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Serrated Polyposis Syndrome with a Synchronous Colon Adenocarcinoma Treated by an Endoscopic Mucosal Resection

Lee SH, Lee SJ, Park SC, Nam SJ, Kang MH, Kim TS, Lee SK

Serrated polyposis syndrome (SPS) can transform to malignant lesions through the sessile serrated pathway and traditional serrated pathway. These pathways may cause rapid neoplastic progression compared to the adenoma-carcinoma sequence,...
Prognostic Value of Tumor Regression Grade on MR in Rectal Cancer: A Large-Scale, Single-Center Experience

Yoen H, Park HE, Kim SH, Yoon JH, Hur BY, Bae JS, Kim JH, Oh HJ, Han JK

Objective: To determine the prognostic value of MRI-based tumor regression grading (mrTRG) in rectal cancer compared withpathological tumor regression grading (pTRG), and to assess the effect of diffusion-weighted imaging (DWI)...
Characterization of changes in global gene expression in the hearts and kidneys of transgenic mice overexpressing human angiotensin-converting enzyme 2

Lee SH, Jee SW, Hwang DY, Kang JK

Human angiotensin-converting enzyme 2 (hACE2) has recently received a great attention due to it play a critical role as SARS-CoV receptor in the infection of human body. However, no further...
Assessment of Hand Motor Function in a Non-human Primate Model of Ischemic Stroke

Won J, Yi KS, Choi CH, Jeon CY, Seo J, Kim K, Yeo HG, Park J, Kim YG, Jin YB, Koo BS, Lim KS, Lee S, Kim KJ, Choi WS, Park SH, Kim YH, Huh JW, Lee SR, Cha SH, Lee Y

  • KMID: 2506534
  • Exp Neurobiol.
  • 2020 Aug;29(4):300-313.
  • doi: 10.5607/en20023
Ischemic stroke results from arterial occlusion and can cause irreversible brain injury. A non-human primate (NHP) model of ischemic stroke was previously developed to investigate its pathophysiology and for efficacy...
Application of Baveno Criteria and Modified Baveno Criteria with Shear-wave Elastography in Compensated Advanced Chronic Liver Disease

Kang SH, Baik SK, Kim MY

Background: We aimed to validate Baveno VI and expanded Baveno VI criteria using two dimensional shear-wave elastography (2D-SWE) in compensated advanced chronic liver disease (cACLD) patients with alcohol as the...
Hepatocellular carcinoma in old age: are there any benefits of liver resection in old age?

Shin IS, Kim DG, Cha SW, Kang SH, Kim SH, Kim MY, Baik SK

Purpose: Elderly individuals have comorbidities that can adversely affect surgical outcomes. Some studies reported that elderly patients with hepatocellular carcinoma (HCC) have higher liver- and non-liver–related deaths. Therefore, palliative treatments...
Role of CRTC2 in Metabolic Homeostasis: Key Regulator of Whole-Body Energy Metabolism?

Han HS, Kwon Y, Koo SH

Cyclic adenosine monophosphate (cAMP) signaling is critical for regulating metabolic homeostasis in mammals. In particular, transcriptional regulation by cAMP response element-binding protein (CREB) and its coactivator, CREB-regulated transcription coactivator (CRTC),...
Effects of tranexamic acid on the activity of glutamate transporter EAAT3

Shin HJ, Lee SY, Na HS, Koo BW, Ryu JH, Do SH

Background: Tranexamic acid (TXA) is the most widely used hemostatic agent in surgical patients. However, when used in a high dose, it could cause a seizure in the postoperative period....
Application of Segmental Phase Angle for Assessment of Post-Stroke Complex Regional Pain Syndrome

Park SH, Kim WJ, Jo GY, Kwon JK

Our objective is to evaluate the applicability of segmental phase angle (PhA) via bioelectrical impedance analysis (BIA) for post-stroke complex regional pain syndrome (CRPS). Due to its noninvasiveness and convenience,...
A forehead hematoma as the initial clinical sign of lung cancer

Park J, Kang SH, Kim WS, Kim HK, Bae TH

Primary lung cancer commonly metastasizes to the brain, bones, liver, and adrenal glands. In some cases, bone metastasis serves as the first presenting sign of lung cancer with bone pain...
Endometrial profilin 1: a key player in embryo-endometrial crosstalk

Lee CJ, Hong SH, Yoon MJ, Lee KA, Ko JJ, Koo HS, Kim JH, Choi DH, Kwon H, Kang YJ

Objective: Despite extensive research on implantation failure, little is known about the molecular mechanisms underlying the crosstalk between the embryo and the maternal endometrium, which is critical for successful pregnancy....
Eupatilin treatment inhibits transforming growth factor beta-induced endometrial fibrosis in vitro

Lee CJ, Hong SH, Yoon MJ, Lee KA, Choi DH, Kwon H, Ko JJ, Koo HS, Kang YJ

Objective: Endometrial fibrosis, the primary pathological feature of intrauterine adhesion, may lead to disruption of endometrial tissue structure, menstrual abnormalities, infertility, and recurrent pregnancy loss. At present, no ideal therapeutic...
Mesenchymal Stem Cells for the Treatment of Liver Disease: Present and Perspectives

Kang SH, Kim MY, Eom YW, Baik SK

Mesenchymal stem cell transplantation is an emerging therapy for treating chronic liver diseases. The potential of this treatment has been evaluated in preclinical and clinical studies. Although the mechanisms of...
Comparison of Exercise Performance and Clinical Outcome Between Functional Complete and Incomplete Revascularization

Kim J, Lee JM, Choi SH, Choi KH, Park TK, Park SJ, Yang JH, Song YB, Hahn JY, Jang MJ, Koo BK, Gwon HC

BACKGROUND AND OBJECTIVES: Although percutaneous coronary intervention (PCI) is recommended to improve symptoms in patients with stable ischemic heart disease (SIHD), improvement of exercise performance is controversial. This study aimed...
Comparison of Diagnostic Performance of Two-Dimensionaland Three-Dimensional Fractal Dimension and LacunarityAnalyses for Predicting the Meningioma Grade

Kim S, Park YW, Park SH, Ahn SS, Chang JH, Kim SH, Lee SK

Background : To compare the diagnostic performance of two-dimensional (2D) and three-dimensional (3D) fractal dimension (FD) and lacunarity features from MRI for predicting the meningioma grade. Methods : This retrospective study included...
Impact of Multiple Prostate Biopsies: Risk of Perioperative Complications and Biochemical Recurrence After Radical Prostatectomy

Park KM, Chung JW, Kang JK, Shin TJ, Kwon SY, Jang HC, Ha YS, Choi SH, Jung W, Lee JN, Kim BH, Kim BS, Kim HT, Kim JS, Kim TH, Yoo ES, Lee KS, Kim CI, Chung SK, Kwon TG

Purpose: The aim of this study was to analyze the perioperative complications and oncological outcomes of radical prostatectomy (RP) in patients who underwent multiple prostate biopsies. Materials and Methods: A total...
Incidence and Management Trends of Osteoporotic Vertebral Compression Fractures in South Korea: A Nationwide Population-Based Study

Choi SH, Kim DY, Koo JW, Lee SG, Jeong SY, Kang CN

Study Design: A nationwide population-based study. Purpose: Osteoporotic vertebral compression fracture (OVCF) is a major public health issue. This study examined the incidence and management trends of OVCF in South Korea....
Relationships among Family Support, Medical Staff Support, Sick Role Behavior and Physiological Indicators in Hemodialysis Patients

Chae YR, Kang HY, Lee SH, Jo YM, Koo HJ

Background: Family support and medical staff support of hemodialysis patients are related to sick-role behavior, and sick-role behavior is related to physiological indicators such as interdialytic weight gain and control...
Bone Stress Injuries in Runners: a Review for Raising Interest in Stress Fractures in Korea

Song SH, Koo JH

A bone stress injury (BSI) means that the bones cannot tolerate repeated mechanical loads, resulting in structural fatigue and local bone pain. A delay in BSI diagnosis can lead to...
Preoperative Cardiac Computed Tomography Characteristics Associated with Recurrent Aortic Regurgitation after Aortic Valve Re-Implantation

Ahn Y, Koo HJ, Lee S, Kim DH, Song JM, Kang DH, Song JK, Kim HJ, Kim JB, Jung SH, Choo SJ, Chung CH, Lee JW, Kang JW, Yang DH

OBJECTIVE: To identify the preoperative cardiac computed tomography (CT) factors influencing postoperative recurrent aortic regurgitation (AR) in patients who underwent aortic valve repair with the re-implantation technique (David operation) due...

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