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Neurofibromatosis, Massive Pleural Effusion and Buldging Mass on the Right Chest Wall

Neurofibromatosis is a rare syndrome characterized by abnormal cutaneous pigmentation and numerous skin tumors. Although the syndrome was previously described by Smith in 1849, Von Recklinghausen reported two cases of...
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Stratification of clinical and inflammatory phenotypes according to the urinary leukotriene E4 level in adult asthmatics

Kang S, Jang JH, Jeon HS, Ban GY, Park HS

Purpose: Cysteinyl leukotrienes (CysLTs) have been recognized as key mediators associated with type 2 inflammation in the airways of asthmatic patients. CysLTs are associated with airway constriction, eosinophil recruitment/activation, and...
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Bone Age Estimation and Prediction of Final Adult Height Using Deep Learning

Suh J, Heo J, Kim SJ, Park S, Jung MK, Choi HS, Choi Y, Oh JS, Lee HI, Lee M, Song K, Kwon A, Chae HW, Kim HS

Purpose: The appropriate evaluation of height and accurate estimation of bone age are crucial for proper assessment of the growth status of a child. We developed a bone age estimation...
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A narrative review of scar formation

Han HS, Choi SY, Kim WS, Choi YJ, Yoo KH

A scar is formed through a process in which the damaged skin, including the epidermis and dermis, is filled with abnormal connective tissue because of an imbalance in the response...
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The Effect of Vanishing Twin on Firstand Second-Trimester Maternal Serum Markers and Nuchal Translucency: A Multicenter Prospective Cohort Study

Lee SJ, Han YJ, Kim M, Shim JY, Lee MY, Oh Sy, Lee J, Kim SH, Cha DH, Cho GJ, Kwon HS, Kim BJ, Park MH, Cho HY, Ko HS, Bae JH, Park CW, Park JS, Jun JK, Oh S, Lee DR, Ryu HM, Lee SM

Background: The purpose of this study was to evaluate the effect of vanishing twin (VT) on maternal serum marker concentrations and nuchal translucency (NT). Methods: This is a secondary analysis of...
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Hypersensitivity reactions to ibuprofen and acetaminophen: A report of case with literature review

Yoo MJ, Lee HS, Park JS, Kim JK

The higher the use of nonsteroidal anti-inflammatory drugs (NSAIDs), the more reports of adverse drug reactions, especially in children than in adults. As patients with fever take several NSAIDs alternatively,...
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Quantitative Analysis of Bioactive Compounds in a Mixture of the Lindera glauca Leaves Extract and Water-soluble Mastic Gum using an HPLC/UV Method

Park J, Jang HS, Hong IK, Yang H

This study aimed to establish and validate an HPLC method for the quantitative analysis of bioactive compounds in a mixture of the L. glauca leaves extract and water-soluble mastic gum...
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The Reliability and Validity of a Korean version of the Quality of Life in Life Threatening Illness - Family Carer Version 3: Focused on the families of patients with terminal cancers

Kang KA, Kim HS, Lee MN

Purpose: This study aimed to evaluate the validity and reliability of the Korean version of the Quality of Life in LifeThreatening Illness - Family Carer Version 3 (QOLLTI-F v3) among...
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Changes in Public Health Perceptios after the Outbreak of Coronavirus Disease-19 among the Gangwon Province Residents Focusing on the Results of the Gangwon Province Residents’ Panel Survey 2019-2020

Hwang YS, Jo HS, Jung SM

Objectives: The purpose of this study is to investigate changes in public health-related perceptions of residents of Gangwon province after the outbreak of Coronavirus disease-19(COVID-19) of the public. Methods: We performed...
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Intracranial Pressure Monitoring for Acute Brain Injured Patients: When, How, What Should We Monitor

Shim Y, Kim J, Kim HS, Oh J, Lee S, Ha EJ

While there is no level I recommendation for intracranial pressure (ICP) monitoring, it is typically indicated for patients with severe traumatic brain injury (TBI) with a Glasgow Coma Scale (GCS)...
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Peanut sprout tea extract inhibits lung metastasis of 4T1 murine mammary carcinoma cells by suppressing the crosstalk between cancer cells and macrophages in BALB/c mice

Jung JI, Lee HS, Lee J, Kim EJ

BACKGROUND/OBJECTIVES: As peanuts germinate, the content of the components beneficial to health, such as resveratrol, increases within the peanut sprout. This study examined whether the ethanol extract of peanut sprout...
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Korea Seroprevalence Study of Monitoring of SARS-COV-2 Antibody Retention and Transmission (K-SEROSMART): findings from national representative sample

Han J, Baek HJ, Noh E, Yoon K, Kim JA, Ryu S, Lee KO, Park NY, Jung E, Kim S, Lee H, Hwang YS, Jung J, Lee HJ, Cho Si, Oh S, Kim M, Oh CM, Yu B, Hong YS, Kim K, Jung S, Han MA, Lee MS, Lee JJ, Hwangbo Y, Yim HW, Kim YM, Lee J, Lee WY, Park JH, Oh S, Jo HS, Kim H, Kang G, Nam HS, Lee JH, Oh GJ, Shin MH, Ryu S, Hwang TY, Park SW, Kim SK, Seol R, Park KS, Kim SY, Kwon Jw, Kim SS, Kim B, Lee JW, Jang EY, Kim AR, Nam J, The Korea Community Health Survey Group, Lee SY, Kim DH

OBJECTIVES: We estimated the population prevalence of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), including unreported infections, through a Korea Seroprevalence Study of Monitoring of SARS-CoV-2 Antibody Retention...
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Comparison of Nasal Swabs, Nasopharyngeal Swabs, and Saliva Samples for the Detection of SARS-CoV-2 and other Respiratory Virus Infections

Jung EJ, Lee SK, Shin SH, Kim JS, Woo H, Cho EJ, Hyun J, Kim JS, Kim HS

Background: Nasal swabs and saliva samples are being considered alternatives to nasopharyngeal swabs (NPSs) for detecting severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2); however, few studies have compared the usefulness of...
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Efficacy of Oxygen Treatment Using Home Oxygen Concentrators for the Treatment of Cluster Headaches: A Randomized, Crossover, Multicenter Study

Cho S, Kim BK, Chu MK, Moon HS, Lee MJ, Bae DW, Han J, Lee SH, Cho SJ

Background and Purpose Oxygen treatment is the first-line acute treatment for cluster headaches (CHs), but this can be impeded by insurance coverage and oxygen-tank maintenance. Oxygen concentrators filter nitrogen from...
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Optimizing Mannitol Use in Managing Increased Intracranial Pressure: A Comprehensive Review of Recent Research and Clinical Experiences

Kim JH, Jeong H, Choo YH, Kim M, Ha EJ, Oh J, Shim Y, Kim SB, Jung HG, Park SH, Kim JO, Kim J, Kim HS, Lee S

Mannitol, derived from mannose sugar, is crucial in treating patients with elevated intracranial pressure (ICP). Its dehydrating properties at the cellular and tissue levels increase plasma osmotic pressure, which is...
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JAK2 Loss Arising From Tumor-SpreadThrough-Air-Spaces (STAS) Promotes Tumor Progression by Suppressing CD8+ T Cells in Lung Adenocarcinoma: A Machine Learning Approach

Choi S, Kim HS, Min KW, Noh YK, Lee JY, Moon JY, Jung US, Kwon MJ, Kim DH, Son BK, Pyo JS, Ro SK

Background: Tumor spread through air spaces (STAS) is a recently discovered risk factor for lung adenocarcinoma (LUAD). The aim of this study was to investigate specific genetic alterations and anticancer...
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An Analysis of the Determinants of the Health-Related Quality of Life in Asian Patients With Cluster Headaches During Cluster Periods Using the Time Trade-Off Method

Kim SK, Chu MK, Kim BK, Chung PW, Moon HS, Lee MJ, Choi YJ, Park JW, Kim BS, Song TJ, Oh K, Ahn JY, Sohn JH, Lee KS, Park KY, Chung JM, Chung CS, Cho SJ

Background and Purpose Patients with cluster headache (CH) exhibit impaired health-related quality of life (HRQoL). However, there have been few studies related to the HRQoL of patients with CH from...
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Prevalence and Associated Factors of Depression and Anxiety Among Healthcare Workers During the Coronavirus Disease 2019 Pandemic: A Nationwide Study in Korea

Lee S, Hwang S, Kwon KT, Nam E, Chung US, Kim SW, Chang HH, Kim Y, Bae S, Shin JY, Bae Sg, Ryoo HW, Jeong J, Oh N, Lee SH, Kim Y, Kang CK, Park HY, Park J, Park SY, Kim B, Cheong HS, Son JW, Lim SJ, Yun S, Oh WS, Park KH, Lee JY, Heo ST, Lee Jy

Background: A healthcare system’s collapse due to a pandemic, such as the coronavirus disease 2019 (COVID-19), can expose healthcare workers (HCWs) to various mental health problems. This study aimed to...
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Early Prediction of Mortality for Septic Patients Visiting Emergency Room Based on Explainable Machine Learning: A Real-World Multicenter Study

Park SW, Yeo NY, Kang S, Ha T, Kim TH, Lee D, Kim D, Choi S, Kim M, Lee D, Kim D, Kim WJ, Lee SJ, Heo YJ, Moon DH, Han SS, Kim Y, Choi HS, Oh DK, Lee SY, Park M, Lim CM, Heo J, obotKSA(I

Background: Worldwide, sepsis is the leading cause of death in hospitals. If mortality rates in patients with sepsis can be predicted early, medical resources can be allocated efficiently. We constructed...
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Prognostic Implication of Platelet Reactivity According to Left Ventricular Systolic Dysfunction Status in Patients Treated With Drug-Eluting Stent Implantation: Analysis of the PTRG-DES Consortium

Han D, Kim SH, Shin DG, Kang MK, Choi S, Lee N, Kim BK, Joo HJ, Chang K, Park Y, Song YB, Ahn SG, Suh JW, Lee SY, Her AY, Jeong YH, Kim HS, Kim MH, Lim DS, Shin ES, Cho JR, ftPI

Background: Coronary artery disease patients undergoing percutaneous coronary intervention (PCI) often exhibit reduced left ventricular ejection fraction (LVEF). However, the impact of LV dysfunction status in conjunction with platelet reactivity...
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