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Serum Testosterone Level Can Be Predictive Factor for Upstaging in Clinically Localized Prostate Cancer

Kwon SO, Byeon KH, Chung JW, Ha YS, Choi SH, Kim BS, Kim HT, Kim TH, Yoo ES, Yoon GS, Lee JN, Kwon TG

Purpose: To determine an appropriate surgical technique, it is important to predict pathological results for patientswith clinically localized prostate cancer (PCa) eligible for nerve-sparing radical prostatectomy (NSRP). Severalstudies have highlighted...
Impact of Multiple Prostate Biopsies: Risk of Perioperative Complications and Biochemical Recurrence After Radical Prostatectomy

Park KM, Chung JW, Kang JK, Shin TJ, Kwon SY, Jang HC, Ha YS, Choi SH, Jung W, Lee JN, Kim BH, Kim BS, Kim HT, Kim JS, Kim TH, Yoo ES, Lee KS, Kim CI, Chung SK, Kwon TG

Purpose: The aim of this study was to analyze the perioperative complications and oncological outcomes of radical prostatectomy (RP) in patients who underwent multiple prostate biopsies. Materials and Methods: A total...
Efficacy of Androgen Deprivation Therapy in Patients with Metastatic Castration-Resistant Prostate Cancer Receiving Docetaxel-Based Chemotherapy

Min K, Chung JW, Ha YS, Lee JN, Kim BS, Kim HT, Kim TH, Yoo ES, Kwon TG, Chung SK, Tanaka M, Egawa S, Kimura T, Choi SH

PURPOSE: The purpose of this study was to determine the comparative effectiveness of androgen deprivation therapy (ADT) combined with docetaxel (DTX)-based chemotherapy in Korean and Japanese castration-resistant prostate cancer (CRPC)...
Big Data Statistical Analysis of Facial Fractures in Korea

Park CH, Chung KJ, Kim TG, Lee JH, Kim IK, Kim YH

BACKGROUND: The big data provided by Health Insurance Review and Assessment (HIRA) contains data from nearly all Korean populations enrolled in the National Health Insurance Service. We aimed to identify...
Preparation and Characterization of Human Adipose Tissue-Derived Extracellular Matrix, Growth Factors, and Stem Cells: A Concise Review

Chun SY, Lim JO, Lee EH, Han MH, Ha YS, Lee JN, Kim BS, Park MJ, Yeo M, Jung B, Kwon TG

BACKGROUND: Human adipose tissue is routinely discarded as medical waste. However, this tissue may have valuable clinical applications since methods have been devised to effectively isolate adipose-derived extracellular matrix (ECM),...
Susceptibility of the Index Urinary Tract Infection to Prophylactic Antibiotics Is a Predictive Factor of Breakthrough Urinary Tract Infection in Children with Primary Vesicoureteral Reflux Receiving Continuous Antibiotic Prophylaxis

Lee JN, Byeon KH, Woo MJ, Baek HS, Cho MH, Jeong SY, Lee SM, Ham JY, Ha YS, Kim HT, Yoo ES, Kwon TG, Chung SK

BACKGROUND: Few studies have reported on breakthrough urinary tract infection (UTI) associated with the susceptibility of index UTI to prophylactic antibiotics in children with primary vesicoureteral reflux (VUR) receiving continuous...
In Vivo Safety and Regeneration of Long-Term Transported Amniotic Fluid Stem Cells for Renal Regeneration

Yu NH, Chun SY, Ha YS, Kim HT, Lih E, Kim DH, Kim J, Chung JW, Song PH, Yoo ES, Chung SK, Han DK, Kim BS, Kwon TG

BACKGROUND: Despite major progress in stem cell therapy, our knowledge of the characteristics and tissue regeneration potency of long-term transported cells is insufficient. In a previous in vitro study, we...
Clinical significance of the De Ritis ratio for detecting prostate cancer in a repeat prostate biopsy

Ha H, Chung JW, Ha YS, Choi SH, Lee JN, Kim BS, Kim HT, Kim TH, Yoon GS, Kwon TG, Chung SK, Yoo ES

PURPOSE: We evaluated factors predicting a positive repeat biopsy result in patients with an initial negative prostate biopsy result. MATERIALS AND METHODS: This study included 124 patients in whom prostate cancer...
Clinical and Radiographic Characteristics of Neuro-Behçet's Disease in South Korea

Kim SW, Kim TG, Oh J, Kim DY, Choi YC, Kim SM, Shin HY, Bang D

BACKGROUND AND PURPOSE: Neurological involvement in Behçet's disease [neuro-Behçet's disease (NBD)] is uncommon, but it is worth investigating since it can cause substantial disability. However, difficulties exist in understanding the...
Breast reconstruction statistics in Korea from the Big Data Hub of the Health Insurance Review and Assessment Service

Kim JW, Lee JH, Kim TG, Kim YH, Chung KJ

BACKGROUND: Previously, surveys have been used to investigate breast reconstruction statistics. Since 2015, breast reconstruction surgery after mastectomy has been covered by the National Health Insurance Service in Korea, and...
Clinical characteristics of postoperative febrile urinary tract infections after ureteroscopic lithotripsy

Kim JW, Lee YJ, Chung JW, Ha YS, Lee JN, Yoo ES, Kwon TG, Kim BS

PURPOSE: Ureteroscopic lithotripsy (URS) is gaining popularity for the management of ureteral stones and even renal stones, with high efficacy and minimal invasiveness. Although this procedure is known to be...
A Novel Dorsal Slit Approached Non-Ischemic Partial Nephrectomy Method for a Renal Tissue Regeneration in a Mouse Model

Chun SY, Kim DH, Kim JS, Kim HT, Yoo ES, Chung JW, Ha YS, Song PH, Joung YK, Han DK, Chung SK, Kim BS, Kwon TG

BACKGROUND: Kidney ischemia-reperfusion (IR) via laparotomy is a conventional method for kidney surgery in a mouse model. However, IR, an invasive procedure, can cause serious acute and chronic complications through...
In Vivo Validation Model of a Novel Anti-Inflammatory Scaffold in Interleukin-10 Knockout Mouse

Kim JY, Chun SY, Lee SH, Lih E, Kim J, Kim DH, Ha YS, Chung JW, Lee JN, Kim BS, Kim HT, Yoo ES, Han DK, Kwon TG, Jang BI

BACKGROUND: We fabricated anti-inflammatory scaffold using Mg(OH)2-incorporated polylactic acid-polyglycolic acid copolymer (MH-PLGA). To demonstrate the anti-inflammatory effects of the MH-PLGA scaffold, an animal model should be sensitive to inflammatory responses....
Down-regulation of transient receptor potential melastatin member 7 prevents migration and invasion of renal cell carcinoma cells via inactivation of the Src and Akt pathway

Ha YS, Kim YY, Yu NH, Chun SY, Choi SH, Lee JN, Kim BS, Yoo ES, Kwon TG

PURPOSE: Transient receptor potential melastatin member 7 (TRPM7), an ion channel and serine/threonine protein kinase, has been linked with distinct human malignancies. However, the role of TRPM7 in renal cell...
The relationship between low survival and acute increase of tumor necrosis factor α expression in the lung in a rat model of asphyxial cardiac arrest

Park Y, Tae HJ, Cho JH, Kim IS, Ohk TG, Park CW, Moon JB, Shin MC, Lee TK, Lee JC, Park JH, Ahn JH, Kang SH, Won MH, Cho JH

Cardiac arrest (CA) is sudden loss of heart function and abrupt stop in effective blood flow to the body. The patients who initially achieve return of spontaneous circulation (RoSC) after...
Erectile Function and Long-term Oncologic Outcomes of Nerve-Sparing Robot-Assisted Radical Cystectomy: Comparison With Open Radical Cystectomy

Kwon SY, Ha YS, Kim TH, Kwon TG

PURPOSE: We performed nerve-sparing robot-assisted radical cystectomy (nsRARC) and compared the operative outcomes of nsRARC and open radical cystectomy (ORC). MATERIALS AND METHODS: The data of 38 patients that underwent ORC...
A Higher Ratio of Serum Calcium to Magnesium Is Associated With Aggressive Clinicopathological Characteristics in the Patients Who Underwent Radical Prostatectomy

Kim SW, Lee YJ, Chung JW, Ha YS, Choi SH, Lee JN, Kim BS, Kim HT, Kim TH, Yoo ES, Kwon TG

PURPOSE: Changes in magnesium (Mg) concentration and calcium-to-magnesium ratio (Ca/Mg) play a critical role in cancer cell proliferation. In this study, we evaluated the association between preoperative Ca/Mg ratio and...
Laminin and Platelet-Derived Growth Factor-BB Promote Neuronal Differentiation of Human Urine-Derived Stem Cells

Kim JY, Chun SY, Park JS, Chung JW, Ha YS, Lee JN, Kwon TG

Urine-derived stem cells (USCs) are considered as a promising cell source capable of neuronal differentiation. In addition, specific growth factors and extracellular matrix are essential for enhancing their neuronal differentiation...
Oncological and functional outcomes following robot-assisted laparoscopic radical prostatectomy at a single institution: a minimum 5-year follow-up

Kang JK, Chung JW, Chun SY, Ha YS, Choi SH, Lee JN, Kim BS, Yoon GS, Kim HT, Kim TH, Kwon TG

BACKGROUND: To evaluate mid-term oncological and functional outcomes in patients with prostate cancer treated by robot-assisted laparoscopic radical prostatectomy (RALP) at our institution. METHODS: We retrospectively reviewed the medical records of...
Wound healing effects of paste type acellular dermal matrix subcutaneous injection

Lee JH, Kim JW, Lee JH, Chung KJ, Kim TG, Kim YH, Kim KJ

BACKGROUND: Acellular dermal matrix (ADM) helps wound healing by stimulating angiogenesis, acting as a chemoattractant for endothelial cells, providing growth factors, and permitting a substrate for fibroblasts to attach. The...

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