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BF-7 Improved Memory Function and Protected Neuron from Oxidative Stress

Lee M, Lee S, Lee J, Min K, Lee K, Yeo J, Kwon H, Lee J, Kang Y, Lee D, Chung Y, Kim K, Kim S, Lee W

Erratum: Perceptions, Attitudes, Behaviors, and Barriers to Effective Obesity Care in South Korea: Results from the ACTION-IO Study

Lim S, Oh B, Lee SH, Kim YH, Ha Y, Kang JH

Inhibition of cell growth and induction of apoptosis by acacetin in FaDu human pharyngeal carcinoma cells

Kang KR, Kim JS, Kim TH, Seo JY, Park JH, Lim JW, Yu SK, Kim HJ, Shin SH, Park BR, Kim CS, Kim DK

Acacetin, which is present in damiana (Turnera diffusa) and black locust (Robinia pseudoacacia), has several pharmacologic activities such as antioxidant, anti-inflammatory, and anti-proliferative effects on cancer cells. However, the effect...
Serrated Polyposis Syndrome with a Synchronous Colon Adenocarcinoma Treated by an Endoscopic Mucosal Resection

Lee SH, Lee SJ, Park SC, Nam SJ, Kang MH, Kim TS, Lee SK

Serrated polyposis syndrome (SPS) can transform to malignant lesions through the sessile serrated pathway and traditional serrated pathway. These pathways may cause rapid neoplastic progression compared to the adenoma-carcinoma sequence,...
Surgical strategy for patients with supratentorial spontaneous intracerebral hemorrhage: minimally invasive surgery and conventional surgery

Jang JH, Cho WS, Hong N, Pang CH, Lee SH, Kang HS, Kim JE

Objective: The role of surgery in spontaneous intracerebral hemorrhage (sICH) is still controversial. We aimed to investigate the effectiveness of minimally invasive surgery (MIS) compared to conventional surgery (CS) for...
Evaluation of the clinical efficacy of a TW3-based fully automated bone age assessment system using deep neural networks

Shin NY, Lee BD, Kang JH, Kim HR, Oh DH, Lee BI, Kim SH, Lee MS, Heo MS

Purpose: The aim of this study was to evaluate the clinical efficacy of a Tanner-Whitehouse 3 (TW3)-based fully automated bone age assessment system on hand-wrist radiographs of Korean children and...
The Usefulness of a 180° Rotatable Monitor for an Assistant to Overcome the Hand-Eye Discordance in Laparoscopic Colorectal Surgery

Kim S, Kang SI, Kim SH, Kim JH

Purpose: Hand-eye discordance during laparoscopic colon surgery is an obstacle to the assistant. We evaluated the usefulness of a 180° rotatable laparoscopic monitor for the colorectal surgery assistant to overcome...
Clinical Practice Guideline for Care in the Last Days of Life

Shin J, Chang YJ, Park SJ, Choi JY, Kim SH, Choi YS, Kim NH, Yum HK, Nam EM, Park MH, Moon N, Moon JY, Kang HT, Kang JH, Park JM, Lee CW, Kim SY, Lee EJ, Koh SJ, Kim Y, Agnes Cho M, Song Y, Shim JY

A clinical practice guideline for patients in the dying process in general wards and their families, developed through an evidence-based process, is presented herein. The purpose of this guideline is...
Intracranial Metaplastic Meningioma : Clinical and Radiological Characteristics of 11 Cases

Kim T, Kim JW, Ji SY, Kang H, Kim KM, Kim YH, Park CK, Choi SH, Park SH

Objective : Metaplastic meningioma is an extremely rare subtype of World Health Organization (WHO) grade I meningioma. It has distinctive histological subtypes according to its own mesenchymal components. Owing to...
Delphinidin enhances radio-therapeutic effects via autophagyinduction and JNK/MAPK pathway activation in non-small celllung cancer

Kang SH, Bak DH, Chung BY, Bai HW, Kang BS

Delphinidin is a major anthocyanidin compound found in various vegetablesand fruits. It has anti-oxidant, anti-inflammatory, and various other biologicalactivities. In this study we demonstrated the anti-cancer activity of delphinidin,which was...
Hourly wages of physicians within medical fees based on the Korean relative value unit system

Kim HA, Jung SH, Park IY, Kang SH

Background/Aims: It is difficult to reach a social agreement on the appropriate level of compensation for professionals. This study was performed to examine the physician fee embedded in the relative value unit...
Concomitant Use of NSAIDs or SSRIs with NOACs Requires Monitoring for Bleeding

Lee MT, Park KY, Kim MS, You SH, Kang YJ, Jung SY

Purpose: Non-vitamin K antagonist oral anticoagulants (NOACs) are widely used in patients with atrial fibrillation (AF) because of their effectiveness in preventing stroke and their better safety, compared with warfarin....
Beneficial Effect of Chloroquine and Amodiaquine on Type 1 Diabetic Tubulopathy by Attenuating Mitochondrial Nox4 and Endoplasmic Reticulum Stress

Kang JM, Lee HS, Kim J, Yang DH, Jeong HY, Lee YH, Kim DJ, Park SH, Sung M, Kim J, An HJ, Lee SH, Lee SY

Background: Oxidative stress induced by chronic hyperglycemia is recognized as a significant mechanistic contributor to the development of diabetic kidney disease (DKD). Nonphagocytic nicotinamide adenine dinucleotide phosphate oxidase 4 (Nox4) is...
Prognosis of Split Liver Transplantation Compared with Whole Liver Transplantation in Adult Patients: Single-center Results under the Korean MELD Score-based Allocation Policy

Park GC, Hwang S, Song GW, Jung DH, Ha TY, Ahn CS, Moon DB, Kim KH, Yoon YI, Kang WH, Cho HD, Choi JU, Kim M, Na BG, Kim SH, Lee SG

Background: Split liver transplantation (SLT) has been occasionally performed in Korea. This study compared the incidence and prognosis of SLT with whole liver transplantation (WLT) in adult patients. Methods: Between June...
Differential Diagnosis and Treatment Outcomes of Tumors at the Carotid Bifurcation

Kang J, Heo SH, Park YJ, Kim DI, Kim YW

Purpose: Primary tumor at the carotid bifurcation is uncommon, which includes paraganglioma, schwannoma, and lymphoma. Due to their rarity, characteristics of these tumors and problems related to their surgical treatment...
Characterization of changes in global gene expression in the hearts and kidneys of transgenic mice overexpressing human angiotensin-converting enzyme 2

Lee SH, Jee SW, Hwang DY, Kang JK

Human angiotensin-converting enzyme 2 (hACE2) has recently received a great attention due to it play a critical role as SARS-CoV receptor in the infection of human body. However, no further...
Diffuse Sclerosing Variant of Papillary Thyroid Carcinoma in a Child: A Case Report

Byun SH, You SK, Kang SS, Shin KS, Lee JE

The diffuse sclerosing variant of papillary thyroid carcinoma (DSPTC) is uncommon. Herein, we report a rare case of DSPTC in a 9-year-old girl who initially presented with a painless diffuse...
The platelet-to-lymphocyte ratio as a significant prognostic factor to predict survival outcomes in patients with synchronous metastatic renal cell carcinoma

Yuk HD, Kang M, Hwang EC, Park JY, Jeong CW, Song C, Seo SI, Byun SS, Kwak C, Hong SH, Chung J, Lee H

Purpose: The clinical impact of the platelet-to-lymphocyte ratio (PLR) on the prognosis of patients with metastatic renal cell carcinoma (mRCC) remains controversial. We investigated the associations between elevation of the...
Diallyl Biphenyl-Type Neolignans Have a Pharmacophore of PPARα/γ Dual Modulators

Han Y, Liu J, Ahn S, An S, Ko H, Shin JC, Jin SH, Ki MW, Lee SH, Lee KH, Shin SS, Choi WJ, Noh M

Adiponectin secretion-promoting compounds have therapeutic potentials in human metabolic diseases. Diallyl biphenyl-type neolignan compounds, magnolol, honokiol, and 4-O-methylhonokiol, from a Magnolia officinalis extract were screened as adiponectin-secretion promoting compounds in...
Repurposing Auranofin, an Anti-Rheumatic Gold Compound, to Treat Acne Vulgaris by Targeting the NLRP3 Inflammasome

Yang G, Lee SJ, Kang HC, Cho YY, Lee HS, Zouboulis CC, Han SH, Ma KH, Jang JK, Lee JY

Activation of the NLRP3 inflammasome is critical for host defense as well as the progression of inflammatory diseases through the production of the proinflammatory cytokine IL-1β, which is cleaved by...

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