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Updates on ankylosing spondylitis: pathogenesis and therapeutic agents

Kim SH, Lee SH

Ankylosing spondylitis (AS) is an autoinflammatory disease that manifests with the unique feature of enthesitis. Gut microbiota, HLA-B*27, and biomechanical stress mutually influence and interact resulting in setting off a...
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Corrigendum: Korean treatment recommendations for patients with axial spondyloarthritis

Seo MR, Yeo J, Park JW, Lee YA, Lee JH, Kang EH, Ji SM, Kwon SR, Kim SK, Kim TJ, Kim TH, Kim HW, Park MC, Shin K, Lee SH, Lee EY, Cha HS, Shim SC, Yoon Y, Lee SH, Lim JH, Baek HJ, on behalf of the Korean Society of Spondyloarthritis Research

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A Case of Recurrent Pneumonia with a Calcific Density

Recurrent Pneumonia is sometimes associated with bronchial abnormalities. Recently, we experienced a case of rare bronchial foreign body (tooth) in the patient who had a history of being intubated 3...
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Application of Cartilage Extracellular Matrix to Enhance Therapeutic Efficacy of Methotrexate

Seo JW, Jo SH, Kim SH, Choi BH, Cho H, Yoo JJ, Park SH

BACKGROUND: Rheumatoid arthritis (RA) is characterized by chronic inflammation and joint damage. Methotrexate (MTX), a commonly used disease-modifying anti-rheumatic drug (DMARD) used in RA treatment. However, the continued use of...
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A Study on the Status and Genetic Characteristics of Carbapenem Resistance of Clinical-derived Bacteria in Northern Gyeonggi Province

Lee Cm, Kim KA, Oh SH, Jang MJ, You SH, Park HB, Ko DJ

Background: Carbapenem-resistant Enterobacterales (CRE) is an infectious disease caused by an Enterobacteriaceae species resistant to one or more of the carbapenem antibiotics. Methods: Strains collected in clinical trials from 2018 to...
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Chronic Obstructive Pneumonitis

Foreign body aspiration in adult commonly result in proximal airway obstruction and acute life threating asphyxia. Often asymptomatic initially and result in respiratory symptoms for weeks to years before diagnosis....
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Etiology and Clinical Characteristics of Community-Acquired Pneumonia in Korean Children During the PreCOVID-19 Period, 2015-2020

Suh JH, Ahn B, Song SH, Choi S, Choi SH, Lee H, Han MS, Park JY, Choi EH, Yun KW

Background: There have been many epidemiologic studies on community-acquired pneumonia (CAP) among children, most of which had substantial limitations. This study investigated the etiologic distribution and clinical characteristics of CAP...
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A Clinical Investigation of Spontaneous Pneumothorax

The authors reviewed 124 patients of spontaneous pneumothorax who were treated in Jeonju Presbyterian Medical Center from 1970 to 1981. The following results were obtained: 1) Male was more frequently affected than...
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Tracheal Stenosis Following Assisted Ventilation

Tracheal stenosis in patients who have been treated for respiratory failure by assisted ventilation withcuffed tracheostomy tube have been increasingly recognized since late 1960s. Assisted ventilation with endotracheal intubation or tracheostomy...
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Fiberoptic Bronchoscopy in the Diagnosis of Pulmonary and Endobronchial Tuberculosis

The bronchofiberscopy has been popular in diagnosing pulmonary disease since 1968. Recently there are some reports that fiberoptic bronchoscopy is a useful procedure for evaluating suspected cases of tuberculosis. In Our country...
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Hypersenstivity Pheumonitis

Hypersensitivity pneumonitis has many clinical, roentgenographic and pathophysiologic features that may be indistinguishable from idiopathic pulmonary fibrosis. But, there are characteristics of hypersensitivity pneumonitis that may be enable a specific...
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Real-world effectiveness of a single conventional diseasemodifying anti-rheumatic drug (cDMARD) plus an anti-TNF agent versus multiple cDMARDs in rheumatoid arthritis: a prospective observational study

So MW, Kim SH, Kim DW, Sung YK, Choe JY, Lee SI, Hur JW, Lee HS, Lee SH, Kim JR

Objective: The objective of this prospective, observational multicenter study (NCT03264703) was to compare the effectiveness of single conventional disease-modifying anti-rheumatic drug (cDMARD) plus anti-tumor necrosis factor (TNF) therapy versus multiple...
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A Case of Hidden Lung Cancer Presented by Hydropneumothorax

Lung cancer is usually presented with respiratory symptoms such as cough, sputum, dyspnea or chest pain and it is also found incidentally on routine chest X-ray. Rarely lung cancer is...
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Serotype Distribution and Antimicrobial Resistance of Streptococcus pneumoniae Causing Invasive Pneumococcal Disease in Korea Between 2017 and 2019 After Introduction of the 13-Valent Pneumococcal Conjugate Vaccine

Kim GR, Kim EY, Kim SH, Lee HK, Lee J, Shin JH, Kim YR, Song SA, Jeong J, Uh Y, Kim YK, Yong D, Kim HS, Kim S, Kim YA, Shin KS, Jeong SH, Ryoo N, Shin JH

Background: Streptococcus pneumoniae is a serious pathogen causing various infections in humans. We evaluated the serotype distribution and antimicrobial resistance of S. pneumoniae causing invasive pneumococcal disease (IPD) after introduction...
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Combination treatment of a 1,064-nm picosecond domain Nd:YAG laser and a pneumatic needle-less injector for en coup de sabre in Republic of Korea: a case report

Shin SH, Han HS, Choi SY, Yoo KH

En coup de sabre is a form of localized scleroderma involving the frontoparietal scalp and forehead. It often results in cosmetic disfiguring and severe psychological distress. Herein, we report a...
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The Diagnostic Value of Pleural Fluid pH

The pH of pleural fluids were measured in 53 patients with pleural effusion. The results were as follows: 1) Of the 53 effusions, 12 were classified as transudates, of which 5 patients...
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Usefulness of Computed Tomography Guided Percutaneous Fine Needle Aspiration Lung Biopsy

Computed tomography (CT)-guided fine needle aspiration biopsies were done in 62 patients with abnormal mass-like densities on routine chest films. When CT-guided needle aspiration revealed no diagnostic findings in these...
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Microbial Isolates from Central Air-Conditioning Systems in Hospital

In order to elucidate a possible role of the central air-conditioning system in hospital-acquired infections, the dusts and air were sampled from air-conditioning systems in general ward, corridor, medical ICU,...
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Comparison of the characteristics of macrolide-sensitive and macrolide-resistant Mycoplasma pneumoniae pneumonia requiring hospitalization in children

Lee E, Kim SH

Purpose: This study was performed to investigate differences in clinical, laboratory, and radiologic features of clinical course between macrolide-resistant Mycoplasma pneumoniae (MRMP) and macrolide-sensitive Mycoplasma pneumoniae (MSMP) pneumonia in children. Methods:...
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General Anesthesia and Endoscopic Upper Gastrointestinal Tumor Resection

Kim SH

Appropriate sedation and analgesia are crucial for successful endoscopic procedures, patient safety, and satisfaction. Endoscopic resection for upper gastrointestinal tumors requires a deep sedation level because the procedure is lengthy...
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