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Fucoidan Induces Apoptosis in A2058 Cells through ROS-exposed Activation of MAPKs Signaling Pathway

Ryu YS, Hyun JW, Chung HS

Fucoidan, a natural component of brown seaweed, has various biological activities such as anticancer activity, anti-oxidant, and anti-inflammatory against various cancer cells. However, the fucoidan has been implicated in melanoma...
Vertical Interfragmentary Doubled Suture for Displaced Patella Fractures: Sequential Compressive Tightening with Nice Knot

Lee HJ, Kim BK, Ryu HS, Dan J

In the treatment of displaced patella fractures, open reduction and internal fixation is essential for patellofemoral congruency and restoration of the knee extension mechanism. Various surgical techniques and materials can...
Therapeutic Effect of Levodopa/Carbidopa/Entacapone on Sleep Disturbance in Patients with Parkinson’s Disease

Park KW, Jo S, Lee SH, Hwang YS, Lee D, Ryu HS, Chung SJ

Objective To investigate the efficacy of levodopa/carbidopa/entacapone (LCE) at bedtime for treating sleep disturbance in patients with Parkinson’s disease (PD) with motor fluctuations. Methods Participants included 128 PD patients with motor...
An extremely rare elderly case of proximal epithelioid sarcoma of the vulva: case report with a review of literatures

Jeon SE, Lee J, Jung HJ, Kim BJ, Ryu SY, Park SI, Seol HS, Jang WI, Kim MH

We experienced an extremely rare case of proximal epithelioid sarcoma (PES) of the vulva in a 77-year-old woman. After history taking and physical examination, the patient was tentatively diagnosed as...
Synergistic Induction of Apoptosis by the Combination of an Axl Inhibitor and Auranofin in Human Breast Cancer Cells

Ryu YS, Shin S, An HG, Kwon TU, Baek HS, Kwon YJ, Chun YJ

Axl receptor tyrosine kinase has been implicated in cancer progression, invasion, and metastasis in various cancer types. Axl overexpression has been observed in many cancers, and selective inhibitors of Axl,...
Marginal and internal fit of 3D printed provisional crowns according to build directions

Ryu JE, Kim YL, Kong HJ, Chang HS, Jung JH

PURPOSE. This study aimed to fabricate provisional crowns at varying build directions using the digital light processing (DLP)-based 3D printing and evaluate the marginal and internal fit of the provisional...
Larval Gnathostomes and Spargana in Chinese Edible Frogs, Hoplobatrachus rugulosus, from Myanmar: Potential Risk of Human Infection

Chai JY, Jung BK, Ryu JY, Kim HS, Hong SJ, Htoon TT, Tin HH, Na BK, Sohn WM

Chinese edible frogs, Hoplobatrachus rugulosus, were examined to estimate the potential risks of human gnathostomiasis and sparganosis in Myanmar. A total of 20 frogs were purchased in a local market...
Changes in Seroprevalence of Helicobacter pylori Infection over 20 Years in Jinju, Korea, from Newborns to the Elderly

Park JS, Jun JS, Ryu EY, Yeom JS, Park ES, Seo JH, Lim JY, Park CH, Woo HO, Baik SC, Lee WK, Cho MJ, Rhee KH, Youn HS

Background: The objective of this study was to examine changes in the prevalence of cytotoxic-associated gene A (CagA) positive Helicobacter pylori infection in Jinju, Korea, over the last 20 years. Methods:...
Clinical Course and Outcomes of 3,060 Patients with Coronavirus Disease 2019 in Korea, January–May 2020

Sung HK, Kim JY, Heo J, Seo H, Jang Ys, Kim H, Koh BR, Jo N, Oh HS, Baek YM, Park KH, Shon JA, Kim MC, Kim JH, Chang HH, Park Y, Kang YM, Lee DH, Oh DH, Park HJ, Song KH, Lee EK, Jeong H, Lee JY, Ko JY, Choi J, Ryu EH, Chung Kh, Oh Md, The Korea National Committee for Clinical Management of COVID-19

Background: The fatality rate of patients with coronavirus disease 2019 (COVID-19) varies among countries owing to demographics, patient comorbidities, surge capacity of healthcare systems, and the quality of medical care....
Effects of tranexamic acid on the activity of glutamate transporter EAAT3

Shin HJ, Lee SY, Na HS, Koo BW, Ryu JH, Do SH

Background: Tranexamic acid (TXA) is the most widely used hemostatic agent in surgical patients. However, when used in a high dose, it could cause a seizure in the postoperative period....
KSNR Clinical Consensus Statements: Rehabilitation of Patients with Parkinson's Disease

KSNR PD Writing Group, Kim DY, Oh HM, Bok SK, Chang WH, Choi Y, Chun MH, Han SJ, Han TR, Jee S, Jung SH, Jung HY, Jung TD, Kim MW, Kim EJ, Kim HS, Kim YH, Kim Y, Kim DY, Kim DY, Kim DK, Ko SH, Ko MH, Lee JK, Lee J, Lee SJ, Lee SG, Lim SH, Oh BM, Paik NJ, Park KD, Park SW, Park GY, Park JH, Park YG, Pyun SB, Ryu B, Seo HG, Shin YI, Sohn MK, Yang SN, Yoo SD, Yoo WK

Clinical consensus statements (CCSs) aim to improve care for patients with Parkinson's disease (PD) and reduce the variability of rehabilitation methods in clinical practice. A literature search was conducted to...
Construction reproducibility of a composite tooth model composed of an intraoral-scanned crown and a cone-beam computed tomography-scanned root

Lim SW, Moon RJ, Kim MS, Oh MH, Lee KM, Hwang HS, Kim TW, Baek SH, Cho JH

Objective: To evaluate the construction reproducibility of a composite tooth model (CTM) composed of an intraoral-scanned crown and a cone-beam computed tomography (CBCT)-scanned root. Methods: The study assessed 240 teeth...
Long-Term Expansion of Functional Human Pluripotent Stem Cell-Derived Hepatic Organoids

Mun SJ, Hong YH, Ahn HS, Ryu JS, Chung KS, Son MJ

A human cell-based liver model capable of long-term expansion and mature hepatic function is a fundamental requirement for pre-clinical drug development. We previously established self-renewing and functionally mature human pluripotent...
Clinicopathological Features of Patients with the BRCA1 c.5339T>C (p.Leu1780Pro) Variant

Park HS, Ryu JM, Park JS, Im SA, Jung SY, Kim EK, Park WC, Min JW, Lee J, You JY, Lee JE, Kim SW

Purpose Recent studies revealed the BRCA1 c.5339T>C, p.Leu1780Pro variant (L1780P) is highly suggested as a likely pathogenic. The aim of this study was to evaluate clinicopathologic features of L1780P with breast...
Experimental determination of indoor air concentration of 5-chloro-2-methylisothiazol-3(2H)-one/ 2-methylisothiazol-3(2H)-one (CMIT/MIT) emitted by the use of humidifier disinfectant

Park SK, Seol HS, Park HJ, Kim YS, Ryu SH, Kim J, Kim S, Lee JH, Kwon JH

A mixture of 5-chloro-2-methylisothiazol-3(2H)-one/2-methylisothiazol-3(2H)-one (CMIT/MIT) had been used as an active ingredient in humidifier disinfectants (HDs). Owing to its high reactivity, the atmospheric concentration of CMIT/MIT, following its use in...
Usefulness and Complications of Needle Knife Fistulotomy as a Rescue Procedure in Patients with Pancreaticobiliary Disease

Lee YJ, Kang DH, Kim HW, Park SB, Kim SJ, Nam HS, Ryu DG

Background/Aims: Needle knife fistulotomy (NKF) is a technique to facilitate pancreatic and biliary duct access during ERCP. The double-guidewire technique (DGT) is also used in cases of difficult cannulation, but...
Psychosocial Characteristics and Quality of Life in Patients with Functional Gastrointestinal Disorder

Lee DH, Lee SY, Ryu HS, Choi SC, Yang CM, Jang SH

Objectives:The aim of this study was to compare psychosocial characteristics of the functional gastrointestinal disorders FGID group, non-FGID group, and control group and determine factors affecting the QOL of patients...
Isolated Tongue Deviation in Corona Radiata Infarction

Ryu HS, Kim YW

The Delay in Confirming COVID-19 Cases Linked to a Religious Group in Korea

Kim HJ, Hwang HS, Choi YH, Song HY, Park JS, Yun CY, Ryu S

Objectives: As of March 3, 2020, the Shincheonji religious group accounted for the majority of Korean cases of coronavirus disease 2019 (COVID-19). Nonetheless, the most likely cause of the broad...
Analysis of Genetic Diversity and Population Structure of Wild Strains and Cultivars Using Genomic SSR Markers in Lentinula edodes

Lee HY, Moon S, Ro HS, Chung JW, Ryu H

In this study, the genetic diversity and the population structure of 77 wild strains and 23 cultivars of Lentinula edodes from Korea were analyzed using 20 genomic SSRs, and their...

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