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Changes in Characteristics of Patients with Liver Cirrhosis Visiting a Tertiary Hospital over 15 Years: a Retrospective Multi-Center Study in Korea

Jang WY, Chung WJ, Jang BK, Hwang JS, Lee HJ, Hwang MJ, Kweon YO, Tak WY, Park SY, Lee SH, Lee CH, Kim BS, Kim SH, Suh JI, Park JG

Background: Liver cirrhosis has become a heavy burden not only for patients, but also for our society. However, little is known about the recent changes in clinical outcomes and characteristics...
Daclatasvir and asunaprevir combination therapy for patients with chronic hepatitis C virus genotype 1b infection in real world

Oh JY, Kim BS, Lee CH, Song JE, Lee HJ, Park JG, Hwang JS, Chung WJ, Jang BK, Kweon YO, Tak WY, Park SY, Jang SY, Suh JI, Kwak SG

BACKGROUND/AIMS: Previous studies have reported a high rate of sustained virologic response (SVR) and a low rate of serious adverse events with the use of daclatasvir (DCV) and asunaprevir (ASV)...
Impact of Heart Rate Reduction with Maximal Tolerable Dose of Bisoprolol on Left Ventricular Reverse Remodeling

Choi SW, Han S, Shim WJ, Choi DJ, Kim YJ, Yoo BS, Hwang KK, Jeon HK, Shin MS, Ryu KH

BACKGROUND: We aimed to evaluate effect of heart rate (HR) reduction on left ventricular reverse remodeling (LVRR) in Korean patients with heart failure with reduced ejection fraction (HFrEF). METHODS: Ambulatory patients...
Characteristics of Synchronous and Metachronous Multiple Gastric Tumors after Endoscopic Submucosal Dissection of Early Gastric Neoplasm

Lee HJ, Lee YJ, Lee JY, Kim ES, Chung WJ, Jang BK, Park KS, Hwang JS, Cho KB

BACKGROUND/AIMS: Endoscopic submucosal dissection (ESD) has been widely accepted as a method of treatment of early gastric tumor. This study aimed to identify the incidence and characteristics of multiple gastric...
β-arrestin2 Affects Cardiac Progenitor Cell Survival through Cell Mobility and Tube Formation in Severe Hypoxia

Seo SK, Kim N, Lee JH, Kim SM, Lee SY, Bae JW, Hwang KK, Kim DW, Koch WJ, Cho MC

BACKGROUND AND OBJECTIVES: β-arrestin2 (β-arr2) basically regulates multiple signaling pathways in mammalian cells by desensitization and internalization of G-protein coupled receptors (GPCRs). We investigated impacts of β-arr2 on survival, mobility,...
Masked inherited primary arrhythmia syndromes in sudden cardiac death patients accompanied by coronary vasospasm

Lee KH, Park HW, Eun JN, Cho JG, Yoon NS, Kim MR, Ku YH, Park H, Lee SH, Kim JH, Kim MC, Kim WJ, Kim HK, Cho JY, Park KH, Sim DS, Yoon HJ, Kim KH, Hong YJ, Kim JH, Ahn Y, Jeong MH, Park JC

BACKGROUND/AIMS: Coronary vasospasms are one of the important causes of sudden cardiac death (SCD). Provocation of coronary vasospasms can be useful, though some results may lead to false positives, with...
Prevalence and Density of Digenetic Trematode Metacercariae in Clams and Oysters from Western Coastal Regions of the Republic of Korea

Sohn WM, Na BK, Cho SH, Lee WJ

A survey was performed to know the recent infection status of digenetic trematode metacercariae in clams and oysters from 4 sites in western coastal regions of the Republic of Korea...
The Need for a Well-Organized, Video-Assisted Asthma Education Program at Korean Primary Care Clinics

Kim YH, Yoo KH, Yoo JH, Kim TE, Kim DK, Park YB, Rhee CK, Kim TH, Kim YS, Yoon HK, Um SJ, Park IN, Ryu YJ, Jung JW, Hwang YI, Lee HB, Lim SC, Jung SS, Kim EK, Kim WJ, Lee SS, Lee J, Kim KU, Kim HK, Kim SH, Park JH, Shin KC, Choe KH, Yum HK

BACKGROUND: The purpose of this study was to assess the effect of our new video-assisted asthma education program on patients' knowledge regarding asthma and asthma control. METHODS: Adult asthmatics who were...
Pygidiopsis summa (Digenea: Heterophyidae): Status of Metacercarial Infection in Mullets from Coastal Areas in the Republic of Korea

Sohn WM, Na BK, Cho SH, Lee WJ, Park MY, Lee SW, Choi SB, Huh BN, Seok WS

To know the infection status of zoonotic trematode metacercariae in brackish water fish, we surveyed mullets collected from 18 coastal areas in the Republic of Korea. The metacercariae of Pygidiopsis...
Primary Hepatic Tuberculosis Mimicking Hepatocelluar Carcinoma in Patient with Chronic Viral Hepatitis B and C

Choi SM, Shin KI, Jang BK, Hwang JS, Chung WJ, Kang KJ, Kang YN

Hepatic tuberculosis (TB) is usually associated with pulmonary or miliary TB, but primary hepatic TB is rare less than 1% of all cases of TB. Because hepatic TB lacks typical...
Comparative Effects of Statin Therapy versus Renin-Angiotensin System Blocking Therapy in Patients with Ischemic Heart Failure Who Underwent Percutaneous Coronary Intervention

Won J, Hong YJ, Jeong MH, Park HJ, Kim MC, Kim WJ, Kim HK, Sim DS, Kim JH, Ahn Y, Cho JG, Park JC

Statins and renin-angiotensin system (RAS) blockers are key drugs for treating patients with an acute myocardial infarction (AMI). This study was designed to show the association between treatment with statins...
Survival outcomes of hepatic resection compared with transarterial chemoembolization or sorafenib for hepatocellular carcinoma with portal vein tumor thrombosis

Lee JM, Jang BK, Lee YJ, Choi WY, Choi SM, Chung WJ, Hwang JS, Kang KJ, Kim YH, Chauhan AK, Park SY, Tak WY, Kweon YO, Kim BS, Lee CH

BACKGROUND/AIMS: Treating hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT) remains controversial. We compared the outcomes of hepatic resection (HR), transarterial chemoembolization (TACE), and sorafenib therapy as treatments for...
Predictive factors of mortality within 30 days in patients with nonvariceal upper gastrointestinal bleeding

Lee YJ, Min BR, Kim ES, Park KS, Cho KB, Jang BK, Chung WJ, Hwang JS, Jeon SW

BACKGROUND/AIMS: Nonvariceal upper gastrointestinal bleeding (NVUGIB) is a common medical emergency that can be life threatening. This study evaluated predictive factors of 30-day mortality in patients with this condition. METHODS: A...
A Case of Early Multiply Recurred Hepatocellular Carcinoma after Surgical Resection in Patient Who Unprecedented Chronic Liver Disease

Choi WY, Jang BK, Chung WJ, Hwang JS

Hepatocellular carcinoma (HCC) have relatively well known causative factors such as chronic hepatitis B, chronic hepatitis C, alcoholic liver disease, Non-alcoholic fatty liver disease (NAFLD), liver cirrhosis and so on....
Zoonotic Intestinal Trematodes in Stray Cats (Felis catus) from Riverside Areas of the Republic of Korea

Shin SS, Oh DS, Ahn KS, Cho SH, Lee WJ, Na BK, Sohn WM

The present study was performed to survey the infection status of zoonotic intestinal trematode (ZIT) in stray cats from 5 major riverside areas in the Republic of Korea. Total 400...
Clinical Courses of Primary Hepatic Angiosarcoma: Retrospective Analysis of Eight Cases

Hur CJ, Min BR, Lee YJ, Jang BK, Hwang JS, Kim ES, Park KS, Cho KB, Kang YN, Chung WJ

BACKGROUND/AIMS: Hepatic angiosarcoma, a rare and aggressive liver malignancy, is difficult to diagnose because of a lack of specific clinical features. The clinical and radiological features of patients with histologically...
Predictors of Plaque Progression in Hypertensive Angina Patients with Achieved Low-Density Lipoprotein Cholesterol Less Than 70 mg/dL after Rosuvastatin Treatment

Hong YJ, Jeong MH, Kim MC, Kim WJ, Kim HK, Park KH, Sim DS, Kim JH, Ahn Y, Cho JG, Park JC

We evaluated the impact of achieved low-density lipoprotein cholesterol (LDL-C) concentrations
Shifting Prevalence of Gallbladder Polyps in Korea

Lee YJ, Park KS, Cho KB, Kim ES, Jang BK, Chung WJ, Hwang JS

Only a few studies have evaluated the population-adjusted prevalence of gallbladder polyps (GBP). This study aimed to evaluate the changes in GBP prevalence and risk factors at a single health...
Prevalence of Zoonotic Trematode Metacercariae in Freshwater Fish from Gangwon-do, Korea

Cho SH, Lee WJ, Kim TS, Seok WS, Lee T, Jeong K, Na BK, Sohn WM

The infection status of zoonotic trematode metacercariae was investigated in a total of 2,293 freshwater fish collected from 11 rivers or streams in 9 administrative regions of Gangwon-do, Korea for...
Anti-Inflammatory and Anti-Superbacterial Properties of Sulforaphane from Shepherd's Purse

Choi WJ, Kim SK, Park HK, Sohn UD, Kim W

Shepherd's purse, Capsella bursa-pastoris (L.) Medik., has been considered a health food for centuries in Asia and is known to contain the isothiocyanate compound sulforaphane. In this study, we evaluated...

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