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Anti-adipogenic Pregnane Steroid from a Hydractinia-associated Fungus, Cladosporium sphaerospermum SW67

Lee SR, Kang H, Yoo MJ, Yi SA, Beemelmanns C, Lee J, Kim KH

A pregnane steroid, 3α-hydroxy-pregn-7-ene-6,20-dione (1), was isolated from a Hydractinia-associated Cladosporium sphaerospermum SW67 by repetitive column chromatographic separation and highperformance liquid chromatography (HPLC) purification. The planar structure of 1 was...
The role of platelet function analyzer-200 in predicting perioperative bleeding risk

Yu ES, Jeon MJ, Kang KW, Lee BH, Kang EJ, Park Y, Lee SR, Sung HJ, Choi CW, Kim BS, Kim DS

Background/Aims: Various preoperative screening tests, such as platelet count, prothrombin time, activated partial thromboplastin time, and bleeding time, have been widely used to evaluate the risk of bleeding during surgery....
Differential efficacy between stenting and plain balloon angioplasty for femoropopliteal disease with or without total occlusion

Chae IH, Yoon CH, Ko YG, Min PK, Lee JH, Yu CW, Lee SW, Lee SR, Choi SH, Koh YS, Choi D

Background/Aims: Whether the presence of chronic total occlusion (CTO) affects patency after stenting in femoropopliteal lesions is unknown. We determined the effects of plain balloon angioplasty (POBA) in comparison with...
Surgical skin adhesive bond is safe and feasible wound closure method to reduce surgical site infection following minimally invasive colorectal cancer surgery

Lee CS, Han SR, Kye BH, Bae JH, Koh W, Lee IK, Lee DS, Lee YS

Purpose: Minimally invasive colorectal surgery had reduced the rate of surgical site infection. The use of surgical skin adhesive bond (2-octyl cyanoacrylate) for wound closure reduces postoperative pain and provides...
Positivity of Carbapenemase-producing Enterobacteriaceae in Patients Following Exposure within Long-term Care Facilities in Seoul, Korea

Park JJ, Seo YB, Lee J, Eom JS, Song W, Choi YK, Kim SR, Son HJ, Cho NH

Background: Carbapenemase-producing Enterobacteriaceae (CPE) are emerging as a worldwide threat. Long-term care facilities (LTCFs) are considered a reservoir for CPE and play a central role in transmission to acute care...
A Case of Preleukemic Chronic Myeloid Leukemia Following Chemotherapy and Autologous Transplantation for T-lymphoblastic Lymphoma

Choi H, Cho Sr, Yang D, Lee W, Hwang H, Lee HS, Kim DJ, Kim T, Kim MH

Developing Concentration Index of Industrial and Occupational Accidents: The Case of European Countries

Lee Aloop, Chang SR, Suh Y

Background: From only frequency rate of industrial accidents, it is difficult to define the industry composition of accident statistics in a nation. This study aims to propose and develop a...
Epigenetically Upregulated T-Type Calcium Channels Contribute to Abnormal Proliferation of Embryonic Neural Progenitor Cells Exposed to Valproic Acid

Kim JW, Oh HA, Kim SR, Oh MJ, Seung H, Lee SH, Shin SH

Valproic acid is a clinically used mood stabilizer and antiepileptic drug. Valproic acid has been suggested as a teratogen associated with the manifestation of neurodevelopmental disorders, such as fetal valproate...
Assessment of Hand Motor Function in a Non-human Primate Model of Ischemic Stroke

Won J, Yi KS, Choi CH, Jeon CY, Seo J, Kim K, Yeo HG, Park J, Kim YG, Jin YB, Koo BS, Lim KS, Lee S, Kim KJ, Choi WS, Park SH, Kim YH, Huh JW, Lee SR, Cha SH, Lee Y

  • KMID: 2506534
  • Exp Neurobiol.
  • 2020 Aug;29(4):300-313.
  • doi: 10.5607/en20023
Ischemic stroke results from arterial occlusion and can cause irreversible brain injury. A non-human primate (NHP) model of ischemic stroke was previously developed to investigate its pathophysiology and for efficacy...
Prevalence of Tarsal Coalition in the Korean Population: A Single Institution-Based Study

Kim TY, Yoon SH, Ko JH, Lee TH, Yi SR

Purpose: Korean studies on the prevalence of a tarsal coalition are quite rare, and there are very few reports on the prevalence of multipletarsal coalitions among adults in the foreign...
An Outbreak Associated with Sapovirus GI.3 in an Elementary School in Gyeonggi-do, Korea

Cho SR, Yun SJ, Chae SJ, Jung S, Kim JH, Yong KC, Cho EH, Choi W, Lee DY

On October 4, 2018, an outbreak of gastroenteritis associated with sapovirus occurred among elementary school students in Gyeonggi-do, Korea. Epidemiologic studies were conducted in a retrospective cohort approach. Using self-administered...
Effects of Ammonium Chloride on Ozone-induced Airway Inflammation: the Role of Slc26a4 in the Lungs of Mice

Lee JU, Lee HJ, Kim JN, Kim MK, Kim SR, Chang HS, Park CS, Park JS

Background: Exposure to ozone (O3) induces neutrophilic inflammation and goblet cell hyperplasia in humans and experimental animals. Because the solute carrier family 26-member 4 (Slc26a4; pendrin) gene induces mucin production...
Novel Anti-Inflammatory Effects of Brimonidine on Propionibacterium acnes-Induced Inflammatory Reaction

Choi SR, Yoo JG, Kim SJ, Choi CW, Lee Y, Kim C, Seo YJ, Lee JH, Im M, Park KD

Effects of Air Purifiers on Patients with Allergic Rhinitis: a Multicenter, Randomized, Double-Blind, and Placebo-Controlled Study

Park KH, Sim DW, Lee SC, Moon S, Choe E, Shin H, Kim SR, Lee JH, Park HH, Huh D, Park JW

Purpose: Exposure to particulate matter (PM) is a well-known risk factor in the triggering and exacerbation of allergic airway disease. Indoor environments, where people spend most of their time, are...
Clinical Impact of F-18 FDG PET-CT on Biopsy Site Selection in Patients with Suspected Bone Metastasis of Unknown Primary Site

Yoo SW, Chowdhury MSA, Jeon S, Kang SR, Lee C, Jabin Z, Kim J, Cho SG, Song HC, Bom HS, Min JJ, Kwon SY

Purpose We investigated the clinical role of F-18 fluorodeoxyglucose (FDG) positron emission tomography-computed tomography(PET-CT) in the identification of the primary site and the selection of the optimal biopsy site in...
Juvenile Parkinsonism with PARK2 Gene Mutation Misdiagnosed as Dopa-responsive Dystonia: a Case Report

Hong S, Lee S, Cho SR

Parkinson's disease is prevalent in elderly patients, usually aged over 50 years. If clinical symptoms of parkinsonism appear before 21 years of age, it is called juvenile parkinsonism (JP). JP...
Spontaneous Internal Anal Sphincter Relaxation During High-resolution Anorectal Manometry Is Associated With Peripheral Neuropathy and Higher Charlson Comorbidity Scores in Patients With Defecatory Disorders

Lee TH, Lee JS, Kim J, Kim JO, Kim HG, Jeon SR, Hong SJ, Cho YS, Park S

  • KMID: 2504004
  • J Neurogastroenterol Motil.
  • 2020 Jul;26(3):362-369.
  • doi: 10.5056/jnm19129
Background/Aims We aimed to evaluate associations between comorbidities, peripheral neuropathy, and spontaneous internal anal sphincter relaxation (SAR) in patients with defecatory disorders. Methods A patient was considered to exhibit SAR during...
Immature platelet fraction based diagnostic predictive scoring model for immune thrombocytopenia

Jeon MJ, Yu ES, Kang KW, Lee BH, Park Y, Lee SR, Sung HJ, Yoon SY, Choi CW, Kim BS, Kim DS

Background/Aims: The diagnosis of immune thrombocytopenia (ITP) is based on clinical manifestations and there is no gold standard. Thus, even hematologic malignancy is sometimes misdiagnosed as ITP and adequate treatment...
Postoperative Non-Pathological Fever Following Posterior Cervical Fusion Surgery : Is Laminoplasty a Better Preventive Method than Laminectomy?

Lee S, Jung SK, Kim HB, Roh SW, Jeon SR, Park JH

Objective : To analyze the incidence and characteristics of delayed postoperative fever in posterior cervical fusion using cervical pedicle screws (CPS). Methods : This study analyzed 119 patients who underwent posterior...
Clinical experience of immune checkpoint inhibitor for a metastatic jejunal cancer patient with a high tumor mutational burden and low expression of programmed death-ligand 1

Kim SR, Chun SH, Kim JH, Kim SY, Lee BI, Jung CK, Kang JH

Recent data showed that DNA mismatch repair deficiency can be a predictive biomarker for a favorable response of immune checkpoint inhibitors regardless of tumor type due to give rise to...

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