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Factors Related to Failure of Conservative Treatment in Volar Plate Avulsion Fractures of the Proximal Interphalangeal Joint

Lee S, Jang SJ, Jeon SH

Background: Volar plate avulsion fractures of the proximal interphalangeal (PIP) joint are a common hand injury and have been treated conservatively with favorable results. We assumed that conservative treatment of...
Surgical strategy for patients with supratentorial spontaneous intracerebral hemorrhage: minimally invasive surgery and conventional surgery

Jang JH, Cho WS, Hong N, Pang CH, Lee SH, Kang HS, Kim JE

Objective: The role of surgery in spontaneous intracerebral hemorrhage (sICH) is still controversial. We aimed to investigate the effectiveness of minimally invasive surgery (MIS) compared to conventional surgery (CS) for...
Inhibitory actions of borneol on the substantia gelatinosa neurons of the trigeminal subnucleus caudalis in mice

Nguyen PTT, Jang SH, Rijal S, Park SJ, Han SK

The substantia gelatinosa (SG) of the trigeminal subnucleus caudalis(Vc) is the first relay site for the orofacial nociceptive inputs via the thin myelinatedAδ and unmyelinated C primary afferent fibers. Borneol,...
Prognostic Value of Coronary CT Angiography forPredicting Poor Cardiac Outcome in Stroke Patientswithout Known Cardiac Disease or Chest Pain:The Assessment of Coronary Artery Disease in StrokePatients Study

Yoon SH, Kim E, Jeon Y, Yi SY, Bae HJ, Jang IK, Lee JM, Yoo SM, White CS, Chun EJ

Objective: To assess the incremental prognostic value of coronary computed tomography angiography (CCTA) in comparison toa clinical risk model (Framingham risk score, FRS) and coronary artery calcium score (CACS) for...
Severity of foot process effacement is associated with proteinuria in patients with IgA nephropathy

Lee JH, Jang SH, Cho NJ, Heo NH, Gil HW, Lee EY, Moon JS, Park S

Background: Proteinuria is a significant risk factor for progression of IgA nephropathy (IgAN) and has a positive correlation with severity of foot process effacement (FPE). We evaluated the relationship of...
Epidemiologic Features of Distal Radius Fractures in Severe Trauma Patients at the Busan Regional Trauma Center

Kim DH, Kwak SH, Jang HS, An SJ, Lee GE, Cho YJ, Lee SH

Purpose: Distal radius fractures (DRFs) are often observed in simple trauma in older women with osteoporosis, and severe trauma caused by traffic or fall accidents. In this study, we aim...
Repurposing Auranofin, an Anti-Rheumatic Gold Compound, to Treat Acne Vulgaris by Targeting the NLRP3 Inflammasome

Yang G, Lee SJ, Kang HC, Cho YY, Lee HS, Zouboulis CC, Han SH, Ma KH, Jang JK, Lee JY

Activation of the NLRP3 inflammasome is critical for host defense as well as the progression of inflammatory diseases through the production of the proinflammatory cytokine IL-1β, which is cleaved by...
Management of Patients With Advanced Prostate Cancer: Establishment ofTreatment Guidelines Through Prostate Cancer Summit (PCAS) 2016Composed of Korean Prostate Cancer Experts

Jang CT, Kim HJ, Kim MK, Park SW, Park SC, Park JY, Lee DH, Lee SH, Jeon HG, Chung JH, Jeong H, Jo MK, Hong SH, Kwak C, Lee JY, Kwon DD, Kim CS, Jeon SS

Purpose: The Advanced Prostate Cancer Consensus Conference (APCCC) 2015 was based on topics withcontroversy in the field of advanced prostate cancer. To understand the Korean urologists perspective regardingthe issues, we...
Epigenetic Approaches to the Treatment of Renal Cell Cancer

Hong SH, Lee J, Jang EB, Park SY, Moon HS, Yoon YE

To summarize the epigenetics in renal cell carcinoma (RCC) and discuss the potential use of epigenetic modifiersas RCC biomarkers and treatments. Pertinent articles available on PubMed and google scholar database...
Reliability and Validity of the Korean Version of Somatic Symptom Scale-8

Yang CM, Hwang KS, Lee SY, Seo JS, Jang SH

Objective Somatic symptoms in psychiatry include underlying depression, anxiety, or other psychiatric disorders. This study aimed to conduct a validation study of a Korean version of the Somatic Symptom Scale-8...
Epidemiological Characteristics of COVID-19 Outbreak at Fitness Centers in Cheonan, Korea

Bae S, Kim H, Jung TY, Lim JA, Jo DH, Kang GS, Jeong SH, Choi DK, Kim HJ, Cheon YH, Chun Mk, Kim M, Choi S, Chun C, Shin SH, Kim HK, Park YJ, Park O, Kwon HJ

Background: In February 2020, a coronavirus disease 2019 (COVID-19) outbreak was reported in fitness centers in Cheonan, Korea. Methods: From February 24 to March 13, an epidemiological investigation was conducted on...
The First Case of an Infant with Familial A20 Haploinsufficiency in Korea

Kim HY, Song JY, Kim WI, Ko HC, Park SE, Jang JH, Kim SH

Haploinsufficiency of A20 (HA20) is a newly described autoinflammatory disease caused by loss-of-function mutations in the TNFAIP3 gene. Clinical phenotypes are heterogenous and resemble Behçet's disease, juvenile idiopathic arthritis, inflammatory...
Preliminary Clinical Trial of Balance Compensation System for Improvement of Balance in Patients With Spinocerebellar Ataxia

Hong JS, Kim JH, Yong SY, Lee YH, Kim SH, Park JY, Lee JK, Jang JY

Objective To determine the immediate and short-term impact of the application of wearable balance compensation system (BCS) on balance impairment in patients with spinocerebellar ataxia (SCA). Methods The study enrolled 6...
Comparison of Neuropathological Characteristics between Multiple System Atrophy Cerebellar Type and Parkinsonian Type

Kim EJ, Lee S, Jang SH, Lee MJ, Lee JH, Shin JH, Lee YM, Pak K, Jung NY, Yoon JA, Ko JK, Lee JM, Lee K, Hwang C, Ahn JW, Sung S, Choi KU, Huh GY

Background: Multiple system atrophy (MSA) is a sporadic neurodegenerative disease characterized by various combinations of parkinsonism, cerebellar ataxia, autonomic dysfunction and pyramidal signs. Two clinical subtypes are recognized: MSA with...
Network Analysis of Language Disorganization in Patients with Schizophrenia

Park SC, Kim K, Jang OJ, Yoon HJ, Jang SH, Kim SW, Lee BJ, Park JH, Lee KU, Choi J

Language disorganization, an objective component of formal thought process abnormality, has been regarded as a core symptom of schizophrenia from an evolutionary psychopathology perspective. However, to the best of our...
Cholangitis Caused by Hereditary Spherocytosis in Adulthood Treated by Endoscopic Retrograde Cholangiopancreatography

Park TY, Jun JH, Kang H, Doh YS, Jang JW, Baek IH, Jung SH

Hereditary spherocytosis is a disease caused by deficiency of erythrocyte lipid membrane protein. Hereditary spherocytosis shows hemolysis of erythrocyte, and it leads to anemia, jaundice by elevation of indirect bilirubin....
Impact of Grilling Meat or Fish at Home on Peak Expiratory Flow Rate in Adults With Asthma

Lee H, Chung SJ, Park JS, Kim S, Park DW, Sohn JW, Kim SH, Park CS, Yoon HJ

Grilling, a common cooking method worldwide, can produce more toxic gases than other cooking methods. However, the impact of frequently grilling meat or fish at home on airflow limitation in...
Activation of Transient Receptor Potential Melastatin Family Member 8 (TRPM8) Receptors Induces Proinflammatory Cytokine Expressions in Bronchial Epithelial Cells

Kim JH, Jang YS, Kim HI, Park JY, Park Sh, Hwang YI, Jang SH, Jung KS, Park HS, Park CS

Purpose: Cold air is a major environmental factor that exacerbates asthma. Transient receptor potential melastatin family member 8 (TRPM8) is a cold-sensing channel expressed in the airway epithelium. However, its...
Altered Mitochondrial Functions and Morphologies in Epithelial Cells Are Associated With Pathogenesis of Chronic Rhinosinusitis With Nasal Polyps

Yoon YH, Yeon SH, Choi MR, Jang YS, Kim JA, Oh HW, Jun X, Park SK, Heo JY, Rha KS, Kim YM

Purpose: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a complex inflammatory disease of the nasal and paranasal sinus mucosa. The disease is associated with mitochondrial dysfunction, structural changes in the...
Changes in Characteristics of Patients with Liver Cirrhosis Visiting a Tertiary Hospital over 15 Years: a Retrospective Multi-Center Study in Korea

Jang WY, Chung WJ, Jang BK, Hwang JS, Lee HJ, Hwang MJ, Kweon YO, Tak WY, Park SY, Lee SH, Lee CH, Kim BS, Kim SH, Suh JI, Park JG

Background: Liver cirrhosis has become a heavy burden not only for patients, but also for our society. However, little is known about the recent changes in clinical outcomes and characteristics...

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