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Effect of BMS-470539 on lipopolysaccharide-induced neutrophil activation

Lee S, Ju W, Tin TD, Kim J, Lee JS, Park CH, Kwak SH

Background: BMS-470539, a recently introduced selective agonist of the melanocortin 1 receptor, is known to have anti-inflammatory properties. In this study, we investigated the effects of BMS-470539 on lipopolysaccharide (LPS)-induced...
Fluid intake, hydration status and its association with cognitive function among adolescents in Petaling Perdana, Selangor, Malaysia

Tung SEH, Ch'ng YZ, Karnan TV, Chong PN, Zubaidah JO, Chin YS

BACKGROUND/OBJECTIVES: A cross-sectional study was undertaken to evaluate fluid intake and hydration status in association with cognitive function among 230 adolescents (10–14 years of age) in Petaling Perdana, Selangor, Malaysia. SUBJECTS/METHODS:...
Carpinus turczaninowii extract modulates arterial inflammatory response: a potential therapeutic use for atherosclerosis

Son YK, Yoon SR, Bang WY, Bae CH, Yeo JH, Yeo R, An J, Song J, Kim OY

BACKGROUND/OBJECTIVES: Vascular inflammation is an important feature in the atherosclerotic process. Recent studies report that leaves and branches of Carpinus turczaninowii (C. turczaninowii) have antioxidant capacity and exert anti-inflammatory effects....
Obesity as an independent predictive factor for pathologic complete response after neoadjuvant chemoradiation in rectal cancer

Lee SY, Kim CH, Kim YJ, Kwak HD, Ju JK, Kim HR

PURPOSE: The predictive role of obesity on pathologic complete response (pCR) after neoadjuvant chemoradiation (nCRT) in rectal cancer remains controversial. This study aimed to evaluate the association between obesity and...
Suspicious T1 colon cancer with synchronous liver metastasis not detected by preoperative imaging study

Park CH, Moon SH, Lee HW, Bae SU, Jeong WK, Baek SK

Colorectal carcinoma invading the submucosa but not the muscularis propria (pT1) represents the earliest form of clinically relevant colorectal cancer in most patients. T1 colorectal cancer with synchronous liver metastasis...
Large Thrombosed Right Coronary Artery Aneurysm Mimicking Right Atrial Mass

Tham YC, Yap KH, Ch'ng JK

No abstract available.
Usefulness of the procalcitonin test in young febrile infants between 1 and 3 months of age

Lee IS, Park YJ, Jin MH, Park JY, Lee HJ, Kim SH, Lee JS, Kim CH, Kim YD, Lee JH

PURPOSE: To study the usefulness of the procalcitonin (PCT) test in young febrile infants between 1 and 3 months of age. METHODS: We evaluated the medical records of 336 febrile infants...
Continuing five or more locoregional therapies before living donor salvage liver transplantation for hepatocellular carcinoma is related to poor recurrence-free survival

Rhu J, Kim JM, Choi GS, Kwon CH, Joh JW

PURPOSE: This study was designed to analyze factors related to the success of salvage liver transplantation (SLT) in hepatocellular carcinoma (HCC). While liver resection (LR) is considered the best locoregional...
Plasma Cell-Free DNA as a Predictive Marker after Radiotherapy for Hepatocellular Carcinoma

Park S, Lee EJ, Rim CH, Seong J

PURPOSE: Cell-free DNA (cfDNA) is gaining attention as a novel biomarker for oncologic outcomes. We investigated the clinical significance of cfDNA in hepatocellular carcinoma (HCC) patients treated with radiotherapy (RT). MATERIALS...
Prognostic value of total triiodothyronine and free thyroxine levels for the heart failure in patients with acute myocardial infarction

Kang MG, Hahm JR, Kim KH, Park HW, Koh JS, Hwang SJ, Hwang JY, Ahn JH, Park Y, Jeong YH, Park JR, Kwak CH

BACKGROUND/AIMS: Although a low triiodothyronine (T3) state is closely associated with heart failure (HF), it is uncertain whether total T3 levels on admission is correlated with the clinical outcomes of...
An updated hip fracture projection in Asia: The Asian Federation of Osteoporosis Societies study

Cheung CL, Ang SB, Chadha M, Chow ES, Chung YS, Hew FL, Jaisamrarn U, Ng H, Takeuchi Y, Wu CH, Xia W, Yu J, Fujiwara S

OBJECTIVES: Hip fracture is a major public health problem. Earlier studies projected that the total number of hip fracture will increase dramatically by 2050, and most of the hip fracture...
Nonalcoholic Fatty Liver Disease and Abdominal Fat Accumulation According to Vitamin D Status in Patients with Type 2 Diabetes

Choi DH, Jung CH, Mok JO, Kim CH, Kang SK, Kim BY

BACKGROUND: Vitamin D deficiency is known to increase the incidence of metabolic syndrome. Nonalcoholic fatty liver disease is a common metabolic disease in patients with type 2 diabetes. This study...
Diagnostic Performance of %[-2]proPSA and Prostate Health Index for Prostate Cancer: Prospective, Multi-institutional Study

Park H, Lee SW, Song G, Kang TW, Jung JH, Chung HC, Kim SJ, Park CH, Park JY, Shin TY, Suh IB, Kim JH

BACKGROUND: We evaluated the clinical performance of [-2]proPSA (p2PSA) and its derivatives in predicting the presence and aggressiveness of prostate cancer (PCa) in Korean men. METHODS: A total of 246 men...
Early disseminated recurrence after liver resection in solitary hepatocellular carcinoma

Kim JM, Yi NJ, Kwon CH, Lee KW, Suh KS, Joh JW

PURPOSE: Although few hepatectomy patients develop unexpected early diffuse and multinodular recurrence in the remnant liver, the prognosis in such cases is often dismal. The aim of this study was...
Combined effect of recombinant human bone morphogenetic protein-2 and low level laser irradiation on bisphosphonate-treated osteoblasts

Jeong SY, Hong JU, Song JM, Kim IR, Park BS, Kim CH, Shin SH

OBJECTIVES: The purpose of this study was to evaluate the synergic effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) and low-level laser therapy (LLLT) on bisphosphonate-treated osteoblasts. MATERIALS AND METHODS: Human...
Intravenous Thrombolysis in Patients with Stroke Taking Rivaroxaban Using Drug Specific Plasma Levels: Experience with a Standard Operation Procedure in Clinical Practice

Seiffge DJ, Traenka C, Polymeris , Thilemann , Wagner B, Hert L, Müller MD, Gensicke H, Peters N, Nickel CH, Stippich C, Sutter R, Marsch S, Fisch U, Guzman R, De Marchis GM, Lyrer PA, Bonati LH, Tsakiris D, Engelter S

BACKGROUND AND PURPOSE: Standard operating procedures (SOP) incorporating plasma levels of rivaroxaban might be helpful in selecting patients with acute ischemic stroke taking rivaroxaban suitable for IVthrombolysis (IVT) or endovascular...
Hangover relieving effect of Sanghwang mushroom mycelium cultured in germinated buckwheat

An YJ, Cho SM, Kim MS, Moon HH, Park DS, Jeon NG, Lee Y, Han CH

The present study was performed to evaluate the hangover relieving effect of germinated buckwheat (GB) and Sanghwang mushroom mycelium cultured in GB (SGB). Both GB and SGB showed 1,1-diphenyl-2-picrylhydrazyl radical...
Liver lesions detected in a hepatitis B core total antibody-positive patient masquerading as hepatocellular carcinoma: a rare case of peliosis hepatis and a review of the literature

Tan CH, Soon GS, Kow WC

Peliosis Hepatis (PH) is a rare vascular disorder of the liver, characterized by the presence of cystic blood-filled cavities distributed throughout the hepatic parenchyma. The pathogenesis of PH remains controversial....
Efficacy of Body Weight Reduction on the SGLT2 Inhibitor in People with Type 2 Diabetes Mellitus

Cho HA, Jung YL, Lee YH, Lee YC, Lee JE, Lee SJ, Jeong SJ, Kim CH

BACKGROUND: Dapagliflozin, a sodium-glucose cotransporter-2 inhibitor, reduces hyperglycemia and body weight by inhibiting renal glucose reabsorption. However, only a few studies have demonstrated efficacy of dapagliflozin for type 2 diabetic...
The Risk of Upper Urinary Tract Involvement in Patients With Ketamine-Associated Uropathy

Yee CH, Teoh JY, Lai PT, Leung VY, Chu WC, Lee WM, Tam YH, Ng CF

PURPOSE: The aims of this study were to investigate the prevalence of upper tract involvement in ketamine-associated uropathy, and to determine the predictors of hydronephrosis in patients with a history...

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