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Apolipoprotein B Levels Predict Future Development of Hypertension Independent of Visceral Adiposity and Insulin Sensitivity

Han SJ, Fujimoto WY, Kahn SE, Leonetti DL, Boyko EJ

Background: High plasma apolipoprotein B (apoB) levels have been shown to be associated with hypertension, central obesity, and insulin resistance in cross-sectional research. However, it is unclear whether apoB levels...
Intra-Abdominal Fat and High Density Lipoprotein Cholesterol Are Associated in a Non-Linear Pattern in Japanese-Americans

Song SO, Hwang YC, Kahn SE, Leonetti DL, Fujimoto WY, Boyko EJ

Background: We describe the association between high density lipoprotein cholesterol (HDL-C) concentration and computed tomography (CT)-measured fat depots. Methods: We examined the cross-sectional associations between HDL-C concentration and intra-abdominal (IAF), abdominal...
Higher High Density Lipoprotein 2 (HDL2) to Total HDL Cholesterol Ratio Is Associated with a Lower Risk for Incident Hypertension

Hwang YC, Fujimoto W, Kahn SE, Leonetti D, Boyko EJ

BACKGROUND: Recent studies have suggested that high density lipoprotein (HDL) cholesterol is inversely associated with the development of hypertension. We aimed to determine the association between different HDL cholesterol subclasses...
Predictors of Incident Type 2 Diabetes Mellitus in Japanese Americans with Normal Fasting Glucose Level

Hwang YC, Fujimoto W, Kahn SE, Leonetti D, Boyko EJ

BACKGROUND: Little is known about the natural course of normal fasting glucose (NFG) in Asians and the risk factors for future diabetes. METHODS: A total of 370 Japanese Americans (163 men,...
Association of Thigh Muscle Mass with Insulin Resistance and Incident Type 2 Diabetes Mellitus in Japanese Americans

Han SJ, Boyko EJ, Kim SK, Fujimoto W, Kahn SE, Leonetti D

BACKGROUND: Skeletal muscle plays a major role in glucose metabolism. We investigated the association between thigh muscle mass, insulin resistance, and incident type 2 diabetes mellitus (T2DM) risk. In addition,...
Translation: Roadmap for Harmonization of Clinical Laboratory Measurement Procedures

Miller WG, Myers GL, Gantzer ML, Kahn SE, Schonbrunner ER, Thienpont , Bunk DM, Christenson RH, Eckfeldt J, Lo SF, Nubling CM, Sturgeon C

Results between different clinical laboratory measurement procedures (CLMP) should be equivalent, within clinically meaningful limits, to enable optimal use of clinical guidelines for disease diagnosis and patient management. When laboratory...

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