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509 results

Prognostic utility of N-terminal pro-B-type natriuretic peptide in adult and elderly patients with community acquired pneumonia

Choi JM, Jeong KY, Choi HS, Hong HP, Lee JS, Ko SH

  • KMID: 2506065
  • J Korean Soc Emerg Med.
  • 2020 Aug;31(4):380-390.
Objective: N-terminal pro-B-type natriuretic peptide (NT-proBNP) is suggested as a prognostic biomarker for communityacquired pneumonia (CAP). However, its predictive value for an individual adult and elderly CAP patients has not...
Comparison of Neuropathological Characteristics between Multiple System Atrophy Cerebellar Type and Parkinsonian Type

Kim EJ, Lee S, Jang SH, Lee MJ, Lee JH, Shin JH, Lee YM, Pak K, Jung NY, Yoon JA, Ko JK, Lee JM, Lee K, Hwang C, Ahn JW, Sung S, Choi KU, Huh GY

Background: Multiple system atrophy (MSA) is a sporadic neurodegenerative disease characterized by various combinations of parkinsonism, cerebellar ataxia, autonomic dysfunction and pyramidal signs. Two clinical subtypes are recognized: MSA with...
ERK Regulates NeuroD1-mediated Neurite Outgrowth via Proteasomal Degradation

Lee Ty, Cho IS, Bashyal N, Naya FJ, Tsai MJ, Yoon JS, Choi JM, Park CH, Kim SS, Suh-Kim H

  • KMID: 2503980
  • Exp Neurobiol.
  • 2020 Jun;29(3):189-206.
  • doi: 10.5607/en20021
Neurogenic differentiation 1 (NeuroD1) is a class B basic helix-loop-helix (bHLH) transcription factor and regulates differentiation and survival of neuronal and endocrine cells by means of several protein kinases, including...
Successful Sirolimus Treatment for Korean Patients with Activated Phosphoinositide 3-kinase δ Syndrome 1: the First Case Series in Korea

Kang JM, Kim SK, Kim D, Choi SR, Lim YJ, Kim SK, Park BK, Park WS, Kang ES, Ko YH, Choe YH, Lee JW, Kim YJ

Activated phosphoinositide 3-kinase δ syndrome (APDS)1 is caused by gain-of-function mutations in PIK3CD, which encodes the catalytic p110δ subunit of phosphoinositide 3 kinase. We describe three patients with APDS1, the...
A Nomogram for Predicting Non-Alcoholic Fatty Liver Disease in Obese Children

Kim A, Yang HR, Cho JM, Chang JY, Moon JS, Ko JS

Purpose: Non-alcoholic fatty liver disease (NAFLD) ranges in severity from simple steatosis to steatohepatitis. Early detection of NAFLD is important for preventing the disease from progressing to become an irreversible...
Management of Acute Stroke Patients Amid the Coronavirus Disease 2019 Pandemic: Scientific Statement of the Korean Stroke Society

Kim BJ, Kim ES, Shin MJ, Kim HB, Lee HY, Hong KS, Park HK, Lee J, Sohn SI, Hwang YH, Ko SB, Park JM, Rha JH, Kwon SU, Kim JS, Heo JH, Lee BC, Yoon BW, Bae HJ

Validation of the Korean Version of the Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease Rating Scale

Choi JH, Lee JY, Cho JW, Ko SB, Ahn TB, Kim SJ, Cheon SM, Kim JS, Kim YJ, Ma HI, Baik JS, Lee PH, Chung SJ, Kim JM, Song IU, Kim HJ, Sung YH, Kwon DY, Lee JH, Kim JY, Kim JS, Yun JY, Kim HJ, Hong JY, Kim MJK, Youn J, Kim JSK, Oh ES, Yang HJ, Yoon WT, You S, Kwon KY, Park HE, Lee SY, Kim Y, Kim HT, Park MY

Background and Purpose Impulse-control disorder is an important nonmotor symptom of Parkinson's disease (PD) that can lead to financial and social problems, and be related to a poor quality of life....
Effect of the Sodium-Glucose Cotransporter 2 Inhibitor, Dapagliflozin, on Genitourinary Infection in an Animal Model of Type 2 Diabetes

Choi JB, Yoo JM, Lee YJ, Kim JW, Lee SJ, Kim HY, Lee DS, Ko SH, Choe HS

Purpose: To investigate the effect of dapagliflozin, a sodium-glucose cotransporter 2 inhibitor, on inflammatory cytokines of urogenital tissue in a rat model of type 2 diabetes (T2DM) to infer pharmaceutical...
Viral Load Kinetics of SARS-CoV-2 Infection in First Two Patients in Korea

Kim JY, Ko JH, Kim Y, Kim YJ, Kim JM, Chung YS, Kim HM, Han MG, Kim SY, Chin BS

As of February 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak started in China in December 2019 has been spreading in many countries in the world. With the numbers...
Effect of intraperitoneally administered propentofylline in a rat model of postoperative pain

Choi GJ, Kang H, Lee JM, Baek CW, Jung YH, Woo YC, Do JH, Ko JS

Background: In this study, we sought to evaluate whether systemic propentofylline (PPF) has antiallodynic effects in a rat model of postoperative pain, and to assess the mechanism involved. Methods: After plantar...
Chemoradiotherapy Alters Protein Expression in Glioblastoma Multiforme

Hwang M, Park HH, Han MH, Choi H, Lee KY, Lee YJ, Kim JM, Cheong JH, Ryu JI, Ko Y, Koh SH

No abstract available.
Mortality Rate and Major Causes of Death by Gestational Age in Korean Children under 5 Years of Age

Jang MJ, Song YH, Yoon JM, Cheon EJ, Ko KO, Lim JW

Background: Preterm birth is associated with increased infant mortality. However, it is not clear whether prematurity is associated with mortality after 1 year of age. There is a lack of...
The Korean Dysphagia Society (KDS) Position Statement for Oropharyngeal Dysphagia

Choi YA, Ko SH, Kim JM, Park Ej, Park JB, Lee Kh, Leigh Jh, Im SH, Cho JH, Han EY, Kim MW

Oropharyngeal dysphagia is a clinical condition caused by various underlying diseases and is characterized by difficulty in swallowing. Diagnosis and treatment of oropharyngeal dysphagia require multidisciplinary consultations. This position statement...
Clinical Implications of Ketosis in Children with Benign Convulsions with Mild Gastroenteritis

Lee JY, Ryu JM, Lee JS, Ko TS, Yum MS

BACKGROUND AND PURPOSE: The pathophysiologic mechanisms underlying benign convulsions with mild gastroenteritis (CwG) in children remain unclear. We investigated the incidence of ketosis in CwG and whether this is related...
Femoral Intertrochanteric Fractures of the Patients in the Emergency Department due to Minor Falls: Special Consideration in the Middle-old to Oldest-old Patients

Jang JM, Choi HS, Lee JS, Jeong KY, Hong HP, Ko SH

BACKGROUND: The older population (≥65 years) has rapidly increased in size in recent years. Among them, the middle-to-oldest-old (≥75 years) tend to have a poor health status. Therefore, subdivision and...
Clinical Relevance for Serum Cold-Inducible RNA-Binding Protein Level in Alopecia Areata

Shin JM, Ko JW, Kwon IS, Choi JW, Hong D, Lee JH, Seo YJ, Kim CD, Lee JH, Lee Y, Park KD

BACKGROUND: Alopecia areata (AA), a chronic, relapsing hair-loss disorder, is considered to be a T-cell-mediated autoimmune disease. Cold-inducible RNA-binding protein (CIRP) belongs to a family of cold-shock proteins that respond...
Surgical Treatment for Displaced Intra-Articular Calcaneal Fractures in Elderly Patients: Comparison of the Minimally Invasive Approach and Extensile Lateral Approach

Park HK, Ko JY, Lee SK, Baik JM

PURPOSE: As the functional demands for activities in elderly patients are increasing according to their life extension, the need for surgical treatment is also increasing in elderly patients with displaced...
The Association Between Obesity and the Nocturia in the U.S. Population

Moon S, Chung HS, Yu JM, Ko KJ, Choi DK, Kwon O, Lee YG, Cho ST

PURPOSE: We aimed to investigate the association of obesity with nocturia using a nationally representative sample of adults from the National Health and Nutrition Examination Survey (NHANES) between 2005 and...
Usefulness of Transient Elastography for Non-Invasive Diagnosis of Liver Fibrosis in Pediatric Non-Alcoholic Steatohepatitis

Kwon YD, Ko KO, Lim JW, Cheon EJ, Song YH, Yoon JM

BACKGROUND: Transient elastography (FibroScan®) is a non-invasive and rapid method for assessing liver fibrosis. While the feasibility and usefulness of FibroScan® have been proven in adults, few studies have focused...
Effect of a Deep Learning Framework-Based Computer-Aided Diagnosis System on the Diagnostic Performance of Radiologists in Differentiating between Malignant and Benign Masses on Breast Ultrasonography

Choi JS, Han BK, Ko ES, Bae JM, Ko EY, Song SH, Kwon MR, Shin JH, Hahn SY

OBJECTIVE: To investigate whether a computer-aided diagnosis (CAD) system based on a deep learning framework (deep learning-based CAD) improves the diagnostic performance of radiologists in differentiating between malignant and benign...

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