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Surgical strategy for patients with supratentorial spontaneous intracerebral hemorrhage: minimally invasive surgery and conventional surgery

Jang JH, Cho WS, Hong N, Pang CH, Lee SH, Kang HS, Kim JE

Objective: The role of surgery in spontaneous intracerebral hemorrhage (sICH) is still controversial. We aimed to investigate the effectiveness of minimally invasive surgery (MIS) compared to conventional surgery (CS) for...
Blood Transfusion for Elderly Patients with Hip Fracture: a Nationwide Cohort Study

Jang SY, Cha YH, Yoo JI, Oh T, Kim JT, Park CH, Choy WS, Ha YC, Koo KH

Background: This nationwide study aimed to investigate the blood transfusion status of elderly hip fracture patients and to examine the effect of packed red blood cell transfusion on all-cause mortality. Methods:...
Discovering hidden information in biosignals from patients using artificial intelligence

Yoon D, Jang JH, Choi BJ, Kim TY, Han CH

Biosignals such as electrocardiogram or photoplethysmogram are widely used for determining and monitoring the medical condition of patients. It was recently discovered that more information could be gathered from biosignals...
Changes in Characteristics of Patients with Liver Cirrhosis Visiting a Tertiary Hospital over 15 Years: a Retrospective Multi-Center Study in Korea

Jang WY, Chung WJ, Jang BK, Hwang JS, Lee HJ, Hwang MJ, Kweon YO, Tak WY, Park SY, Lee SH, Lee CH, Kim BS, Kim SH, Suh JI, Park JG

Background: Liver cirrhosis has become a heavy burden not only for patients, but also for our society. However, little is known about the recent changes in clinical outcomes and characteristics...
Exome Chip Analysis of 14,026 Koreans Reveals Known and Newly Discovered Genetic Loci Associated with Type 2 Diabetes Mellitus

Cho SB, Jang JH, Chung MG, Kim SC

Background: Most loci associated with type 2 diabetes mellitus (T2DM) discovered to date are within noncoding regions of unknown functional significance. By contrast, exonic regions have advantages for biological interpretation. Methods:...
Consensus statement on coronary intervention during the coronavirus disease 19 pandemic: from the Korean Society of Interventional Cardiology

Lee KY, Lee BK, Kim WJ, Kang SH, Park TK, Kim SY, Suh JW, Yoon CH, Yang DH, Ryu SK, Kim SH, Lee SY, Chae IH, The Korean Society of Interventional Cardiology COVID-19 Task Force Team

Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by the novel virus severe acute respiratory syndrome coronavirus 2. The first case developed in December, 2019 in Wuhan, China;...
Effectiveness of nivolumab versus regorafenib in hepatocellular carcinoma patients who failed sorafenib treatment

Lee CH, Lee YB, Kim MA, Jang H, Oh H, Kim SW, Cho EJ, Lee KH, Lee JH, Yu SJ, Yoon JH, Kim TY, Kim YJ

Background/Aims: Several treatment options are currently available for patients with hepatocellular carcinoma (HCC) failing previous sorafenib treatment. We aimed to compare the effectiveness of regorafenib and nivolumab in these patients. Methods:...
The effect of susceptibility variants, identified in never-smoking female lung cancer cases, on male smokers

Yoo SS, Kang HG, Choi JE, Hong MJ, Do SK, Lee JH, Lee WK, Lee SY, Lee J, Cha SI, Kim CH, Lee EB, Park JY

Background/Aims: Genome wide and candidate gene association studies have identified polymorphisms associated with the risk of lung cancer in never-smokers. This study was conducted to evaluate the association between 11...
Current Long-Term Pharmacotherapies for the Management of Obesity

Kim BY, Kang SM, Kang JH, Kim KK, Kim B, Kim SJ, Kim YH, Kim JH, Kim JH, Nam GE, Park JY, Son JW, Shin HJ, Oh TJ, Lee H, Jeon EJ, Chung S, Hong YH, Kim CH, Committee of Clinical Practice Guidelines, Korean Society for the Study of Obesity (KSSO)

Obesity is a serious and growing worldwide health challenge associated with type 2 diabetes mellitus, cardiovascular disease, osteoarthritis, some cancers, sleep apnea, asthma, and nonalcoholic fatty liver. The Korean Society...
Evaluating Postoperative Muscle Strength Using Surface Electromyography in Hip Fracture Patient

Yoo JI, Byun H, Kim HS, Jang YJ, Lee CH

Background: To compare the muscle strength of patients with a hip fracture according to the presence of sarcopenia after surgery and the correlation of measured values between a Biodex and...
Effects of probiotics or broccoli supplementation on Helicobacter pylori eradication with standard clarithromycin-based triple therapy

Chang YW, Park YM, Oh CH, Oh SJ, Cho JH, Kim JW, Jang JY

Background/Aims: The eradication failure rate of standard triple therapy (proton pump inhibitor, clarithromycin, and amoxicillin) for Helicobacter pylori infection has increased owing to antibiotic resistance in Korea. We assessed whether...
Surgical Outcomes of Type A Aortic Dissection at a Small- Volume Medical Center: Analysis according to the Extent of Surgery

Lee CH, Cho JW, Jang JS, Yoon TH

Background: Despite progress in treatment, Stanford type A aortic dissection is still a life-threatening disease. In this study, we analyzed surgical outcomes in patients with Stanford type A aortic dissection...
Nutrikinetic study of fermented soybean paste (Cheonggukjang) isoflavones according to the Sasang typology

Kim MJ, Lee DH, Ahn J, Jang YJ, Ha TY, Do E, Jung CH

BACKGROUND/OBJECTIVES: In Oriental medicine, certain foods may be beneficial or detrimental based on an individual's constitution; however, the scientific basis for this theory is insufficient. The purpose of this study...
The effects of three novel probiotics isolated from the Korean fermented food Kimchi on the stress-induced defecation of rats

Kim MJ, Min YW, Lee C, Jang YS, Kim CH, Chang DK

Purpose: The interest in novel probiotics that improve symptoms of irritable bowel syndrome (IBS) has been growing trend. This study aims to investigate the probiotic effect of three kinds of...
Effects of Novel Probiotics in a Murine Model of Irritable Bowel Syndrome

Chung HG, Min YW, Lee C, Hong SN, Won JY, Jang JA, Kim CH, Chang DK

BACKGROUND/AIMS: Dysbiosis is an important factor in the pathogenesis of irritable bowel syndrome (IBS). Several studies have reported promising results using probiotics for the treatment of IBS. This study evaluated...
Role of Efflux Pump Gene adeIJK to Multidrug Resistance in Acinetobacter baumannii Clinical Isolates

Choi JA, Kim CM, Jang SJ, Cho SS, Jang CH, Ko YJ, Kang SH, Park G

BACKGROUND: The emergence of multidrug-resistant Acinetobacter baumannii as a nosocomial pathogen is one of the major public health problems. The aim of this study was to evaluate the role of...
Determining the Most Appropriate Assistive Walking Device Using the Inertial Measurement Unit-Based Gait Analysis System in Disabled Patients

Lee J, Bae CH, Jang A, Yang S, Bae H

Objective To evaluate the gait pattern of patients with gait disturbances without consideration of defilades due to assistive devices. This study focuses on gait analysis using the inertial measurement unit...
Effect of Operator Volume on In-Hospital Outcomes Following Primary Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction: Based on the 2014 Cohort of Korean Percutaneous Coronary Intervention (K-PCI) Registry

Lee JH, Eom SY, Kim U, Lee CH, Son JW, Jeon DW, Bae JH, Oh SK, Cha KS, Suh Y, Koh YY, Yang TH, Shim DK, Bae JW, Park JS

BACKGROUND AND OBJECTIVES: The relationship between operator volume and outcomes of percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI) has not been fully investigated. We aimed to...
The Effect of Prenatal Cadmium Exposure on Attention-deficit/Hyperactivity Disorder in 6-Year-old Children in Korea

Kim W, Jang Y, Lim YH, Kim BN, Shin CH, Lee YA, Kim JI, Hong YC

Objectives: Prenatal cadmium (Cd) exposure may be associated with attention-deficit/hyperactivity disorder (ADHD) in children. Therefore, the objective of this study was to examine the relationship between Cd exposure during gestation...
Effect of Pneumonia on All-cause Mortality after Elderly Hip Fracture: a Korean Nationwide Cohort Study

Jang SY, Cha Y, Yoo JI, Yu YT, Kim JT, Park CH, Choy W

BACKGROUND: The purposes of this study were 1) to investigate the incidence of pneumonia during hospitalization in elderly hip fracture patients, 2) to evaluate the effect of pneumonia on 30...

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