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Clinical Implication of Concordant or Discordant Genomic Profiling between Primary and Matched Metastatic Tissues in Patients with Colorectal Cancer

Choi JY, Choi S, Lee M, Park YS, Sung JS, Chang WJ, Kim JW, Choi YJ, Kim J, Kim DS, Lee SH, Seok J, Park KH, Kim SH, Kim YH

  • Cancer Res Treat.
  • 2020 Jul;52(3):764-778.
  • doi: 10.4143/crt.2020.044
Purpose The purpose of this study was to identify the concordant or discordant genomic profiling between primary and matched metastatic tumors in patients with colorectal cancer (CRC) and to explore the...
Effects of Early Phosphorus Intake on Respiratory Distress in Extremely Low-Birth-Weight Infants

Bae HJ, Yoon HW, Kim MJ, Jung AH, Jung SH, Hahn HJ, Jo YH, Cho YS, Kim EK, Shin SH, Song IG, Shin SH

  • Neonatal Med.
  • 2019 Aug;26(3):155-161.
  • doi: 10.5385/nm.2019.26.3.155
PURPOSE: This study was aimed to investigate the effect of early phosphorus intake on respiratory distress in extremely low-birth-weight infants (ELBWIs) with a high incidence of hypophosphatemia. METHODS: We performed a...
Clinical Analysis of External Auditory Canal Osteoma

Kim YS, Kang MH, Choi YS, Shin SO, Jung HJ

  • Korean J Otorhinolaryngol-Head Neck Surg.
  • 2019 Jun;62(6):332-335.
  • doi: 10.3342/kjorl-hns.2018.00780
BACKGROUND AND OBJECTIVES: External auditory canal osteoma is an uncommon benign lesion and represents as unilateral solitary pedunculated mass. The aim of this study is to evaluate the clinical symptoms...
Heat shock protein 70 increases cell proliferation, neuroblast differentiation, and the phosphorylation of CREB in the hippocampus

Kwon HJ, Kim W, Jung HY, Kang MS, Kim JW, Hahn KR, Yoo DY, Yoon YS, Hwang IK, Kim DW

  • Lab Anim Res.
  • 2019 Dec;35(4):154-164.
  • doi: 10.1186/s42826-019-0020-2
In the present study, we investigated the effects of heat shock protein 70 (HSP70) on novel object recognition, cell proliferation, and neuroblast differentiation in the hippocampus. To facilitate penetration into...
Bacopa monnieri extract improves novel object recognition, cell proliferation, neuroblast differentiation, brain-derived neurotrophic factor, and phosphorylation of cAMP response element-binding protein in the dentate gyrus

Kwon HJ, Jung HY, Hahn KR, Kim W, Kim JW, Yoo DY, Yoon YS, Hwang IK, Kim DW

  • Lab Anim Res.
  • 2018 Dec;34(4):239-247.
  • doi: 10.5625/lar.2018.34.4.239
Bacopa monnieri is a medicinal plant with a long history of use in Ayurveda, especially in the treatment of poor memory and cognitive deficits. In the present study, we hypothesized...
Changes of myelin basic protein in the hippocampus of an animal model of type 2 diabetes

Nam SM, Kwon HJ, Kim W, Kim JW, Hahn KR, Jung HY, Kim DW, Yoo DY, Seong JK, Hwang IK, Yoon YS

  • Lab Anim Res.
  • 2018 Dec;34(4):176-184.
  • doi: 10.5625/lar.2018.34.4.176
In this study, we observed chronological changes in the immunoreactivity and expression level of myelin basic protein (MBP), one of the most abundant proteins in the central nervous system, in...
The Difference of Body Mass Index According to Smart Phone Proficiency in Koreans over the Age of 60

Kim JS, Kim JW, Hahn S, Kim YS

  • Korean J Sports Med.
  • 2018 Dec;36(4):189-196.
  • doi: 10.5763/kjsm.2018.36.4.189
PURPOSE: The purpose of this study was to compare the difference of body mass index (BMI) to smart phone proficiency in men and women over the age of 60. METHODS: Patients...
Reduction of Isolated Zygomatic Arch Fractures with Gillies Approach

Shin DK, Kim YS, Shim WS, Jung HJ

  • Korean J Otorhinolaryngol-Head Neck Surg.
  • 2018 Nov;61(11):588-592.
  • doi: 10.3342/kjorl-hns.2017.01109
BACKGROUND AND OBJECTIVES: The incidence of facial bone fracture is increasing. The zygomatic bone, due to its anatomical prominence, is the second most common site of all facial bone fractures....
Enthesitis-related Arthritis

Hahn YS

  • J Rheum Dis.
  • 2018 Oct;25(4):221-230.
  • doi: 10.4078/jrd.2018.25.4.221
Enthesitis-related arthritis (ERA) is a disease predominantly affecting the joints and entheses of the lower extremities and has the potential to eventually affect the sacroiliac joints and spine evolving to...
Accuracy of maximal expiratory flow-volume curve curvilinearity and fractional exhaled nitric oxide for detection of children with atopic asthma

Park SH, Im MJ, Eom SY, Hahn YS

  • Korean J Pediatr.
  • 2017 Sep;60(9):290-295.
  • doi: 10.3345/kjp.2017.60.9.290
PURPOSE: Airway pathology in children with atopic asthma can be reflected by the concave shape of the maximal expiratory flow-volume (MEFV) curve and high fractional exhaled nitric oxide (FeNO) values....
Immunohistochemical localization of glucose transporter 1 and 3 in the scrotal and abdominal testes of a dog

Hahn KR, Jung HY, Yoo DY, Kim JW, Kim YH, Jo YK, Kim GA, Chung JY, Choi JH, Hwang IK, Jang G, Yoon YS

  • Lab Anim Res.
  • 2017 Jun;33(2):114-118.
  • doi: 10.5625/lar.2017.33.2.114
Glucose is essential for testicular function; the uptake of carbohydrate-derived glucose by cells is mediated by glucose transporters (GLUTs). In the present study, we investigated the activity of GLUT1 and...
Congenital Cholesteatoma: Analysis of Risk Factors for the Postoperative Recurrence

Oh YS, Kim JM, Jung HJ, Shin SO, Choi YS

  • Korean J Otorhinolaryngol-Head Neck Surg.
  • 2017 Nov;60(11):554-558.
  • doi: 10.3342/kjorl-hns.2017.00346
BACKGROUND AND OBJECTIVES: The incidence of recurrence after surgery of congenital cholesteatoma is increasing due to the widespread use of otoendoscopy as well as an increased awareness of these lesions...
Establishment of hydrochloric acid/lipopolysaccharide-induced pelvic inflammatory disease model

Oh Y, Lee J, Kim HC, Hahn TW, Yoon BI, Han JH, Kwon YS, Park JJ, Koo DB, Rhee KJ, Jung BD

  • J Vet Sci.
  • 2016 Sep;17(3):413-419.
  • doi: 10.4142/jvs.2016.17.3.413
Pelvic inflammatory disease (PID), which is one of the most problematic complications experienced by women with sexually transmitted diseases, frequently causes secondary infections after reproductive abnormalities in veterinary animals. Although...
Beta Blockers or Calcium Channel Blockers as Primary Antianginal Drug after Percutaneous Coronary Intervention: Prescription Pattern and its association with Clinical Outcome

Noh SY, Jo YH, Cho YS, Hahn HJ, Lee HY, Lee JY

  • Korean J Clin Pharm.
  • 2016 Sep;26(3):213-219.
  • doi: 10.0000/kjcp.2016.26.3.213
OBJECTIVE: Although guideline recommends beta blockers (BBs) as first line antianginal agent and calcium channel blockers (CCBs) as alternatives after percutaneous coronary intervention (PCI), the prescription patterns in real practice...
Subclinical Hypothyroidism in Childhood Cancer Survivors

Lee HJ, Hahn SM, Jin SL, Shin YJ, Kim SH, Lee YS, Kim HS, Lyu CJ, Han JW

  • Yonsei Med J.
  • 2016 Jul;57(4):915-922.
  • doi: 10.3349/ymj.2016.57.4.915
PURPOSE: In childhood cancer survivors, the most common late effect is thyroid dysfunction, most notably subclinical hypothyroidism (SCH). Our study evaluated the risk factors for persistent SCH in survivors. MATERIALS AND...
The Immune Landscape in Nonalcoholic Steatohepatitis

Narayanan , Surette FA, Hahn YS

  • Immune Netw.
  • 2016 Jun;16(3):147-158.
  • doi: 10.4110/in.2016.16.3.147
The liver lies at the intersection of multiple metabolic pathways and consequently plays a central role in lipid metabolism. Pathological disturbances in hepatic lipid metabolism are characteristic of chronic metabolic...
Symptom Interval and Patient Delay Affect Survival Outcomes in Adolescent Cancer Patients

Jin SL, Hahn SM, Kim HS, Shin YJ, Kim SH, Lee YS, Lyu CJ, Han JW

  • Yonsei Med J.
  • 2016 May;57(3):572-579.
  • doi: 10.3349/ymj.2016.57.3.572
PURPOSE: Unique features of adolescent cancer patients include cancer types, developmental stages, and psychosocial issues. In this study, we evaluated the relationship between diagnostic delay and survival to improve adolescent...
House dust mite-specific immunoglobulin E and longitudinal exhaled nitric oxide measurements in children with atopic asthma

Lee YK, Yang S, Park J, Kim H, Hahn YS

  • Korean J Pediatr.
  • 2015 Mar;58(3):89-95.
  • doi: 10.3345/kjp.2015.58.3.89
PURPOSE: House dust mite (HDM) has been suggested to be the most important aeroallergen responsible for atopic asthma in Korea. We aimed to investigate that specific IgE antibodies to HDM...
Effects of Total Thyroidectomy and Radioactive Iodine Therapy for Thyroid Cancer Patients on Sleep Apnea and Snoring

Oh SH, Kim CS, Choi MR, Choi EH, Kim HW, Hahn JH, Kim TH, Kim BJ, Park YS, Eun HJ

  • J Korean Neuropsychiatr Assoc.
  • 2015 Nov;54(4):495-505.
  • doi: 10.4306/jknpa.2015.54.4.495
OBJECTIVES: Some paper claim thyroidectomy decreases snoring and sleep apnea symptoms and the opposite. The aim of this study is to evaluate and compare the effects of sleep apnea and...
Relationships of bronchodilator response with asthma control and fractional exhaled nitric oxide in children with atopic asthma

Park J, Lee YK, Kim H, Hahn YS

  • Allergy Asthma Respir Dis.
  • 2015 Jan;3(1):40-46.
  • doi: 10.4168/aard.2015.3.1.40
PURPOSE: Because bronchodilator response (BDR) is variable among asthmatic patients, there are practical limitations in using BDR to assess asthma control. We investigated the relationships of BDR with asthma control...

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