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Anti-adipogenic Pregnane Steroid from a Hydractinia-associated Fungus, Cladosporium sphaerospermum SW67

Lee SR, Kang H, Yoo MJ, Yi SA, Beemelmanns C, Lee J, Kim KH

A pregnane steroid, 3α-hydroxy-pregn-7-ene-6,20-dione (1), was isolated from a Hydractinia-associated Cladosporium sphaerospermum SW67 by repetitive column chromatographic separation and highperformance liquid chromatography (HPLC) purification. The planar structure of 1 was...
Morin Hydrate Inhibits Influenza Virus entry into Host Cells and Has Anti-inflammatory Effect in Influenzainfected Mice

Hong EH, Song aH, Kim SR, Cho J, Jeong B, Yang H, Jeong JH, Ahn JH, Jeong H, Kim SE, Chang SY, Ko HJ

Influenza virus is the major cause of seasonal and pandemic flu. Currently, oseltamivir, a potent and selective inhibitor of neuraminidase of influenza A and B viruses, is the drug of...
Hydrogel Production Platform with Dynamic Movement UsingPhoto-Crosslinkable/Temperature Reversible Chitosan Polymerand Stereolithography 4D Printing Technology

Seo JW, Shin SR, Park YJ, Bae H

BACKGROUND: Three-dimensional (3D) printing using hydrogel has made great strides when it comes to mimicking 3Dartificial tissue in the medical field. However, most structures do not mimic the dynamic movement...
Effectiveness of Injecting Cold 5% Dextrose into Patients with Nerve Damage Symptoms during Thyroid Radiofrequency Ablation

Lee MK, Baek JH, Chung SR, Choi YJ, Lee YM, Kim TY, Lee JH

Background: Although radiofrequency ablation (RFA) is a safe treatment for thyroid tumors, nerve damage is a frequent complication. A previous retrospective study suggested that an injection of cold 5% dextrose...
Long-Term Results of Thermal Ablation of Benign Thyroid Nodules: A Systematic Review and Meta-Analysis

Cho SJ, Baek JH, Chung SR, Choi YJ, Lee JH

Background: Ultrasound-guided thermal ablations have become one of the main options for treating benign thyroid nodules. To determine efficacy of thermal ablation of benign thyroid nodules, we performed a meta-analysis...
Detection and Isolation of SARS-CoV-2 in Serum, Urine, and Stool Specimens of COVID-19 Patients from the Republic of Korea

Kim JM, Kim HM, Lee EJ, Jo HJ, Yoon Y, Lee NJ, Son J, Lee YJ, Kim MS, Lee YP, Chae SJ, Park KR, Cho SR, Park S, Kim SJ, Wang E, Woo S, Lim A, Park SJ, Jang J, Chung YS, Chin BS, Lee JS, Lim D, Han MG, Yoo CK

Objectives Coronavirus Disease-19 (COVID-19) is a respiratory infection characterized by the main symptoms of pneumonia and fever. It is caused by the novel coronavirus severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2), which...
Empathy, Awareness and Attitudes toward Violence among Elementary School Students

Kang SR, Cho H, Kim SJ

Purpose: The purpose of this study was to investigate empathy, awareness, and attitudes toward violence among elementary school students. Methods: The participants were 195 fifth and sixth grade students in...
Status of HPV vaccination among HPV-infected women aged 20–60 years with abnormal cervical cytology in South Korea: a multicenter, retrospective study

Seong J, Ryou S, Yoo M, Lee J, Kim K, Jee Y, Cho CH, Kim SM, Hong SR, Jeong DH, Lee WC, Park JS, Kim TJ, Kee MK

Objectives: Since 2007, human papillomavirus (HPV) vaccines have been administered for the prevention of cervical cancer in Korea. We investigated the status of HPV vaccination among HPV-infected adult women with...
Type III Usher Syndrome in the Republic of Korea

Kim JH, Bang SR, Jeong JG, Cho NC

Purpose: To report a case of type III Usher syndrome that has not been previously reported in the Republic of Korea. Case summary: A 39-year-old female visited the local eye clinic...
Three-dimensional dose reconstruction-based pretreatment dosimetric verification in volumetric modulated arc therapy for prostate cancer

Jeong Y, Oh JG, Kang JK, Moon SR, Lee KK

Purpose: We performed three-dimensional (3D) dose reconstruction-based pretreatment verification to evaluate gamma analysis acceptance criteria in volumetric modulated arc therapy (VMAT) for prostate cancer. Materials and Methods: Pretreatment verification for 28...
Current Status and Future Strategies to Treat Spinal Cord Injury with Adult Stem Cells

Jeong SK, Choi I, Jeon SR

Spinal cord injury (SCI) is one of the most devastating conditions and many SCI patients suffer neurological sequelae. Stem cell therapies are expected to be beneficial for many patients with...
Oral Spironolactone Treatment in Chronic Central Serous Chorioretinopathy

Chung SR, Jeong JG, Lee TE, You IC, Ahn M, Cho NC

PURPOSE: To evaluate the effect of oral spironolactone for non-resolving chronic central serous chorioretinopathy after intravitreal bevacizumab injection. METHODS: Seventeen eyes of 17 patients with non-resolving chronic central serous chorioretinopathy after...
Computer-Aided Diagnosis System for the Evaluation of Thyroid Nodules on Ultrasonography: Prospective Non-Inferiority Study according to the Experience Level of Radiologists

Chung SR, Baek JH, Lee MK, Ahn Y, Choi YJ, Sung TY, Song DE, Kim TY, Lee JH

OBJECTIVE: To determine whether a computer-aided diagnosis (CAD) system for the evaluation of thyroid nodules is non-inferior to radiologists with different levels of experience. MATERIALS AND METHODS: Patients with thyroid nodules...
Epithelial PI3K-δ Promotes House Dust Mite-Induced Allergic Asthma in NLRP3 Inflammasome-Dependent and -Independent Manners

Kim SR, Park HJ, Lee KB, Kim HJ, Jeong JS, Cho SH, Lee YC

PURPOSE: Phosphoinositide 3-kinase (PI3K)-δ-dependent Akt activation is known to play critical roles in various immune responses of white blood cells in which PI3K-δ isoform is mostly expressed in contrast to...
Efficacy and Safety of Omega-3 Fatty Acids in Patients Treated with Statins for Residual Hypertriglyceridemia: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Jun JE, Jeong IK, Yu JM, Kim SR, Lee IK, Han KA, Choi SH, Kim SK, Park HK, Mok JO, Lee YH, Kwon HS, Kim SH, Kang HC, Lee SA, Lee CB, Choi KM, Her SH, Shin WY, Shin MS, Ahn HS, Kang SH, Cho JM, Jo SH, Cha TJ, Kim SY, Won KH, Kim DB, Lee JH, Lee MK

BACKGROUND: Cardiovascular risk remains increased despite optimal low density lipoprotein cholesterol (LDL-C) level induced by intensive statin therapy. Therefore, recent guidelines recommend non-high density lipoprotein cholesterol (non-HDL-C) as a secondary...
Sonographic Assessment of the Extent of Extrathyroidal Extension in Thyroid Cancer

Chung SR, Baek JH, Choi YJ, Sung TY, Song DE, Kim TY, Lee JH

Objective: This study aimed to determine the sonographic features suggestive of extrathyroidal extension (ETE) of thyroid cancers. Materials and Methods: We retrospectively reviewed the sonographic images of 1656 consecutive patients who...
The Influence of Social Media Affinity on Eating Attitudes and Body Dissatisfaction in Philippine Adolescents

Tadena S, Kang SR, Kim SJ

Purpose: This study aimed to examine the influence of social media affinity on eating attitudes and body dissatisfaction among adolescents in the Philippines. Methods: The participants were 114 junior high school...
Relationship between health risk behaviors, oral health-related behaviors, and experiences of oral symptoms in Korean adolescents: based on 2018 Korea Youth Risk Behavior Web-based Survey

Jeong SR, Jang JE

OBJECTIVES: This study investigates the relationship between risky health behaviors, occurrence of oral symptoms, and oral health-related behaviors. METHODS: The subjects were 60,040 adolescents selected from the web-based survey from the...
Temporal Trends of Cardiac Implantable Electronic Device Implantations: a Nationwide Population-based Study

Lee JH, Lee SR, Choi EK, Jeong J, Park HD, You SJ, Lee SS, Oh S

BACKGROUND AND OBJECTIVES: Implantation of cardiac implantable electronic devices (CIED), including permanent pacemakers (PM), implantable cardioverter-defibrillators (ICD), and cardiac resynchronization therapy (CRT) devices, has increased significantly over the past several...
Reference values of hematological and biochemical parameters in young-adult cynomolgus monkey (Macaca fascicularis) and rhesus monkey (Macaca mulatta) anesthetized with ketamine hydrochloride

Koo BS, Lee DH, Kang P, Jeong KJ, Lee S, Kim K, Lee Y, Huh JW, Kim YH, Park SJ, Jin YB, Kim SU, Kim JS, Son Y, Lee SR

Nonhuman primate models are valuable in biomedical research. However, reference data for clinical pathology parameters in cynomolgus and rhesus monkeys are limited. In the present study, we established hematologic and...

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