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Microbleeds in the Corpus Callosum in Anoxic Brain Injury

Kim CS, Park DW, Kim TY, Lee YJ, Lee JY

Purpose: This study was performed to evaluate the relationship between callosal microbleeds and anoxic brain injury. Materials and Methods: Twenty-seven patients with anoxic brain injuries were analyzed and retrospectively compared to...
Prognostic Factors and Long-term Surgical Outcomes for Exudative Age-related Macular Degeneration with Breakthrough Vitreous Hemorrhage

Kim TY, Kang HG, Choi EY, Koh HJ, Kim SS, Lee JH, Kim M, Byeon SH, Lee CS

Purpose: We sought to evaluate the long-term outcomes for patients with exudative age-related macular degeneration (AMD) undergoing vitrectomy for breakthrough vitreous hemorrhage and to investigate possible prognostic factors. Methods: Consecutive patients...
Cholangitis Caused by Hereditary Spherocytosis in Adulthood Treated by Endoscopic Retrograde Cholangiopancreatography

Park TY, Jun JH, Kang H, Doh YS, Jang JW, Baek IH, Jung SH

Hereditary spherocytosis is a disease caused by deficiency of erythrocyte lipid membrane protein. Hereditary spherocytosis shows hemolysis of erythrocyte, and it leads to anemia, jaundice by elevation of indirect bilirubin....
Standardization of the Discrimination and Stigma Scale-Korean Version (DISC 12-K) in Patients with Depressive Disorders

Kim GO, Yoo TY, Kim NJ, Lee HJ, Jhon M, Kim JW, Kang HJ, Kim SW, Kim JM

Objective The Discrimination and Stigma Scale (DISC 12), which assesses behavioral and experienced stigma, has not been translated into Korean. We developed and standardized the Korean version of the DISC...
Effectiveness of nivolumab versus regorafenib in hepatocellular carcinoma patients who failed sorafenib treatment

Lee CH, Lee YB, Kim MA, Jang H, Oh H, Kim SW, Cho EJ, Lee KH, Lee JH, Yu SJ, Yoon JH, Kim TY, Kim YJ

Background/Aims: Several treatment options are currently available for patients with hepatocellular carcinoma (HCC) failing previous sorafenib treatment. We aimed to compare the effectiveness of regorafenib and nivolumab in these patients. Methods:...
G Protein–Coupled Receptor 30 Mediates the Anticancer Effects Induced by Eicosapentaenoic Acid in Ovarian Cancer Cells

Zhao Y, Zhao MF, Yang ML, Wu TY, Xu CJ, Wang JM, Li CJ, Li X

Purpose While numerous epidemiological studies have indicated that omega-3 polyunsaturated fatty acids have anticancer properties in various cancers, the effects and mechanisms of eicosapentaenoic acid (EPA) in ovarian cancer cell growth...
Effectiveness of Injecting Cold 5% Dextrose into Patients with Nerve Damage Symptoms during Thyroid Radiofrequency Ablation

Lee MK, Baek JH, Chung SR, Choi YJ, Lee YM, Kim TY, Lee JH

Background: Although radiofrequency ablation (RFA) is a safe treatment for thyroid tumors, nerve damage is a frequent complication. A previous retrospective study suggested that an injection of cold 5% dextrose...
ZNF804A Gene Variants Have a Cross-diagnostic Influence on Psychosis and Treatment Improvement in Mood Disorders

Calabrò M, Mandelli L, Crisafulli C, Nicola MD, Colombo R, Janiri L, Lee SJ, Jun TY, Wang SM, Masand PS, Patkar AA, Han C, Pae CU, Serretti A

Objective: Genetic variations in the gene encoding zinc finger protein 804A gene (ZNF804A) have been associated with major depression and bipolar disorder. In this work we focused on the potential...
Use of Paclitaxel Coated Drug Eluting Technology to Improve Central Vein Patency for Haemodialysis Access Circuits: Any Benefit?

Chong TT, Yap HY, Tan CS, Lee QS, Chan SL, Yan Wee IJ, Tang TY

Purpose: Central venous stenosis is a recurring problem affecting dialysis access patency. Increasing evidence suggests that the use of drug-coated balloons (DCBs) improves target lesion primary patency (TLPP) in dialysis...
Efficacy and Safety of Letibotulinum Toxin A for the Treatment of Essential Blepharospasm

Kim JH, Chung DH, Kim SE, Paik JS, Kim N, La TY, Son JH, Ahn HB, Yang JW, Woo KI, Lew H, Yoon JS, Lee SU, Lee SB, Lee JK, Jang JW, Choung HK, Chi M, Yang SW

PURPOSE: To evaluate the efficacy and safety of BOTULAX® in subjects with essential blepharospasm. METHODS: In this study, a total of 250 subjects with essential blepharospasm were enrolled at 15 investigational...
Computer-Aided Diagnosis System for the Evaluation of Thyroid Nodules on Ultrasonography: Prospective Non-Inferiority Study according to the Experience Level of Radiologists

Chung SR, Baek JH, Lee MK, Ahn Y, Choi YJ, Sung TY, Song DE, Kim TY, Lee JH

OBJECTIVE: To determine whether a computer-aided diagnosis (CAD) system for the evaluation of thyroid nodules is non-inferior to radiologists with different levels of experience. MATERIALS AND METHODS: Patients with thyroid nodules...
Functional Connectivity of the Striatum as a Neural Correlate of Symptom Severity in Patient with Obsessive-Compulsive Disorder

Park J, Kim T, Kim M, Lee TY, Kwon JS

Objective It is well established that the cortico-striato-thalamo-cortical (CSTC) circuit is implicated in the pathophysiology of obsessive- compulsive disorder (OCD). However, reports on corticostriatal functional connectivity (FC) in OCD have...
Sonographic Assessment of the Extent of Extrathyroidal Extension in Thyroid Cancer

Chung SR, Baek JH, Choi YJ, Sung TY, Song DE, Kim TY, Lee JH

Objective: This study aimed to determine the sonographic features suggestive of extrathyroidal extension (ETE) of thyroid cancers. Materials and Methods: We retrospectively reviewed the sonographic images of 1656 consecutive patients who...
Worsened survival in the head-up tilt position cardiopulmonary resuscitation in a porcine cardiac arrest model

Park YJ, Hong KJ, Shin SD, Kim TY, Ro YS, Song KJ, Ryu HH

OBJECTIVE: Head elevation at an angle of 30° during cardiopulmonary resuscitation (CPR) was hemodynamically beneficial compared to supine position in a previous porcine cardiac arrest experimental study. However, survival benefit...
Genes Involved in Neurodevelopment, Neuroplasticity and Major Depression: No Association for CACNA1C, CHRNA7 and MAPK1

Calabrò M, Mandelli L, Crisafulli C, Lee SJ, Jun TY, Wang SM, Patkar AA, Masand PS, Han C, Pae CU, Serretti A

OBJECTIVE: Genetics factors are likely to play a role in the risk, clinical presentation and treatment outcome in major depressive disorder (MDD). In this study, we investigated the role of...
Distribution and Characteristics of Meibomian Gland Dysfunction Subtypes: A Multicenter Study in South Korea

Eom Y, Na KS, Cho KJ, Hwang HS, Kim SW, Chung TY, Jun RM, Song JS, Kim HS, Korea Meibomian Gland & Ocular Surface Study Group

PURPOSE: We sought to evaluate the distribution and characteristics of meibomian gland dysfunction (MGD) and the treatment patterns for symptomatic MGD patients in South Korea. METHODS: One hundred ninety-six right eyes...
Effect of tDCS on Aberrant Functional Network Connectivity in Refractory Hallucinatory Schizophrenia: A Pilot Study

Yoon YB, Kim M, Lee J, Cho KI, Kwak S, Lee TY, Kwon JS

We aim to investigate the effect of fronto-temporal transcranial direct current stimulation (tDCS) on the interactions among functional networks and its association with psychotic symptoms. In this pilot study, we...
Validation of the Korean Version of the Prodromal Questionnaire-Brief Version in Non-Help-Seeking Individuals

Jang YE, Lee TY, Hur JW, Kwon JS

OBJECTIVE: In this study, we examined the reliability and validity of the Korean version of the Prodromal Questionnaire-Brief (PQ-B), a self-report screening instrument for clinical high risk for psychosis (CHR). METHODS:...
Usefulness of the Psoriatic Arthritis Screening and Evaluation Questionnaire to Monitor Disease Activity in Management of Patients with Psoriasis: Findings from the EPI-PSODE Study

Choe YB, Park CJ, Yu DY, Kim Y, Ju HJ, Youn SW, Lee JH, Kim BS, Seo SJ, Yun SK, Park J, Kim NI, Youn JI, Lee SJ, Lee MG, Kim KJ, Ro YS, Song HJ, Shin BS, Ahn SK, Lee JY, Won YH, Jang MS, Kim KH, Kim MH, Kim TY, Choi JH

BACKGROUND: Psoriasis and psoriatic arthritis (PsA) are included in the group of immune-mediated inflammatory diseases (IMIDs) caused by systemic inflammation; however, indicators for monitoring inflammatory activity in patients with psoriasis,...
Amenorrhea and Menopause in Patients with Breast Cancer after Chemotherapy

Shin JJ, Choi YM, Jun JK, Lee KH, Kim TY, Han W, Im SA

PURPOSE: The probability of ovarian failure after cytotoxic chemotherapy in patients with breast cancer has not been well established in Korea. This study aimed to assess the rate of ovarian...

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