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Food Protein-induced Enterocolitis Mimic king Necrotizing Enterocolitis in a Premature Infant: Case Report

Lee SY, Jo CK, Rha SH, Kim MJ

Food protein-induced enterocolitis (FPIES) is not well documented in newborns. Although FPIES is rare in premature infants, it may occasionally be confused with necrotizing enterocolitis (NEC). This is particularly true...
KRAS, NRAS, and BRAF mutations in plasma cell myeloma at a single Korean institute

Kim Y, Park SS, Min CK, Lee GD, Son J, Jo S, Han E, Han K, Kim M

Background Plasma cell myeloma (PCM) is a genetically heterogeneous disease. The genetic spectrum of PCM has been expanded to mutations such as KRAS, NRAS, and BRAF genes in the RAS-RAF-MAPK pathway....
The health-related quality-of-life of chronic obstructive pulmonary disease patients and disease-related indirect burdens

Choi HS, Yang DW, Rhee CK, Yoon HK, Lee JH, Lim SY, Kim YI, Yoo KH, Hwang YI, Lee SH, Park YB

Background/Aims: Many chronic obstructive pulmonary disease (COPD) patients have physical limitations. We investigated EuroQol five-dimensions five-level (EQ-5D-5L) of COPD patients to assess quality of life, and assessed indirect burden including time...
Impact of previous metronidazole exposure on metronidazole-based second-line quadruple therapy for Helicobacter pylori infection

Lee GH, Lee KM, Shin SJ, Kang JK, Noh CK, Kim JH, Lim SG

Background/Aims: The negative effects on the eradication success of Helicobacter pylori infection after previous exposure to macrolides, including clarithromycin on clarithromycin-based first-line therapy have been demonstrated. However,whether this is...
Usefulness of Ultrasonography in Diagnosis and Management of Tendon Injuries in Hand

Shin CH, Yu SH, Lee CK, Hong HJ, Kim DC, Chung SH

Purpose: Tendon injuries in hand were one of the most frequent injuries caused by trauma. Although consequent tenorrhaphy is frequently conducted, in complete tendon rupture the location of retracted tendon...
Guidelines for Laboratory Diagnosis of Coronavirus Disease 2019 (COVID-19) in Korea

Hong KH, Lee SW, Kim TS, Huh HJ, Lee J, Kim SY, Park JS, Kim GJ, Sung H, Roh KH, Kim JS, Kim HS, Lee ST, Seong MW, Ryoo N, Lee H, Kwon KC, Yoo CK

The outbreak of coronavirus disease 2019 (COVID-19), which began in December 2019, is still ongoing in Korea, with >9,000 confirmed cases as of March 25, 2020. COVID-19 is a severe...
Adjuvanticity of Processed Aloe vera gel for Influenza Vaccination in Mice

Song EJ, Españo E, Nam JH, Kim J, Shim KS, Shin E, Park YI, Lee CK, Kim JK

The effectiveness of current influenza vaccines is considered suboptimal, and 1 way to improve the vaccines is using adjuvants. However, the current pool of adjuvants used in influenza vaccination is...
Long-term Oncologic Outcome of Postoperative Complications After Colorectal Cancer Surgery

Oh CK, Huh JW, Lee YJ, Choi MS, Pyo DH, Lee SC, Park SM, Shin JK, Park YA, Cho YB, Yun SH, Kim HC, Lee WY

Purpose: The impact of postoperative complications on long-term oncologic outcome after radical colorectal cancer surgery is controversial. The aim of this study was to examine the risk factors and oncologic...
Technique of Biportal Endoscopic Transforaminal Lumbar Interbody Fusion

Heo DH, Hong YH, Lee DC, Chung HJ, Park CK

Biportal endoscopic transforaminal lumbar interbody fusion (TLIF) may have advantages of minimally invasive fusion surgery as well as those of endoscopic surgery. The purpose of this study was to present...
A cluster of tertiary transmissions of 2019 novel coronavirus (SARS-CoV-2) in the community from infectors with common cold symptoms

Kim NJ, Choe PG, Park SJ, Lim J, Lee WJ, Kang CK, Park WB, Seong MW, Oh Md

Background/Aims: As the global impact of the novel coronavirus disease 2019 (COVID-19) has been severe, many countries have intensified containment activities to eliminate virus transmission, through early detection and isolation...
Selecting coronavirus disease 2019 patients with negligible risk of progression: early experience from non-hospital isolation facility in Korea

Choe PG, Kang EK, Lee SY, Oh B, Im D, Lee HY, Jung H, Kang CK, Kim MS, Park WB, Choi EH, Cho B, Oh Md, Kim NJ

Background/Aims: As the novel coronavirus (coronavirus disease 2019 [COVID-19]) outbreak progresses rapidly, staying home is recommended for suspected patients; however, the safety of this recommendation is uncertain. In Korea, non-hospital...
Is immunological recovery clinically relevant at 100 days after allogeneic transplantation?

Park J, Lim SH, Kim SH, Yun J, Kim CK, Lee SC, Won JH, Hong DS, Park SK

Background/Aims: Immune reconstitution following allogeneic hematopoietic stem cell transplantation (HSCT) is affected by multiple variables during the transplantation. Methods: We assessed the clinical factors contributing to immune function reconstitution at 100...
Rutin Improves Bone Histomorphometric Values by Reduction of Osteoclastic Activity in Osteoporosis Mouse Model Induced by Bilateral Ovariectomy

Lee HH, Jang JW, Lee JK, Park CK

Objective : Osteoporosis is a disease of unbalanced bone metabolism that results in low bone mineral density with increased bone fragility and propensity for fractures. The increased rate of bone...
Clinical Outcomes of Immune Checkpoint Blocker Therapy for Malignant Melanoma in Korean Patients: Potential Clinical Implications for a Combination Strategy Involving Radiotherapy

Lee J, Chang JS, Roh MR, Jung M, Lee CK, Oh BH, Chung KY, Koom WS, Shin SJ

Purpose We investigated the clinical efficacy of immune checkpoint blocker (ICB) therapy for metastatic or advanced melanoma in Korean patients. As well, we assessed whether the effects of ICBs can be...
Unmet Psychosocial Needs of Patients with Newly Diagnosed Ulcerative Colitis: Results from the Nationwide Prospective Cohort Study in Korea

Moon JR, Lee CK, Hong SN, Im JP, Ye BD, Cha JM, Jung SA, Lee KM, Park DI, Jeen YT, Park YS, Cheon JH, Kim H, Seo B, Kim Y, Kim HJ, the MOSAIK study group of the Korean Association for the Study of Intestinal Diseases (KASID)

Background/Aims: Limited data are available regarding psychosocial distress at the time of diagnosis of ulcerative colitis (UC). We investigated the psychosocial burden and factors related to poor health-related quality of...
Comparison of Effectiveness between Abdominal Vibration Stimulation and Walking Exercise for Bowel Cleansing before Therapeutic Colonoscopy

Noh CK, Kim IS, Lee GH, Park JW, Lee E, Park B, Hong HJ, Lim SG, Shin SJ, Kim JH, Lee KM

Background/Aims: Adequate bowel preparation is important for successful colonoscopy. We aimed to evaluate the clinical feasibility and effectiveness of abdominal vibration stimulation in bowel preparation before therapeutic colonoscopy. Methods: A single...
Baseline Serum Interleukin-6 Levels Predict the Response of Patients with Advanced Non-small Cell Lung Cancer to PD-1/PD-L1 Inhibitors

Kang DH, Park CK, Chung C, Oh IJ, Kim YC, Park D, Kim J, Kwon GC, Kwon I, Sun P, Shin EC, Lee JE

Although various studies on predictive markers in the use of PD-1/PD-L1 inhibitors are in progress, only PD-L1 expression levels in tumor tissues are currently used. In the present study, we...
Clinical experience of immune checkpoint inhibitor for a metastatic jejunal cancer patient with a high tumor mutational burden and low expression of programmed death-ligand 1

Kim SR, Chun SH, Kim JH, Kim SY, Lee BI, Jung CK, Kang JH

Recent data showed that DNA mismatch repair deficiency can be a predictive biomarker for a favorable response of immune checkpoint inhibitors regardless of tumor type due to give rise to...
Prevalence of Carbapenem-Resistant Enterobacteriaceae in Seoul, Korea

Park SH, Kim JS, Kim HS, Yu JK, Han SH, Kang MJ, Hong CK, Lee SM, Oh YH

The prevalence of carbapenem-resistant Enterobacteriaceae (CRE) is increasing globally. However, a few studies have addressed their epidemiology in Seoul, Korea. In this study, we conducted one-year surveillance of CRE among...
Volumetric Assessment of Fusion Mass and Its Clinical Correlations in Posterior Lumbar Interbody Fusion Depending on the Type of Bone Graft

Lee JW, Li QY, Kang KT, Chang BS, Lee CK, Yeom JS, Kim HJ

Study Design: A prospective observational cohort study. Objectives: This study was conducted to analyze associations between the volume of the fusion mass and clinical outcomes 1 year after posterior lumbar interbody...

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