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Effects of Diabetes Mellitus on the Disposition of Tofacitinib, a Janus Kinase Inhibitor, in Rats

Gwak EH, Yoo HY, Kim SH

  • Biomol Ther.
  • 2020 Jul;28(4):361-369.
  • doi: 10.4062/biomolther.2020.006
Tofacitinib, a Janus kinase inhibitor, was developed for the treatment of rheumatoid arthritis. Recently, it has been associated with an increased change in arthritis development in patients with diabetes. Herein,...
Concurrent Chemoradiotherapy with Temozolomide Followed by Adjuvant Temozolomide for Newly Diagnosed Glioblastoma Patients: A Retrospective Multicenter Observation Study in Korea

Kim BS, Seol HJ, Nam DH, Park CK, Kim IH, Kim TM, Kim JH, Cho YH, Yoon SM, Chang JH, Kang SG, Kim EH, Suh CO, Jung TY, Lee KH, Kim CY, Kim IA, Hong CK, Yoo H, Kim JH, Kang SH, Kang MK, Kim EY, Kim SH, Chung DS, Hwang SC, Song JH, Cho SJ, Lee SI, Lee YS, Ahn KJ, Kim SH, Lim DH, Gwak HS, Lee SH, Hong YK

  • Cancer Res Treat.
  • 2017 Jan;49(1):193-203.
  • doi: 10.4143/crt.2015.473
PURPOSE: The purpose of this study was to investigate the feasibility and survival benefits of combined treatment with radiotherapy and adjuvant temozolomide (TMZ) in a Korean sample. MATERIALS AND METHODS: A...
Ultrasound-guided evaluation of the bifurcation of the femoral artery and vein in pediatric patients

Song JG, Lee YK, Lee JD, Lee EH, Park JH, Gwak M, Noh GJ

  • Korean J Anesthesiol.
  • 2009 Mar;56(3):290-294.
  • doi: 10.4097/kjae.2009.56.3.290
BACKGROUND: The femoral arteries (FA) and femoral veins (FV) are useful access sites for diagnostic and interventional procedures. In adults, the usual puncture sites are 1-3 cm distal from the...
Airway Partial Obstruction by Internal Hermiation of Armored Endotracheal Tube: A case report

Gwak M, Hwang HS, Suk EH, Park PH

  • Korean J Crit Care Med.
  • 2002 Jun;17(1):29-33.
During general anesthesia, intubation with kink-resistant armored tubes permit the anesthesiologist to work some distance from the surgical field during operation on the head and neck or with patients whose...
Effects of Poly (ADP-ribose) Polymerase Inhibitor on Hypoxic-ischemic Injury in the Neonatal Rat Brain: 1H Magnetic Resonance Spectroscopic Study

Suk EH, Hwang HS, Lim KH, Lee JH, Gwak MJ, Park PH

  • Korean J Anesthesiol.
  • 2002 Feb;42(2):228-240.
  • doi: 10.4097/kjae.2002.42.2.228
BACKGROUND: Poly (ADP-ribose) polymerase (PARP) has been described as an important candidate for mediation of neurotoxicity after brain ischemia. This study was purposed to evaluate the effects of...
Effects of iontophoretically applied substance P, calcitonin gene-related peptide on excitability of dorsal horn neurones in rats

Leem JW, Gwak YS, Lee EH, Chung SS, Kim YS, Nam TS

  • Yonsei Med J.
  • 2001 Feb;42(1):74-83.
  • doi: 10.3349/ymj.2001.42.1.74
Spontaneous pain, allodynia and hyperalgesia are well known phenomena following peripheral nerve or tissue injury, and it is speculated that secondary hyperalgesia and allodynia, are generally thought...
Effect of a Meal on Cardiac Performance in Patients with Coronary Artcry Disease

Park HS, Lee BR, Jung ER, Gwak DH, Yang DH, Shin SC, Hwang JH, Jo YG, Chae SC, Jeon JE, Park EH

  • J Korean Soc Echocardiogr.
  • 2000 Jun;8(1):54-58.
BACKGROUND: It has been well recognized that exercise tolerance and angina threshold in patients with coronary artery disease (CAD) are reduced after a meal. But precise mechanism leading to the...

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