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15-Deoxy-Δ12,14 -prostaglandin J2 Induces Epithelial-tomesenchymal Transition in Human Breast Cancer Cells and Promotes Fibroblast Activation

Choi 1 J, Suh JY, Kim DH, Na HK, Surh YJ

In inflammation-associated carcinogenesis, COX-2 is markedly overexpressed, resulting in accumulation of various prostaglandins. 15-deoxy-Δ 12,14 -prostaglandin J 2 (15d-PGJ2 ) is one of the terminal products of COX-2-catalyzed...
A Case of Diffuse Lichen Planus Pigmentosus on Exposed Areas Occurred with Lichen Planus

Kim SM, Kang JW, Kim WJ, Ro BI, Cho HK

  • KMID: 2506593
  • Korean J Dermatol.
  • 2020 Sep;58(8):566-568.
Clinical Guidelines for Drug-induced Peptic Ulcer, 2020 Revised Edition

Joo MK, Park CH, Kim JS, Park JM, Ahn JY, Lee BE, Lee JH, Yang HJ, Cho YK, Bang CS, Kim BJ, Jung HK, Kim BW, Lee YC, Korean College of Helicobacter and Upper Gastrointestinal Research

The Korean guidelines for nonsteroidal anti-inflammatory drug (NSAID)-induced peptic ulcers were previously developed under co-work with the Korean College of Helicobacter and Upper Gastrointestinal Research and Korean Society of Gastroenterology...
Clinical Practice Guideline for Care in the Last Days of Life

Shin J, Chang YJ, Park SJ, Choi JY, Kim SH, Choi YS, Kim NH, Yum HK, Nam EM, Park MH, Moon N, Moon JY, Kang HT, Kang JH, Park JM, Lee CW, Kim SY, Lee EJ, Koh SJ, Kim Y, Agnes Cho M, Song Y, Shim JY

A clinical practice guideline for patients in the dying process in general wards and their families, developed through an evidence-based process, is presented herein. The purpose of this guideline is...
Early Surgery versus Watchful Waiting in Patients with Moderate Aortic Stenosis and Left Ventricular Systolic Dysfunction

Moon I, Kim M, Choi JW, Park JB, Hwang HY, Kim HK, Kim YJ, Kim KH, Kim KB, Sohn DW, Lee SP

Background and Objectives: Severe aortic stenosis (AS) with left ventricular systolic dysfunction (LVSD) is a class I indication for aortic valve replacement (AVR) but this recommendation is not well established...
The clinical meaning of pre- and post-ablation thyroglobulin levels at first radioiodine therapy in patients with papillary thyroid cancer

Kim HK, Yoon JH, Cho JS, Kwon SY, Yoo SW, Kang HC

Background/Aims: This study was conducted to identify prognostic factors in patients with papillary thyroid cancer (PTC) at the time of first radioactive iodine (RAI) therapy, and to evaluate the clinical...
The health-related quality-of-life of chronic obstructive pulmonary disease patients and disease-related indirect burdens

Choi HS, Yang DW, Rhee CK, Yoon HK, Lee JH, Lim SY, Kim YI, Yoo KH, Hwang YI, Lee SH, Park YB

Background/Aims: Many chronic obstructive pulmonary disease (COPD) patients have physical limitations. We investigated EuroQol five-dimensions five-level (EQ-5D-5L) of COPD patients to assess quality of life, and assessed indirect burden including time...
Guidelines for Surgery of Confirmed or Suspected COVID-19 Patients

Lee JS, Yum HK, Si HJ, Han SH, Park SY, Peck KR, Eom JS, Korean Society of Infectious Diseases (KSID) and Korea Medical Association Task Force Expert Committee

Coronavirus disease 2019 (COVID-19) has spread widely across the world since January 2020. There are many challenges when caring for patients with COVID-19, one of which is infection prevention and control....
Lymphatic Vessels Mapping in the Lower Extremities of a Healthy Asian Population

Lee YH, Kim HK, You HJ, Kim DW

Purpose: Intraoperative indocyanine green (ICG) lymphography is an effective tool to obtain real-time video images of functioning lymph vessels in edematous limbs. However, it is difficult to identify the course...
A Universal Screening Strategy for SARS-CoV-2 Infection in Intensive Care Units: Korean Experience in a Single Hospital

Chang E, Choi JS, Park TY, Kim SBK, Ko S, Kwon YS, Kim EJ, Song H, Noh HK, Park SW

Background: Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection is not differentiated clinically from other respiratory infections, and intensive care units (ICUs) are vulnerable to in-hospital transmission due to interventions inducing respiratory...
A Case of Hereditary Hemorrhagic Telangiectasia

Ryu GW, Park HK, Lee JB, Kim SJ, Lee SC, Won YH, Yun SJ

  • KMID: 2505561
  • Korean J Dermatol.
  • 2020 Aug;58(7):476-479.
Hereditary hemorrhagic telangiectasia (HHT), also known as Osler–Weber–Rendu syndrome, is a rare autosomal dominant genetic disorder that results in vascular malformation in the skin, mucous membrane, and other internal organs,...
Risk Factors Related to Poor Threshold, Discrimination, and Identification Scores in Patients with Chronic Rhinosinusitis with Olfactory Dysfunction

Kang DW, Min HK, Kwon OE, Kim SW, Min JY

Background and Objectives Although patients with chronic rhinosinusitis (CRS) present a similar degree of olfactory dysfunction, their impairments in threshold, discrimination, and identification test results may vary. We investigated factors...
Diagnostic Usefulness of an Ultra-Brief Screener to Identify Risk of Online Gaming Disorder for Children and Adolescents

Jo SJ, Jeong H, Son HJ, Lee HK, Lee SY, Kweon YS, Yim HW

Objective This study examined the diagnostic validity of a three-item ultra-brief screening tool for online gaming disorder in line with the gaming disorder criteria in the International Classification of Diseases...
Epidemiological Characteristics of COVID-19 Outbreak at Fitness Centers in Cheonan, Korea

Bae S, Kim H, Jung TY, Lim JA, Jo DH, Kang GS, Jeong SH, Choi DK, Kim HJ, Cheon YH, Chun Mk, Kim M, Choi S, Chun C, Shin SH, Kim HK, Park YJ, Park O, Kwon HJ

Background: In February 2020, a coronavirus disease 2019 (COVID-19) outbreak was reported in fitness centers in Cheonan, Korea. Methods: From February 24 to March 13, an epidemiological investigation was conducted on...
Clinical Course and Outcomes of 3,060 Patients with Coronavirus Disease 2019 in Korea, January–May 2020

Sung HK, Kim JY, Heo J, Seo H, Jang Ys, Kim H, Koh BR, Jo N, Oh HS, Baek YM, Park KH, Shon JA, Kim MC, Kim JH, Chang HH, Park Y, Kang YM, Lee DH, Oh DH, Park HJ, Song KH, Lee EK, Jeong H, Lee JY, Ko JY, Choi J, Ryu EH, Chung Kh, Oh Md, The Korea National Committee for Clinical Management of COVID-19

Background: The fatality rate of patients with coronavirus disease 2019 (COVID-19) varies among countries owing to demographics, patient comorbidities, surge capacity of healthcare systems, and the quality of medical care....
KSNM/KSID/KOSHIC Guidance for Nuclear Medicine Department Against the Coronavirus Disease 2019 (COVID-19) Pandemic

Bang JI, Lee HY, Cho YS, Choi H, Chong A, Eo JS, Kim JY, Kim TS, Kwon HW, Lee EJ, Lee ES, Park HL, Park SB, Shim Hk, Song BI, Yoo ID, Lee KJ, Lee HJ, Han SH, Lee JS, Park JM, Kim SH

The dramatic spread of Coronavirus Disease 2019 (COVID-19) has profound impacts on every continent and life. Due to humanto-human transmission of COVID-19, nuclear medicine staffs also cannot escape the risk...
Application of Novel Intraoperative Neuromonitoring System Using an Endotracheal Tube With Pressure Sensor during Thyroid Surgery: A Porcine Model Study

Sung ES, Shin SC, Kwon HK, Kim J, Park DH, Choi SW, Kim SH, Lee JC, Ro JH, Lee BJ

Objectives. The loss of signal during intraoperative neuromonitoring (IONM) using electromyography (EMG) in thyroidectomy is one of the biggest problems. We have developed a novel IONM system with an endotracheal...
The KAAACI/KDA Evidence-Based Practice Guidelines for Chronic Spontaneous Urticaria in Korean Adults and Children: Part 1. Definition, Methodology and First-line Management

Song WJ, Choi M, Lee DH, Kwon JW, Kim GW, Kim MH, Kim MA, Kim MH, Kim BK, Kim S, Kim JS, Kim JE, Kim JY, Kim JH, Kim HJ, Kim HO, Kim HB, Roh JY, Park KH, Park KY, Park HK, Park H, Bae JM, Byun JY, Song DJ, Ahn YM, Lee SE, Lee YB, Lee JS, Lee JH, Lim KH, Ye YM, Chang YS, Jeon YH, Jeon J, Jue MS, Choi SH, Choi JH, Hur GY, Park YM, Lim DH, Youn SW

Chronic spontaneous urticaria (CSU) is defined as the occurrence of spontaneous wheals, angioedema, or both for >6 weeks in the absence of specific causes. It is a common condition associated...
Does the Use of a Silicone Ring Tourniquet Help Reduce Bleeding in the Minimally Invasive Internal Fixation with Locking Plate for Distal Femoral Fractures?

Park KB, Jin HK, Hwang IY, Chang SW, Na SC

Purpose: This study evaluated the usefulness of a silicone ring tourniquet by analyzing the changes in the perioperative hemoglobin (Hb) levels or amount of perioperative bleeding compared to those of...
Clinical Perspectives of Parkinson's Disease for Ophthalmologists, Otorhinolaryngologists, Cardiologists, Dentists, Gastroenterologists, Urologists, Physiatrists, and Psychiatrists

Choi JH, Kim JM, Yang HK, Lee HJ, Shin CM, Jeong SJ, Kim WS, Han JW, Yoon IY, Song YS, Bae YJ

Parkinson's disease (PD) is a multisystemic disorder characterized by various non-motor symptoms (NMS) in addition to motor dysfunction. NMS include sleep, ocular, olfactory, throat, cardiovascular, gastrointestinal, genitourinary, or musculoskeletal disorders....

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