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The role of platelet function analyzer-200 in predicting perioperative bleeding risk

Yu ES, Jeon MJ, Kang KW, Lee BH, Kang EJ, Park Y, Lee SR, Sung HJ, Choi CW, Kim BS, Kim DS

  • Korean J Intern Med.
  • 2020 Sep;35(5):1199-1209.
  • doi: 10.3904/kjim.2019.112
Background/Aims: Various preoperative screening tests, such as platelet count, prothrombin time, activated partial thromboplastin time, and bleeding time, have been widely used to evaluate the risk of bleeding during surgery....
Recovery of Tenofovir-induced Nephrotoxicity following Switch from Tenofovir Disoproxil Fumarate to Tenofovir Alafenamide in Human Immunodeficiency Virus-Positive Patients

Seo JW, Kim K, Jun KI, Kang CK, Moon SM, Song KH, Bang JH, Kim ES, Kim HB, Park SW, Kim NJ, Choe PG, Park WB, Oh Md

  • Infect Chemother.
  • 2020 Sep;52(3):381-388.
  • doi: 10.3947/ic.2020.52.3.381
Background: Tenofovir disoproxil fumarate (TDF)-induced nephrotoxicity is related to high plasma tenofovir concentrations. Tenofovir alafenamide (TAF) is a tenofovir prodrug with 90% lower plasma tenofovir concentrations. The aim of this...
Pre-Transplant Angiotensin II Type 1 Receptor Antibodies and Anti-Endothelial Cell Antibodies Predict Graft Function and Allograft Rejection in a Low-Risk Kidney Transplantation Setting

Yu S, Huh HJ, Lee KW, Park JB, Kim SJ, Huh W, Jang HR, Kwon GY, Moon HH, Kang ES

  • Ann Lab Med.
  • 2020 Sep;40(5):398-408.
  • doi: 10.3343/alm.2020.40.5.398
Background: Non-HLA antibodies, anti-angiotensin II type 1 receptor antibodies (anti-AT1R) and anti-endothelial cell antibodies (AECA), are known to play a role in allograft rejection. We evaluated the role of both...
Hematopoietic Stem Cell Registry Report: 2018

Kang ES, Lim CS, Han KS, Kim DW

  • Korean J Blood Transfus.
  • 2020 Aug;31(2):109-118.
  • doi: 10.17945/kjbt.2020.31.2.109
Background: Hematopoietic stem cell (HSC) transplantation is an important therapeutic option for many malignant and non-malignant diseases. The whole transplant process involves multiple areas and complex steps. The laboratory procedures...
Epidemiological Study of Hereditary Hemolytic Anemia in the Korean Pediatric Population during 1997–2016: a Nationwide Retrospective Cohort Study

Shim YJ, Jung HL, Shin HY, Kang HJ, Choi JY, Hah JO, Lee JM, Lim YT, Yang EJ, Baek HJ, Choi HS, Yoo KH, Park JE, Kim S, Kim JY, Park ES, Im HJ, Chueh HW, Kim SK, Lee JH, Yoo ES, Park HJ, Lee JA, Park M, Kang HS, Park JK, Lee NH, Park SK, Lee YH, Lee SW, Choi EJ, Kong SG

  • J Korean Med Sci.
  • 2020 Aug;35(33):e279.
  • doi: 10.3346/jkms.2020.35.e279
Background: Hereditary hemolytic anemia (HHA) is a rare disease characterized by premature red blood cell (RBC) destruction due to intrinsic RBC defects. The RBC Disorder Working Party of the Korean...
Beta-blocker Therapy at Discharge in Patients with Acute Heart Failure and Atrial Fibrillation

Ahn MS, Yoo BS, Son JW, Yu MH, Kang DR, Lee HY, Jeon ES, Kim JJ, Chae SC, Baek SH, Kang SM, Choi DJ, Kim KH, Cho MC, Kim SY

  • J Korean Med Sci.
  • 2020 Aug;35(33):e278.
  • doi: 10.3346/jkms.2020.35.e278
Background: β-blockers (BBs) are considered primary therapy in stable heart failure (HF) with reduced ejection fraction (HFrEF) without atrial fibrillation (AF); evidence-based benefits of BB on outcome have been documented....
Analysis of the Change in Seropositive Rate of the Epstein-Barr Virus in Koreans: A Single-Center Study

Kim SK, Choi JS, Kim D, Kang CI, Chung DR, Peck KR, Kang ES, Kim YJ

  • Pediatr Infect Vaccine.
  • 2020 Aug;27(2):117-126.
  • doi: 10.14776/piv.2020.27.e18
Purpose: Epstein-Barr virus (EBV) infection is related to infectious mononucleosis or nasopharyngeal cancer, and its epidemiology may change according to the socioeconomic development of communities. This study aimed to evaluate...
Abdominal Digital Radiography with a Novel Post-Processing Technique: Phantom and Patient Studies

Kang H, Lee ES, Park HJ, Park BK, Park JY, Suh SW

  • J Korean Soc Radiol.
  • 2020 Jul;81(4):920-932.
  • doi: 10.3348/jksr.2020.81.4.920
Purpose The aim of this study was to evaluate the diagnostic image quality of low dose abdominal digital radiography processed with a new post-processing technique. Materials and Methods Abdominal radiographs from...
Vanillic Acid Stimulates Anagen Signaling via the PI3K/Akt/ β-Catenin Pathway in Dermal Papilla Cells

Kang JI, Choi YK, Koh YS, Hyun JW, Kang JH, Lee KS, Lee CM, Yoo ES, Kang HK

  • Biomol Ther.
  • 2020 Jul;28(4):354-360.
  • doi: 10.4062/biomolther.2019.206
The hair cycle (anagen, catagen, and telogen) is regulated by the interaction between mesenchymal cells and epithelial cells in the hair follicles. The proliferation of dermal papilla cells (DPCs), mesenchymal-derived...
Immature platelet fraction based diagnostic predictive scoring model for immune thrombocytopenia

Jeon MJ, Yu ES, Kang KW, Lee BH, Park Y, Lee SR, Sung HJ, Yoon SY, Choi CW, Kim BS, Kim DS

  • Korean J Intern Med.
  • 2020 Jul;35(4):970-978.
  • doi: 10.3904/kjim.2019.093
Background/Aims: The diagnosis of immune thrombocytopenia (ITP) is based on clinical manifestations and there is no gold standard. Thus, even hematologic malignancy is sometimes misdiagnosed as ITP and adequate treatment...
Comparing the Characteristics and Outcomes of Male and Female Breast Cancer Patients in Korea: Korea Central Cancer Registry

Lee EG, Jung SY, Lim MC, Lim J, Kang HS, Lee S, Han JH, Jo H, Won YJ, Lee ES

  • Cancer Res Treat.
  • 2020 Jul;52(3):739-746.
  • doi: 10.4143/crt.2019.639
Purpose This study aimed to determine the incidence of male breast cancer (MBC) and its survival outcomes in Korea, and to compare these results to those for female breast cancer (FBC). Materials...
Comparison of clinical outcomes between sentinel lymph node biopsy and axillary lymph node dissection in a single-center Z0011-eligible breast cancer cohort

Jo H, Lee EG, Song E, Han JH, Jung SY, Kang HS, Lee ES, Lee S

  • Korean J Clin Oncol.
  • 2020 Jun;16(1):18-24.
  • doi: 10.14216/kjco.20004
Purpose: The ACOSOG Z0011 trial has proven the oncological safety of sentinel lymph node biopsy (SLBx) for node negative breast cancer. Accordingly, treatment paradigm including axilla surgery was changed. We...
Prevalence and Risk Factors of Latent Tuberculosis Infection among Healthcare Workers Using Tuberculin Skin Test and Interferon-γ Release Assay at a Tertiary Hospital in South Korea

Kim SJ, Ha E, Park ES, Choi JY, Kang YA

  • Korean J Healthc Assoc Infect Control Prev.
  • 2020 Jun;25(1):46-53.
  • doi: 10.14192/kjicp.2020.25.1.46
Background: We evaluated the prevalence and risk factors associated with latent tuberculosis infections (LTBIs) among healthcare workers (HCWs) working in non-TB departments in a tertiary referral hospital. Methods: This study was...
Successful Sirolimus Treatment for Korean Patients with Activated Phosphoinositide 3-kinase δ Syndrome 1: the First Case Series in Korea

Kang JM, Kim SK, Kim D, Choi SR, Lim YJ, Kim SK, Park BK, Park WS, Kang ES, Ko YH, Choe YH, Lee JW, Kim YJ

  • Yonsei Med J.
  • 2020 Jun;61(6):542-546.
  • doi: 10.3349/ymj.2020.61.6.542
Activated phosphoinositide 3-kinase δ syndrome (APDS)1 is caused by gain-of-function mutations in PIK3CD, which encodes the catalytic p110δ subunit of phosphoinositide 3 kinase. We describe three patients with APDS1, the...
A scoring system for the diagnosis of non-alcoholic steatohepatitis from liver biopsy

Lee K, Jung ES, Yu E, Kang YK, Cho MY, Kim JM, Moon WS, Jeong JS, Park CK, Park JB, Kang DY, Sohn JH, Jin SY

  • J Pathol Transl Med.
  • 2020 May;54(3):228-236.
  • doi: 10.4132/jptm.2020.03.07
Background: Liver biopsy is the essential method to diagnose non-alcoholic steatohepatitis (NASH), but histological features of NASH are too subjective to achieve reproducible diagnoses in early stages of disease. We...
Association between Non-Alcoholic Steatohepatitis and Left Ventricular Diastolic Dysfunction in Type 2 Diabetes Mellitus

Lee H, Kim G, Choi YJ, Huh BW, Lee BW, Kang ES, Cha BS, Lee EJ, Lee Yh, Huh KB

  • Diabetes Metab J.
  • 2020 Apr;44(2):267-276.
  • doi: 10.4093/dmj.2019.0001
Background: Impaired diastolic heart function has been observed in persons with non-alcoholic fatty liver disease (NAFLD) and/or with type 2 diabetes mellitus (T2DM). However, it is unclear whether NAFLD fibrotic...
Treatment of Atypical Ulnar Fracture Associated with Bisphosphonate Therapy - A Case Report -

Kim DS, Park JK, Choi ES, Jeong HS, Hong SH, Ahn BH

  • J Korean Fract Soc.
  • 2020 Apr;33(2):101-104.
  • doi: 10.12671/jkfs.2020.33.2.101
Bisphosphonates can cause atypical fractures when taken for a long time. Atypical fractures appear mainly as femoral subtrochanteric or shaft fractures. On the other hand, reports of atypical fractures in...
Impact of Angiotensin Receptor Blockers, Beta Blockers,Calcium Channel Blockers and Thiazide Diuretics on Survivalof Ovarian Cancer Patients

Cho MA, Jeong SY, Sohn I, Kim MS, Kang JH, Paik ES, Lee YY, Choi CH

  • Cancer Res Treat.
  • 2020 Apr;52(2):645-654.
  • doi: 10.4143/crt.2019.509
Purpose We investigated the impact of four types of antihypertensive medications, angiotensin receptor blockers (ARBs), beta blockers (BBs; both selective and non-selective), calcium channel blockers (CCBs), and thiazide diuretics (TDs) on survival outcomes...
Pretreatment Lymph Node Metastasis as a Prognostic Significance inCervical Cancer: Comparison between Disease Status

Jeong SY, Park H, Kim MS, Kang JH, Paik ES, Lee YY, Kim TJ, Lee JW, Kim BG, Bae DS, Choi CH

  • Cancer Res Treat.
  • 2020 Apr;52(2):516-523.
  • doi: 10.4143/crt.2019.328
Purpose Lymph node metastasis (LNM) is the most significant prognostic factor in cervical cancer that was recently incorporated into the International Federation of Gynecology and Obstetrics (FIGO) staging system. This study was performed...
Impact of Multiple Prostate Biopsies: Risk of Perioperative Complications and Biochemical Recurrence After Radical Prostatectomy

Park KM, Chung JW, Kang JK, Shin TJ, Kwon SY, Jang HC, Ha YS, Choi SH, Jung W, Lee JN, Kim BH, Kim BS, Kim HT, Kim JS, Kim TH, Yoo ES, Lee KS, Kim CI, Chung SK, Kwon TG

  • Korean J Urol Oncol.
  • 2020 Apr;18(1):24-31.
  • doi: 10.22465/kjuo.2020.18.1.24
Purpose: The aim of this study was to analyze the perioperative complications and oncological outcomes of radical prostatectomy (RP) in patients who underwent multiple prostate biopsies. Materials and Methods: A total...

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