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Clinical Practice Guideline for Care in the Last Days of Life

Shin J, Chang YJ, Park SJ, Choi JY, Kim SH, Choi YS, Kim NH, Yum HK, Nam EM, Park MH, Moon N, Moon JY, Kang HT, Kang JH, Park JM, Lee CW, Kim SY, Lee EJ, Koh SJ, Kim Y, Agnes Cho M, Song Y, Shim JY

A clinical practice guideline for patients in the dying process in general wards and their families, developed through an evidence-based process, is presented herein. The purpose of this guideline is...
Concomitant Use of NSAIDs or SSRIs with NOACs Requires Monitoring for Bleeding

Lee MT, Park KY, Kim MS, You SH, Kang YJ, Jung SY

Purpose: Non-vitamin K antagonist oral anticoagulants (NOACs) are widely used in patients with atrial fibrillation (AF) because of their effectiveness in preventing stroke and their better safety, compared with warfarin....
miR-4463 regulates aromatase expression and activity for 17β-estradiol synthesis in response to follicle-stimulating hormone

Lee SY, Kang YJ, Kwon J, Nishi Y, Yanase T, Lee KA, Koong MK

Objective The aim of this study was to investigate microRNAs (miRNAs) related to follicle-stimulating hormone (FSH) responsiveness using miRNA microarrays and to identify their target genes to determine the molecular...
Differential Diagnosis and Treatment Outcomes of Tumors at the Carotid Bifurcation

Kang J, Heo SH, Park YJ, Kim DI, Kim YW

Purpose: Primary tumor at the carotid bifurcation is uncommon, which includes paraganglioma, schwannoma, and lymphoma. Due to their rarity, characteristics of these tumors and problems related to their surgical treatment...
Epidemiological Study of Hereditary Hemolytic Anemia in the Korean Pediatric Population during 1997–2016: a Nationwide Retrospective Cohort Study

Shim YJ, Jung HL, Shin HY, Kang HJ, Choi JY, Hah JO, Lee JM, Lim YT, Yang EJ, Baek HJ, Choi HS, Yoo KH, Park JE, Kim S, Kim JY, Park ES, Im HJ, Chueh HW, Kim SK, Lee JH, Yoo ES, Park HJ, Lee JA, Park M, Kang HS, Park JK, Lee NH, Park SK, Lee YH, Lee SW, Choi EJ, Kong SG

Background: Hereditary hemolytic anemia (HHA) is a rare disease characterized by premature red blood cell (RBC) destruction due to intrinsic RBC defects. The RBC Disorder Working Party of the Korean...
A Case of Simultaneous Active Transcutaneous Bone Conduction Implantation (BonebridgeTM) Performed with Subtotal Petrosectomy

Han JS, Park JM, Kang YJ, Park SN

Subtotal petrosectomy (STP) is an effective treatment modality for recurrent suppurative otitis media (CSOM) and cochlear implant (CI) may be combined for auditory rehabilitation. An active transcutaneous bone conduction implantation...
Epidemiological Characteristics of COVID-19 Outbreak at Fitness Centers in Cheonan, Korea

Bae S, Kim H, Jung TY, Lim JA, Jo DH, Kang GS, Jeong SH, Choi DK, Kim HJ, Cheon YH, Chun Mk, Kim M, Choi S, Chun C, Shin SH, Kim HK, Park YJ, Park O, Kwon HJ

Background: In February 2020, a coronavirus disease 2019 (COVID-19) outbreak was reported in fitness centers in Cheonan, Korea. Methods: From February 24 to March 13, an epidemiological investigation was conducted on...
Analysis of the Change in Seropositive Rate of the Epstein-Barr Virus in Koreans: A Single-Center Study

Kim SK, Choi JS, Kim D, Kang CI, Chung DR, Peck KR, Kang ES, Kim YJ

Purpose: Epstein-Barr virus (EBV) infection is related to infectious mononucleosis or nasopharyngeal cancer, and its epidemiology may change according to the socioeconomic development of communities. This study aimed to evaluate...
Supervised Physical Rehabilitation in the Treatment of Patients with Advanced Cancer: a Systematic Review and Meta-analysis

Yang J, Choi M, Choi J, Kang M, Jo A, Chung SH, Sim SH, Kim YJ, Yang EJ, Yu SY

Background: As the survival rate of cancer patients increases, the clinical importance of rehabilitation provided by healthcare professionals also increases. However, the evidence supporting the relevance of rehabilitation programs is...
A novel urinary mRNA signature using the droplet digital polymerase chain reaction platform improves discrimination between prostate cancer and benign prostatic hyperplasia within the prostate-specific antigen gray zone

Kang HW, Lee HY, Byun YJ, Jeong P, Yoon JS, Kim DH, Kim WT, Kim YJ, Lee SC, Yun SJ, Kim WJ

Purpose: The aim of this study was to identify a noninvasive urinary marker for prostate cancer (PCa) diagnosis and to validate the clinical performance of this novel urinary mRNA signature...
Alterations in Structural and Functional Connectivities in Patients with End-Stage Renal Disease

Park BS, Kim SE, Lee HJ, Kim YW, Kim IH, Park JH, Park SH, Lee YJ, Seo SA, Park KM

Background and Purpose: The aim of this study was to evaluate the structural and functional connectivities of brain network using graph theoretical analysis in neurologically asymptomatic patients with end-stage renal...
Tuberculosis Surveillance and Monitoring under the National Public-Private Mix Tuberculosis Control Project in South Korea 2016–2017

Min J, Kim HW, Ko Y, Oh JY, Kang JY, Lee J, Park YJ, Lee SS, Park JS, Kim JS

Background: The national Public-Private Mix (PPM) tuberculosis (TB) control project provides for the comprehensive management of TB patients at private hospitals in South Korea. Surveillance and monitoring of TB under...
Refining General Principles of Antiepileptic Drug Treatments for Epilepsy

Kim KT, Kim DW, Yang KI, Lee ST, Byun JI, Seo JG, No YJ, Kang KW, Kim D, Cho YW, on behalf of the Drug Committee of Korean Epilepsy Society

Antiepileptic drugs (AEDs) are the primary treatment strategy for epilepsy. As the use of AEDs has become more widespread and diverse over the past century, it has become necessary to...
Effect of Cell Labeling on the Function of Human Pluripotent Stem Cell-Derived Cardiomyocytes

Choi SW, Cho YW, Kim JG, Kim YJ, Kim E, Chung HM, Kang SW

Cell labeling technologies are required to monitor the fate of transplanted cells in vivo and to select target cells for the observation of certain changes in vitro. Human induced pluripotent...
Comparing the Characteristics and Outcomes of Male and Female Breast Cancer Patients in Korea: Korea Central Cancer Registry

Lee EG, Jung SY, Lim MC, Lim J, Kang HS, Lee S, Han JH, Jo H, Won YJ, Lee ES

Purpose This study aimed to determine the incidence of male breast cancer (MBC) and its survival outcomes in Korea, and to compare these results to those for female breast cancer (FBC). Materials...
Clinical study of colorectal cancer operation: Survival analysis

Hong Y, Kim J, Choi YJ, Kang JG

Purpose: Overall 5-year survival rates for colon and rectal cancer reported recently by the American Cancer Society were 89%, 90% for localized disease, 71%, 71% for regional disease, and 14%,...
Usefulness and Complications of Needle Knife Fistulotomy as a Rescue Procedure in Patients with Pancreaticobiliary Disease

Lee YJ, Kang DH, Kim HW, Park SB, Kim SJ, Nam HS, Ryu DG

Background/Aims: Needle knife fistulotomy (NKF) is a technique to facilitate pancreatic and biliary duct access during ERCP. The double-guidewire technique (DGT) is also used in cases of difficult cannulation, but...
Validation of nutrient intake of smartphone application through comparison of photographs before and after meals

Lee H, Kim E, Kim SH, Lim H, Park YM, Kang JH, Kim H, Kim J, Park WY, Park S, Kim J, Yang YJ

Purpose: This study was conducted to evaluate the validity of the Gene-Health application in terms of estimating energy and macronutrients. Methods: The subjects were 98 health adults participating in a weight-control...
The Assessment of Bacterial and Fungal Biodiversity in Korean Dermatomycoses Patients: A Pilot Study

Chung BY, Seo JM, Kang MJ, Lee M, Shin J, Chung YJ, Yu DS, Lee YB

Background: Dermatophytes are the most common cause of fungal infections worldwide, having an estimated prevalence of 20% by the World Health Organization. Recent advances of sequencing and annotation of fungi...
Bone remodeling after conservative treatment of nasal bone fracture in pediatric patients

Kang WK, Han DG, Kim SE, Lee YJ, Shim JS

Background: The standard treatment of nasal bone fractures in pediatric patients is closed reduction. Conservative treatment is sometimes performed, but poses a risk of nasal deformity. The aim of this...

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