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Rab25 augments cancer cell invasiveness through a β1 integrin/EGFR/VEGF-A/Snail signaling axis and expression of fascin

Jeong BY, Cho KH, Jeong KJ, Park YY, Kim JM, Rha SY, Park CG, Mills GB, Cheong JH, Lee HY

  • Exp Mol Med.
  • 2018 Jan;50(1):e435.
  • doi: 10.1038/emm.2017.248
The small GTP-binding protein Rab25 is associated with tumor formation and progression. However, recent studies have shown discordant effects of Rab25 on cancer cell progression depending on cell lineage. In...
Systems Biology Approaches to Decoding the Genome of Liver Cancer

Lee JS, Kim JH, Park YY, Mills GB

  • Cancer Res Treat.
  • 2011 Dec;43(4):205-211.
Molecular classification of cancers has been significantly improved patient outcomes through the implementation of treatment protocols tailored to the abnormalities present in each patient's cancer cells. Breast cancer represents the...

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