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Estimation of Expected Nursing Hours Based on Patients’ Nursing Care Needs and a Comparison with Actual Nursing Hours in Comprehensive Nursing Care Wards

Cho SH, Hong KJ, Yoon HJ, Chang SJ, Choi K, Park HJ, Huh I

Purpose: To compare actual versus expected nursing hours based on patients’ nursing care needs. Methods: The nursing care needs of 898 inpatients in 20 wards at 11 hospitals were measured...
Next-generation sequencing analysis of exosomal microRNAs: Fusobacterium nucleatum regulates the expression profiling of exosomal microRNAs in human colorectal cancer cells

Yu MR, Kim HJ, Kang JW, Kim YH, Park HR

Colon cancer is one of the most common malignant tumors, but there are still a few validated biomarkers of colon cancer. Exosome-mediated microRNAs (miRNAs) have been recognized as potential biomarkers...
Inhibition of cell growth and induction of apoptosis by acacetin in FaDu human pharyngeal carcinoma cells

Kang KR, Kim JS, Kim TH, Seo JY, Park JH, Lim JW, Yu SK, Kim HJ, Shin SH, Park BR, Kim CS, Kim DK

Acacetin, which is present in damiana (Turnera diffusa) and black locust (Robinia pseudoacacia), has several pharmacologic activities such as antioxidant, anti-inflammatory, and anti-proliferative effects on cancer cells. However, the effect...
Delta-like Factor 1 as a Possible Therapeutic Target for Sarcomas

Kim HS, Ahn SH, Kim HJ, Park JW, Han I

Background: Cancer stem cells (CSCs) are cells characterized by their self-renewal and tumorigenic potential. The purpose of this study was to discover the role of the delta-like factor 1 (DLK1)...
Clinical Guidelines for Drug-induced Peptic Ulcer, 2020 Revised Edition

Joo MK, Park CH, Kim JS, Park JM, Ahn JY, Lee BE, Lee JH, Yang HJ, Cho YK, Bang CS, Kim BJ, Jung HK, Kim BW, Lee YC, Korean College of Helicobacter and Upper Gastrointestinal Research

The Korean guidelines for nonsteroidal anti-inflammatory drug (NSAID)-induced peptic ulcers were previously developed under co-work with the Korean College of Helicobacter and Upper Gastrointestinal Research and Korean Society of Gastroenterology...
“Suicide CARE” (Standardized Suicide Prevention Program for Gatekeeper Intervention in Korea): An Update

Park SC, Na KS, Kwon SJ, Kim M, Kim HJ, Baik M, Seol J, An EJ, Lee SM, Lee EJ, Lim M, Cho SJ, Kim GH, Kim N, Jeon HJ, Paik JW, Oh KS, Lee HY

Objective In 2011, “Suicide CARE” (Standardized Suicide Prevention Program for Gatekeeper Intervention in Korea) was originally developed for the early detection of warning signs of suicide completion, since there is...
Survival and long-term toxicities of pediatric Hodgkin lymphoma after combined modality treatment: a single institute experience

Song KJ, Park Jh, Im HJ, Ahn SD

Purpose: To analyze the clinical outcomes and long-term toxicity of pediatric patients with Hodgkin lymphoma after combined-modality treatment (CMT) with involved-field or involved-nodal radiotherapy (RT). Materials and Methods: We retrospectively reviewed...
Organizing an in-class hackathon to correct PDF-to-text conversion errors of Genomics & Informatics 1.0

Kim S, Kim R, Kim RG, Ko E, Kim HS, Shin J, Cho D, Jin Y, Bae S, Jo YW, Jeong SA, Kim Y, Ahn S, Jang B, Seong J, Lee Y, Seo SE, Kim Y, Kim HJ, Kim H, Sung HL, Lho H, Koo J, Chu J, Lim J, Kim Y, Lee K, Lim Y, Kim M, Hwang S, Han S, Bae S, Kim S, Yoo S, Seo Y, Shin Y, Kim Y, Ko YJ, Baek J, Hyun H, Choi H, Oh JH, Kim DY, Nam HJ, Park HS

This paper describes a community effort to improve earlier versions of the full-text corpus of Genomics & Informatics by semi-automatically detecting and correcting PDF-to-text conversion errors and optical character recognition...
Orbital Space-occupying Congenital Naso-orbital Encephalocele

Kim BY, Kim BR, Kim SI, Cho HJ, Park EK, Yoon JS

Purpose: A case of a huge ethmoid sinus and orbital cyst causing ocular deviation initially diagnosed as a mucocele-like cyst and after orbitotomy eventually discovered to be a naso-orbital encephalocele...
COVID-19 Patients Upregulate Toll-like Receptor 4-mediated Inflammatory Signaling That Mimics Bacterial Sepsis

Sohn KM, Lee SG, Kim HJ, Cheon S, Jeong H, Lee J, Kim IS, Silwal P, Kim YJ, Paik S, Chung C, Park C, Kim YS, Jo EK

Background: Observational studies of the ongoing coronavirus disease 2019 (COVID-19) outbreak suggest that a ‘cytokine storm’ is involved in the pathogenesis of severe illness. However, the molecular mechanisms underlying the altered...
Predictors of Psychiatric Outpatient Adherence after an Emergency Room Visit for a Suicide Attempt

Shin J, Yang S, Park DH, Ryu SH, Ha JH, Kim JW, Jeon HJ

Objective This study aimed to investigate the potential correlation between baseline characteristics of individuals visiting an emergency room for a suicide attempt and subsequent psychiatric outpatient treatment adherence. Methods Medical records...
Anger-Related Characteristics According to Chronotypes in Bipolar or Depressive Disorders

Kang TU, Moon E, Choi Y, Suh H, Park JM, Lee BD, Lee YM, Jeong HJ, Kim SY, Lee K, Lim HJ, Yoon M

Objective Though anger was highly associated with eveningness in general population, there is no study on the relationship between chronotype and anger-related characteristics in bipolar or depressive disorders. This study...
Young-Onset Parkinson’s Disease with Impulse Control Disorder Due to Novel Variants of F-Box Only Protein 7

Yoo D, Choi JH, Im JH, Kim MJ, Kim HJ, Park SS, Jeon B

F-box only protein 7 (FBXO7) is a rare monogenic cause of hereditary Parkinson’s disease (PD) with an autosomal recessive mode of inheritance and a broad spectrum of clinical manifestations. Here,...
Impacts of Remaining Single above the Mean Marriage Age on Mental Disorders and Suicidality: a Nationwide Study in Korea

Lee J, Kim H, Woo J, Chang SM, Hong JP, Lee DW, Hahm BJ, Cho SJ, Park JI, Jeon HJ, Seong SJ, Park JE, Kim BS

Background: This study investigated the impact of getting older than the mean marriage age on mental disorders and suicidality among never-married people. Methods: We performed an epidemiological survey, a nationwide study...
Comparison of Effects of Acute Tabata-Styled and Moderate Intensity Continuous Exercise on Vascular Function in Healthy Young Men

Park IG, Kim YWo, Cho MJ, Kim HJ, Jae SY

Purpose: Regular moderate-intensity aerobic exercise confers immense vascular benefits, yet the lack of time remains the most common barrier to a regular exercise routine. A Tabata exercise is a type...
Prognostic Value of Tumor Regression Grade on MR in Rectal Cancer: A Large-Scale, Single-Center Experience

Yoen H, Park HE, Kim SH, Yoon JH, Hur BY, Bae JS, Kim JH, Oh HJ, Han JK

Objective: To determine the prognostic value of MRI-based tumor regression grading (mrTRG) in rectal cancer compared withpathological tumor regression grading (pTRG), and to assess the effect of diffusion-weighted imaging (DWI)...
Feasibility Study of Synthetic Diffusion-Weighted MRIin Patients with Breast Cancer in Comparison withConventional Diffusion-Weighted MRI

Choi BH, Baek HJ, Ha JY, Ryu KH, Moon JI, Park SE, Bae K, Jeon KN, Jung EJ

Objective: To investigate the clinical feasibility of synthetic diffusion-weighted imaging (sDWI) at different b-values in patientswith breast cancer by assessing the diagnostic image quality and the quantitative measurements compared with...
Follow-Up Intervals for Breast Imaging Reporting andData System Category 3 Lesions on Screening Ultrasoundin Screening and Tertiary Referral Centers

Huh S, Suh HJ, Kim EK, Kim MJ, Yoon JH, Park VY, Moon HJ

Objective: To assess the appropriate follow-up interval, and rate and timepoint of cancer detection in women with Breast ImagingReporting and Data System (BI-RADS) 3 lesions on screening ultrasonography (US) according...
The role of platelet function analyzer-200 in predicting perioperative bleeding risk

Yu ES, Jeon MJ, Kang KW, Lee BH, Kang EJ, Park Y, Lee SR, Sung HJ, Choi CW, Kim BS, Kim DS

Background/Aims: Various preoperative screening tests, such as platelet count, prothrombin time, activated partial thromboplastin time, and bleeding time, have been widely used to evaluate the risk of bleeding during surgery....
Proton pump inhibitor use is associated with hip fracture development: a nationwide populationbased cohort study

Min YW, Lee YC, Kim K, Ryu S, Hong KS, Jeon H, Kim YS, Park JH, Son HJ, Rhee PL

Background/Aims: Effect of proton pump inhibitor (PPI) use on the risk of hip fracture is controversial. This study aimed to clarify the association between PPI use and hip fracture risk using a...

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