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Evaluation of the clinical efficacy of a TW3-based fully automated bone age assessment system using deep neural networks

Shin NY, Lee BD, Kang JH, Kim HR, Oh DH, Lee BI, Kim SH, Lee MS, Heo MS

Purpose: The aim of this study was to evaluate the clinical efficacy of a Tanner-Whitehouse 3 (TW3)-based fully automated bone age assessment system on hand-wrist radiographs of Korean children and...
Influence of three BALB/c substrain backgrounds on the skin tumor induction efficacy to DMBA and TPA cotreatment

Kang MJ, Gong JE, Kim JE, Choi HJ, Bae SJ, Seo MS, Kim KS, Jung YS, Cho JY, Lim Y, Hwang DY

Differences in responsiveness of BALB/c substrains have been investigated in various fields, including diabetes induction, corpus callosum deficiency, virus-induced demyelinating disease, aggressive behavior and osteonecrosis. However, induction efficacy of skin...
Association between Relative Handgrip Strength and C-Reactive Protein in Adults

Park DY, Kang MS, Park JY, Kim MK, Choi BY, Kim YS

Purpose: The purpose of this study was to investigate whether obesity indicators are mediated in the association between muscle strength and inflammation levels, and further confirm the association between muscle...
Concomitant Use of NSAIDs or SSRIs with NOACs Requires Monitoring for Bleeding

Lee MT, Park KY, Kim MS, You SH, Kang YJ, Jung SY

Purpose: Non-vitamin K antagonist oral anticoagulants (NOACs) are widely used in patients with atrial fibrillation (AF) because of their effectiveness in preventing stroke and their better safety, compared with warfarin....
Changes of fat-mass and obesity-associated protein expression in the hippocampus in animal models of high-fat diet-induced obesity and D-galactose-induced aging

Kang MS, Kim TH, Choi JH, Kim W, Jung HY, Hwang IK, Kim W, Kwon HJ, Kim DW

Fat-mass and obesity-associated protein (Fto) is highly expressed in the brain including, the hippocampus, and its expression is significantly decreased in the brain of Alzheimer’s disease patients. In the present...
Prevalence of Toxocariasis and Its Risk Factors in Patients with Eosinophilia in Korea

Song HB, Lee D, Jin Y, Kang J, Cho SH, Park MS, Park JH, Song WJ, Kang HR, Lee SH, Hong ST, Choi MH

Eosinophilia occurs commonly in many diseases including allergic diseases and helminthic infections. Toxocariasis has been suggested as one cause of eosinophilia. The present study was undertaken to examine the prevalence...
Beta-blocker Therapy at Discharge in Patients with Acute Heart Failure and Atrial Fibrillation

Ahn MS, Yoo BS, Son JW, Yu MH, Kang DR, Lee HY, Jeon ES, Kim JJ, Chae SC, Baek SH, Kang SM, Choi DJ, Kim KH, Cho MC, Kim SY

Background: β-blockers (BBs) are considered primary therapy in stable heart failure (HF) with reduced ejection fraction (HFrEF) without atrial fibrillation (AF); evidence-based benefits of BB on outcome have been documented....
Surgical treatment of rhinophyma using an ordinary bur

Kang JK, Lee JS, Choi JH, Shin MS, Yun BM

Rhinophyma is a painless benign tumor of the skin of the nose. It is the most severe form of rosacea. Rhinophyma is particularly rare among Asians. It can be treated...
Clinical Characteristics of COVID-19: Clinical Dynamics of Mild Severe Acute Respiratory Syndrome Coronavirus 2 Infection Detected by Early Active Surveillance

Suh HJ, Kim DH, Heo EY, Lee HW, Lee JK, Lee CS, Kim M, Jeon YD, Chung JW, Kim YK, Shin PJ, Lee MS, Kang JS, Lee MJ, Kim BN, Park SW

Background: There is limited information describing the presenting characteristics and dynamic clinical changes in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection diagnosed in the early phase of illness. This...
Evaluation of changes in anesthetic methods for cesarean delivery: an analysis for 5 years using the big data of the Korean Health Insurance Review and Assessment Service

Park JI, Park SH, Kang MS, Kang GW, Kim ST

Background: As an anesthesia induced during cesarean section, spinal anesthesia is preferred over general and epidural anesthesia. This study aimed to review the trend of anesthetic methods for cesarean section...
Ischemic Colitis due to Fibromuscular Dysplasia Limited to the Inferior Mesenteric Artery: A Case Report

Park JH, Kwon HJ, Chang KS, Kang KA, Kim MS

Fibromuscular dysplasia is a nonatheromatous, noninflammatory arterial disorder that results in stenosis and/or aneurysm formation and rarely involves the mesenteric arteries. Herein, we report a case of fibromuscular dysplasia limited...
Comparison of the presentation of atopic dermatitis induced by trinitrochlorobenzene and house dust mite in NC/Nga mice

Kim YH, Kim TH, Kang MS, Ahn JO, Choi JH, Chung JY

Background: Atopic dermatitis (AD) is a common chronic inflammatory skin disease. To understand AD, there have been many trials establishing AD animal models. Although various trials to establish AD animal...
Selecting coronavirus disease 2019 patients with negligible risk of progression: early experience from non-hospital isolation facility in Korea

Choe PG, Kang EK, Lee SY, Oh B, Im D, Lee HY, Jung H, Kang CK, Kim MS, Park WB, Choi EH, Cho B, Oh Md, Kim NJ

Background/Aims: As the novel coronavirus (coronavirus disease 2019 [COVID-19]) outbreak progresses rapidly, staying home is recommended for suspected patients; however, the safety of this recommendation is uncertain. In Korea, non-hospital...
A Correlation between Serum Level of Alkaline Phosphatase and Acne Severity in Children and Adolescents: A Retrospective Cross-Sectional Study

Jue MS, Park E, Kang HS, Kim JS

Background: Acne is a chronic inflammatory disease of the pilosebaceous unit and usually affects adolescents when the peak concentrations of growth hormone, insulin-like growth factor 1, and androgen are demonstrated....
Impact of Diabetes Control on Subclinical Atherosclerosis: Analysis from Coronary Computed Tomographic Angiography Registry

Park GM, Lee CH, Lee SW, Yun SC, Kim YH, Kim YG, Won KB, Ann SH, Kim SJ, Yang DH, Kang JW, Lim TH, Koh EH, Lee WJ, Kim MS, Park JY, Kim HK, Choe J, Lee SG

Background: There are limited data on the impact of diabetes control on the risk of subclinical coronary atherosclerosis. Methods: We analyzed 6,434 consecutive asymptomatic individuals without previous history of coronary artery...
Predictors and outcomes of sepsis-induced cardiomyopathy in critically ill patients

Song MJ, Lee SH, Leem AY, Kim SY, Chung KS, Kim EY, Jung JY, Kang YA, Kim YS, Chang J, Park MS

Background: Sepsis-induced cardiomyopathy (SIC) occurs frequently in critically ill patients, but the clinical features and prognostic impact of SIC on sepsis outcome remain controversial. Here, we investigated the predictors and...
Two Cases of Cortical Blindness from Both Posterior Cerebral Artery Occlusion Following General Anesthesia Surgery

Kang MS, Kim SJ

Purpose: To report two rare cases of cortical blindness resulting from posterior cerebral artery (PCA) occlusion after laminectomy and laparoscopic gastrectomy under general anesthesia. Case summary: (Case 1) A 65-year-old man...
Two Cases of Oculopharyngeal Muscular Dystrophy in Brothers with Ptosis and Eye Movement Disorder

Bang S, Nam S, Lee JS, Park SH, Kang MS, Kim TG, Jin KH

Purpose: To report two cases of early onset oculopharyngeal muscular dystrophy, which were suspected to be chronic progressive external ophthalmoplegia. Case summary: Case 1, a 15-year-old male and Case 2, a...
A Prospective Observation of Psychological Distress in Patients With Anaphylaxis

Lee Y, Chang HY, Kim SH, Yang MS, Koh YI, Kang HR, Choi JH, Kim CW, Park HK, Kim JH, Nam YH, Kim TB, Hur GY, Jung JW, Park KH, Kim MA, Kim J, Yoon J, Ye YM

PURPOSE: Anaphylaxis is an immediate allergic reaction characterized by potentially life-threatening, severe, systemic manifestations. While studies have evaluated links between serious illness and posttraumatic stress disorder (PTSD), few have investigated...
Evaluation of Drug-Induced Liver Injury Developed During Hospitalization Using Electronic Health Record (EHR)-Based Algorithm

Kang Y, Kim SH, Park SY, Park BY, Lee JH, An J, Won HK, Song WJ, Kwon HS, Cho YS, Moon HB, Shim JH, Yang MS, Kim TB

PURPOSE: The incidence of drug-induced liver injury (DILI) has been increasing; however, few algorithms are available to identify DILI in electronic health records (EHRs). We aimed to identify and evaluate...

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