Diagnostic reference level (DRL) is employed to optimize the radiation doses of patients. The objective of this study is to review the DRLs for interventional procedures in Korea and abroad....
Incidence of Acute Kidney Injury after Adrenalectomy in Patients with Primary Aldosteronism

Lee JY, Kim H, Kim HW, Ryu GW, Nam Y, Lee S, Joo YS, Lee S, Park JT, Han SH, Kang SW, Yoo TH, Yun HR

BACKGROUND: Aldosterone-induced glomerular hyperfiltration can lead to masked preoperative renal dysfunction in primary aldosteronism(PA) patients. We evaluated whether PA patients had a higher prevalence of acute kidney injury (AKI) after...
Korean National Healthcare-associated Infections Surveillance System, Intensive Care Unit Module Report: Summary of Data from July 2017 through June 2018

Kim EJ, Kwak YG, Kim TH, Lee MS, Lee SO, Kim SR, Park SH, Ahn JY, Yun NR, Ryu SY, Kim ES, Choi JY, Yoo HM, Shin MJ, Yoo SY, Hong KH, Moon HW, Cho NH, Son HJ, Kim SH, Choi YH, Kim MN

BACKGROUND: In this report, we present annual data from the intensive care unit (ICU) module of the Korean National Healthcare-associated Infections Surveillance System (KONIS) from July 2017 through June 2018. METHODS:...
Effect of Institutional Kidney Transplantation Case-Volume on Post-Transplant Graft Failure: a Retrospective Cohort Study

Oh HW, Jang EJ, Kim GH, Yoo S, Lee H, Lim TY, Kim H, Ryu HG

BACKGROUND: The impact of institutional case volume to graft failure rate after adult kidney transplantation is relatively unclear compared to other solid organ transplantations. METHODS: A retrospective cohort study of 13,872...
Estimation of Acute Infarct Volume with Reference Maps: A Simple Visual Tool for Decision Making in Thrombectomy Cases

Kim DE, Ryu WS, Schellingerhout D, Jeong H, Kim P, Jeong SW, Park MS, Choi KH, Kim JT, Kim BJ, Han MK, Lee J, Cha JK, Kim DH, Nah HW, Lee SJ, Kim JG, Hong KS, Cho YJ, Park HK, Lee BC, Yu KH, Oh MS, Park JM, Kang K, Lee KB, Park TH, Park SS, Lee YS, Bae HJ

BACKGROUND AND PURPOSE: Thrombectomy within 24 hours can improve outcomes in selected patients with a clinical-infarct mismatch. We devised an easy-to-use visual estimation tool that allows infarct volume estimation in...
Hand Tremor Questionnaire: A Useful Screening Tool for Differentiating Patients with Hand Tremor between Parkinson's Disease and Essential Tremor

Kwon KY, Ryu HS, Lee HM, Kim MJ, Shin HW, Park HK, You S, Sung YH, Chung SJ, Koh SB

BACKGROUND AND PURPOSE: Hand tremor is one of the most frequent symptoms in movement disorders, and differential diagnoses for hand tremor include Parkinson's disease (PD) and essential tremor (ET). However,...
Nationwide Estimation of Eligibility for Endovascular Thrombectomy Based on the DAWN Trial

Lee KJ, Kim BJ, Kim DE, Ryu WS, Han MK, Kim JT, Choi KH, Cho KH, Cha JK, Kim DH, Nah HW, Park JM, Kang K, Lee SJ, Kim JG, Oh MS, Yu KH, Lee BC, Hong KS, Cho YJ, Park TH, Lee KB, Lee J, Lee JS, Lee J, Bae HJ, Clinical Research Collaboration for Stroke in Korea (CRCS-K) Investigators

No abstract available.
Molecular Identification of Sarcocystis grueneri in Wild Korean Water Deer (Hydropotes inermis argyropus)

Kim HW, Kim HC, Ryu SY, Choi KS, Yu DH, Park J, Chae JS, Park BK

The cysts of Sarcocystis grueneri were detected and characterized from the cardiac muscles of the Korean water deer (Hydropotes inermis argyropus). Of the 38 heart muscle samples examined by light...
Suggestion of Learning Objectives in Social Dental Hygiene: Oral Health Administration Area

Park SK, Lee GY, Jang YE, Yoo SH, Kim YJ, Lee SH, Kim HN, Jo HW, Kim MH, Kim HK, Ryu DY, Kim MJ, Shin SJ, Kim NH, Yoon MS

The purpose of this study is to propose learning objectives in social dental hygiene by analyzing and reviewing learning objectives in oral health administration area of the existing public oral...
CRISPR/Cas9-mediated knockout of CD47 causes hemolytic anemia with splenomegaly in C57BL/6 mice

Kim JI, Park JS, Kwak J, Lim HJ, Ryu SK, Kwon E, Han KM, Nam KT, Lee HW, Kang BC

CD47 (integrin-associated protein), a multi-spanning transmembrane protein expressed in all cells including red blood cells (RBCs) and leukocytes, interacts with signal regulatory protein α (SIRPα) on macrophages and thereby inhibits...

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