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Participation of D-serine and NR2 subunits in EphA4-mediated trigeminal neuropathic pain

Kim MD, Kim MJ, Son JY, Kim YM, Ju JS, Ahn DK

The present study investigated the participation of D-serine and NR2 in antinociception produced by blockade of central erythropoietin-producing hepatocellular carcinoma (Eph) A4 (EphA4) signaling in rats with trigeminal neuropathic pain....
Recovery of Tenofovir-induced Nephrotoxicity following Switch from Tenofovir Disoproxil Fumarate to Tenofovir Alafenamide in Human Immunodeficiency Virus-Positive Patients

Seo JW, Kim K, Jun KI, Kang CK, Moon SM, Song KH, Bang JH, Kim ES, Kim HB, Park SW, Kim NJ, Choe PG, Park WB, Oh Md

Background: Tenofovir disoproxil fumarate (TDF)-induced nephrotoxicity is related to high plasma tenofovir concentrations. Tenofovir alafenamide (TAF) is a tenofovir prodrug with 90% lower plasma tenofovir concentrations. The aim of this...
Clinical Course and Outcomes of 3,060 Patients with Coronavirus Disease 2019 in Korea, January–May 2020

Sung HK, Kim JY, Heo J, Seo H, Jang Ys, Kim H, Koh BR, Jo N, Oh HS, Baek YM, Park KH, Shon JA, Kim MC, Kim JH, Chang HH, Park Y, Kang YM, Lee DH, Oh DH, Park HJ, Song KH, Lee EK, Jeong H, Lee JY, Ko JY, Choi J, Ryu EH, Chung Kh, Oh Md, The Korea National Committee for Clinical Management of COVID-19

Background: The fatality rate of patients with coronavirus disease 2019 (COVID-19) varies among countries owing to demographics, patient comorbidities, surge capacity of healthcare systems, and the quality of medical care....
Clinical Impact of F-18 FDG PET-CT on Biopsy Site Selection in Patients with Suspected Bone Metastasis of Unknown Primary Site

Yoo SW, Chowdhury MSA, Jeon S, Kang SR, Lee C, Jabin Z, Kim J, Cho SG, Song HC, Bom HS, Min JJ, Kwon SY

Purpose We investigated the clinical role of F-18 fluorodeoxyglucose (FDG) positron emission tomography-computed tomography(PET-CT) in the identification of the primary site and the selection of the optimal biopsy site in...
A cluster of tertiary transmissions of 2019 novel coronavirus (SARS-CoV-2) in the community from infectors with common cold symptoms

Kim NJ, Choe PG, Park SJ, Lim J, Lee WJ, Kang CK, Park WB, Seong MW, Oh Md

Background/Aims: As the global impact of the novel coronavirus disease 2019 (COVID-19) has been severe, many countries have intensified containment activities to eliminate virus transmission, through early detection and isolation...
In vitro activity of lopinavir/ritonavir and hydroxychloroquine against severe acute respiratory syndrome coronavirus 2 at concentrations achievable by usual doses

Kang CK, Seong MW, Choi SJ, Kim TS, Choe PG, Song SH, Kim NJ, Park WB, Oh Md

Background/Aims: As the coronavirus disease-2019 global pandemic progresses, screening of antiviral agents effective against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is urgently needed. In addition, considering the viral load...
Selecting coronavirus disease 2019 patients with negligible risk of progression: early experience from non-hospital isolation facility in Korea

Choe PG, Kang EK, Lee SY, Oh B, Im D, Lee HY, Jung H, Kang CK, Kim MS, Park WB, Choi EH, Cho B, Oh Md, Kim NJ

Background/Aims: As the novel coronavirus (coronavirus disease 2019 [COVID-19]) outbreak progresses rapidly, staying home is recommended for suspected patients; however, the safety of this recommendation is uncertain. In Korea, non-hospital...
Successful Pregnancy and Delivery with Intracytoplasmic Sperm Injection in HIV-Serodiscordant Couple: the First Case in Korea

Seong JS, Kim H, Park WB, Kim NJ, Oh Md, Park SS, Park JS, Choi YM

With highly active antiretroviral therapy, human immunodeficiency virus (HIV) infection is considered to be a manageable chronic disease. The improved prognosis increases the desire of individuals with HIV to have...
Surveillance of Chigger Mite Vectors for Tsutsugamushi Disease in the Hwaseong Area, Gyeonggi-do, Republic of Korea, 2015

Bahk YY, Jun H, Park SH, Jung H, Jegal S, Kim-Jeon MD, Roh JY, Lee WG, Ahn SK, Lee J, Joo K, Gong YW, Kwon MJ, Kim TS

Owing to global climate change, the global resurgence of vector-borne infectious diseases and their potential to inflict widespread casualties among human populations has emerged as a pivotal burden on public...
A Case of Breakthrough COVID-19 during Hydroxychloroquine Maintenance

Ahn BY, Kang CK, Seo JD, Choe PG, Song SH, Park WB, Park SW, Kim NJ, Oh Md

There have been controversies on the prophylactic effect of hydroxychloroquine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). We describe a patient, 60-year old Korean woman, with coronavirus disease 2019 (COVID-19)...
The Effect of Bullying Victimization on Depressive Symptoms in Adolescents : Focusing on the Moderating Effects of Resilience

Bae J, Hong H, Kim KM, Jung YE, Kim MD, Yoon BH

Objective : The purpose of this study was to examine the effects of bullying victimization on depressive symptoms in adolescents, and to determine how depression depends on resilience. Methods : A...
Application of carbon dioxide as a novel approach to eradicate poultry red mites

Kang J, Hossain MA, Jeong J, Park H, Kim JH, Kang MS, Kwon YKK, Kim YS, Park SW

Poultry red mites (PRMs), Dermanyssus gallinae, are one of the most harmful ectoparasites of laying hens. Because of their public health impact, safe, effective methods to eradicate PRMs are greatly...
Genotoxicity in Patients on Long-term Proton Pump Inhibitor Therapy in Korea: A Nested Case-control, Prospective, Pilot Study

Choi YI, Chung JW, Park DK, Kim KO, Kwon KA, Kim YJ, Kim SY, Ahn SM, Han MD, Ko KP

Background/Aims: Although proton pump inhibitors (PPIs) remain a mainstay for the suppression of gastric acid secretion, long-term PPI use is associated with side effects. However, the genotoxicity associated with long-term...
Clinical Score System to Differentiate Severe Fever with Thrombocytopenia Syndrome Patients from Patients with Scrub Typhus or Hemorrhagic Fever with Renal Syndrome in Korea

Heo DH, Kang YM, Song KH, Seo JW, Kim JH, Chun JY, Jun KI, Kang CK, Moon SM, Choe PG, Park WB, Bang JH, Kim ES, Kim HB, Park SW, Oh WS, Kim NJ, Oh MD

BACKGROUND: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease with high mortality in East Asia. This study aimed to develop, for primary care providers, a prediction score...
Therapeutic Effect of a Novel Chimeric Molecule Targeting Both Somatostatin and Dopamine Receptors on Growth Hormone-Secreting Pituitary Adenomas

Kim J, Oh JH, Harlem H, Culler MD, Ku CR, Lee EJ

BACKGROUND: Acromegaly is a rare disease primarily caused by growth hormone (GH)-secreting pituitary adenomas, and its treatment is costly. Moreover, some patients are unresponsive to treatment. Hence, there are increasing...
The Influence of Current Mood States on Screening Accuracy of the Mood Disorder Questionnaire

Wang HR, Bahk WM, Yoon BH, Kim MD, Jung YE, Min KJ, Hong J, Woo YS

Objective: In this study we investigated whether current mood states of patients with bipolar disorder have an influence on the screening accuracy of the Mood Disorder Questionnaire (MDQ). Methods: A total...
Virus Isolation from the First Patient with SARS-CoV-2 in Korea

Park WB, Kwon NJ, Choi SJ, Kang CK, Choe PG, Kim JY, Yun J, Lee GW, Seong MW, Kim NJ, Seo JS, Oh MD

Novel coronavirus (SARS-CoV-2) is found to cause a large outbreak started from Wuhan since December 2019 in China and SARS-CoV-2 infections have been reported with epidemiological linkage to China in...
The First Case of 2019 Novel Coronavirus Pneumonia Imported into Korea from Wuhan, China: Implication for Infection Prevention and Control Measures

Kim JY, Choe PG, Oh Y, Oh KJ, Kim J, Park SJ, Park JH, Na HK, Oh MD

In December 2019, a viral pneumonia outbreak caused by a novel betacoronavirus, the 2019 novel coronavirus (2019-nCoV), began in Wuhan, China. We report the epidemiological and clinical features of the...
An Imported Case of Disseminated Echinococcosis in Korea

Shin DH, Jo HC, Kim JH, Jun KI, Park WB, Kim NJ, Choi MH, Kang CK, Oh MD

A complicated case of echinococcosis with multiple organ involvement is reported in a 53-year-old businessman who frequently traveled overseas, including China, Russia, and Kazakhstan from 2001 to 2007. The patient...
Validation of the Korean Version of the Depression in Old Age Scale and Comparison with Other Depression Screening Questionnaires Used in Elderly Patients in Medical Settings

Jung YE, Kim MD, Bahk WM, Woo YS, Nam B, Seo JS, Jang SH, Sung HM, Shim IH, Yoon BH, Kim JS, Kwon YJ

OBJECTIVE: The Depression in Old Age Scale (DIA-S) is a new screening tool for assessing depression in the elderly. The primary aims of this study were to describe the validation...

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